Effect of tobacco smoking on the epigenetic age of human respiratory organs

An epigenetic biomarker of aging for lifespan and healthspan

(2018) Morgan E. Levine et al.   Aging-US

Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis

(2018) Neeraj Vij et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Global methylation profiles in buccal cells of long-term smokers and moist snuff consumers

(2018) Walter J. Jessen et al.   BIOMARKERS

Dkk3 dependent transcriptional regulation controls age related skeletal muscle atrophy

(2018) Jie Yin et al.   Nature Communications

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD

(2018) Rachel L. Clifford et al.   Clinical Epigenetics

Asbestos-associated genome-wide DNA methylation changes in lung cancer

(2017) Eeva Kettunen et al.   INTERNATIONAL JOURNAL OF CANCER

Analysis of Polymorphisms in 58 Potential Candidate Genes for Association with Human Longevity

(2017) Timothy A Donlon et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway

(2017) Valentina Rapisarda et al.   Cell Reports

DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD

(2017) Isaac K. Sundar et al.   Clinical Epigenetics

Specific premature epigenetic aging of cartilage in osteoarthritis

(2016) Laura Vidal-Bralo et al.   Aging-US

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant

(2016) Nataliya Di Donato et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Carbocysteine counteracts the effects of cigarette smoke on cell growth and on the SIRT1/FoxO3 axis in bronchial epithelial cells

(2016) E. Pace et al.   EXPERIMENTAL GERONTOLOGY

Perioral wrinkles are associated with female gender, aging, and smoking: Development of a gender-specific photonumeric scale

(2016) Anna L. Chien et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study

(2016) Srikant Ambatipudi et al.   Epigenomics

Frequent silencing of the candidate tumor suppressor TRIM58 by promoter methylation in early-stage lung adenocarcinoma

(2016) Koichiro Kajiura et al.   Oncotarget

Tobacco smoking and methylation of genes related to lung cancer development

(2016) Xu Gao et al.   Oncotarget

Global DNA methylation patterns in Barrett’s esophagus, dysplastic Barrett’s, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use

(2016) Andrew M. Kaz et al.   Clinical Epigenetics

Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation

(2016) Robert Philibert et al.   Frontiers in Psychiatry

Accelerated epigenetic aging in Down syndrome

(2015) Steve Horvath et al.   AGING CELL

Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

(2015) Morgan E Levine et al.   Aging-US

Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients

(2015) Steve Horvath et al.   Aging-US

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers

(2015) Ana I. Robles et al.   Journal of Thoracic Oncology

Bovine Brain Region-Specific Stearoyl-CoA Desaturase Expression and Fatty Acid Composition

(2015) A. J. Lengi et al.   LIPIDS

RNA-seq analysis of lung adenocarcinomas reveals different gene expression profiles between smoking and nonsmoking patients

(2015) Yafang Li et al.   TUMOR BIOLOGY

CpG island methylation profile in non-invasive oral rinse samples is predictive of oral and pharyngeal carcinoma

(2015) Scott M. Langevin et al.   Clinical Epigenetics

Smoking duration, respiratory symptoms, and COPD in adults aged ≥45 years with a smoking history

(2015) Yong Liu et al.   International Journal of Chronic Obstructive Pulmonary Disease

Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development

(2014) Rong-Qing Geng et al.   ANIMAL BIOTECHNOLOGY

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

(2014) Loukia G Tsaprouni et al.   Epigenetics

Obesity accelerates epigenetic aging of human liver

(2014) S. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways

(2013) Emily A. Vucic et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Smoking cessation in patients with respiratory disease: existing treatments and future directions

(2013) Nancy A Rigotti   Lancet Respiratory Medicine

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Non Smoking for Successful Aging: Therapeutic Perspectives

(2010) V. Nicita-Mauro et al.   CURRENT PHARMACEUTICAL DESIGN

Smoking, aging and the centenarians

(2007) V. Nicita-Mauro et al.   EXPERIMENTAL GERONTOLOGY