DNA Methylation Is Globally Disrupted and Associated with Expression Changes in Chronic Obstructive Pulmonary Disease Small Airways

A Dynamic Bronchial Airway Gene Expression Signature of Chronic Obstructive Pulmonary Disease and Lung Function Impairment

(2013) Katrina Steiling et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Smoke Extract Impairs Adenosine Wound Healing. Implications of Smoke-Generated Reactive Oxygen Species

(2013) Diane S. Allen-Gipson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

DNA Methylation of Transcriptional Enhancers and Cancer Predisposition

(2013) Dvir Aran et al.   CELL

Bridging epigenomics and complex disease: the basics

(2013) Raffaele Teperino et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Combined Analysis of EPHX1, GSTP1, GSTM1 and GSTT1 Gene Polymorphisms in Relation to Chronic Obstructive Pulmonary Disease Risk and Lung Function Impairment

(2013) Ramzi Lakhdar et al.   DISEASE MARKERS

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

(2013) Lauren J. Buro-Auriemma et al.   HUMAN MOLECULAR GENETICS

Integrative Omics Approach Identifies Interleukin-16 as a Biomarker of Emphysema

(2013) Russell P. Bowler et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

GSTCD and INTS12 Regulation and Expression in the Human Lung

(2013) Ma’en Obeidat et al.   PLoS One

Refining Susceptibility Loci of Chronic Obstructive Pulmonary Disease with Lung eqtls

(2013) Maxime Lamontagne et al.   PLoS One

Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

(2013) Parrisa Solaimani et al.   TOXICOLOGICAL SCIENCES

Altered DNA Methylation Profile in Idiopathic Pulmonary Fibrosis

(2012) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Systemic Steroid Exposure Is Associated with Differential Methylation in Chronic Obstructive Pulmonary Disease

(2012) Emily S. Wan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epithelial Pten Controls Acute Lung Injury and Fibrosis by Regulating Alveolar Epithelial Cell Integrity

(2012) Kahori Miyoshi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetics in asthma and COPD

(2012) Michael Kabesch et al.   BIOCHIMIE

A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform

(2012) Joanna J Zhuang et al.   BMC BIOINFORMATICS

RNA-Seq quantification of the human small airway epithelium transcriptome

(2012) Neil R Hackett et al.   BMC GENOMICS

Molecular Signature of Smoking in Human Lung Tissues

(2012) Y. Bosse et al.   CANCER RESEARCH

Methylated Genes in Sputum Among Older Smokers With Asthma

(2012) Akshay Sood et al.   CHEST

Expression of eotaxins in the material from nasal brushing in asthma, allergic rhinitis and COPD patients

(2012) Magdalena Paplińska et al.   CYTOKINE

g-Protein Coupled Receptor Family C, Group 5, Member A ( gprc5a ) Expression Is Decreased in the Adjacent Field and Normal Bronchial Epithelia of Patients with Chronic Obstructive Pulmonary Disease and Non–Small-Cell Lung Cancer

(2012) Junya Fujimoto et al.   Journal of Thoracic Oncology

Trials with ‘epigenetic’ drugs: An update

(2012) Angela Nebbioso et al.   Molecular Oncology

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

DNA Methylation Profiles of Airway Epithelial Cells and PBMCs from Healthy, Atopic and Asthmatic Children

(2012) Dorota Stefanowicz et al.   PLoS One

Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function

(2011) Weiliang Qiu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Involvement of Creatine Kinase B in Cigarette Smoke–Induced Bronchial Epithelial Cell Senescence

(2011) Hiromichi Hara et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Deadly triplex: Smoke, autophagy and apoptosis

(2011) Stefan W. Ryter et al.   Autophagy

Pharmacological antioxidant strategies as therapeutic interventions for COPD

(2011) Irfan Rahman   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Increased interleukin (IL)-8 and decreased IL-17 production in chronic obstructive pulmonary disease (COPD) provoked by cigarette smoke

(2011) Xiaojun Zhang et al.   CYTOKINE

A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13

(2011) M. H. Cho et al.   HUMAN MOLECULAR GENETICS

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

(2011) María Soler Artigas et al.   NATURE GENETICS

Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections

(2011) Yang Zhang et al.   NATURE MEDICINE

Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

(2011) John E. McDonough et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking

(2011) Ann E. Tilley et al.   PLoS One

Genetics of Sputum Gene Expression in Chronic Obstructive Pulmonary Disease

(2011) Weiliang Qiu et al.   PLoS One

Pathologic Caveolin-1 Regulation of PTEN in Idiopathic Pulmonary Fibrosis

(2010) Hong Xia et al.   AMERICAN JOURNAL OF PATHOLOGY

Wood Smoke Exposure and Gene Promoter Methylation Are Associated with Increased Risk for COPD in Smokers

(2010) Akshay Sood et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genome-wide Association Study IdentifiesBICD1as a Susceptibility Gene for Emphysema

(2010) Xiangyang Kong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo

(2010) Renat Shaykhiev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

(2009) Nancy L. Saccone et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Meta-analyses on Suspected Chronic Obstructive Pulmonary Disease Genes

(2009) Joanna Smolonska et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeting the PI3K signaling pathway in cancer

(2009) Kwok-Kin Wong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gene Regulation of CYP4F11 in Human Keratinocyte HaCaT Cells

(2009) Y. Wang et al.   DRUG METABOLISM AND DISPOSITION

Inactive X chromosome-specific reduction in placental DNA methylation

(2009) Allison M. Cotton et al.   HUMAN MOLECULAR GENETICS

Unknown

(2009) Ralf-Harto Hubner et al.   MOLECULAR MEDICINE

Genome-wide association study identifies five loci associated with lung function

(2009) Emmanouela Repapi et al.   NATURE GENETICS

PTEN identified as important risk factor of chronic obstructive pulmonary disease

(2009) H. Dean Hosgood et al.   RESPIRATORY MEDICINE

Nrf2 protects against airway disorders

(2009) Hye-Youn Cho et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Variability in Small Airway Epithelial Gene Expression Among Normal Smokers

(2008) Zeinab Ammous et al.   CHEST

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH

Dysregulation of elastin expression by fibroblasts in pulmonary emphysema: role of cellular retinoic acid binding protein 2

(2008) L Plantier et al.   THORAX

Gene Expression Profiling in Patients with Chronic Obstructive Pulmonary Disease and Lung Cancer

(2007) I-Ming Wang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE