Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study
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Title
Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study
Authors
Keywords
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Journal
PLOS MEDICINE
Volume 17, Issue 1, Pages e1003012
Publisher
Public Library of Science (PLoS)
Online
2020-01-25
DOI
10.1371/journal.pmed.1003012
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Note: Only part of the references are listed.- Astrocyte Biomarkers in Alzheimer’s Disease
- (2019) Stephen F. Carter et al. TRENDS IN MOLECULAR MEDICINE
- Evidence for brain glucose dysregulation in Alzheimer's disease
- (2018) Yang An et al. Alzheimers & Dementia
- Choline the brain and neurodegeneration insights from epigenetics
- (2018) Rola A Bekdash Frontiers in Bioscience-Landmark
- Altered Expression of Urea Cycle Enzymes in Amyloid-β Protein Precursor Overexpressing PC12 Cells and in Sporadic Alzheimer’s Disease Brain
- (2018) Henryk Jęśko et al. JOURNAL OF ALZHEIMERS DISEASE
- Spermidine in health and disease
- (2018) Frank Madeo et al. SCIENCE
- Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study
- (2018) Vijay R. Varma et al. PLOS MEDICINE
- Metabolomics Platform with Capillary Electrophoresis Coupled with High-Resolution Mass Spectrometry for Plasma Analysis
- (2018) Kazunori Sasaki et al. ANALYTICAL CHEMISTRY
- Unsupervised excitation: GABAergic dysfunctions in Alzheimer’s disease
- (2018) Eleonora Ambrad Giovannetti et al. BRAIN RESEARCH
- Role of glutathione in the regulation of epigenetic mechanisms in disease
- (2017) José Luis García-Giménez et al. FREE RADICAL BIOLOGY AND MEDICINE
- Genome instability in Alzheimer disease
- (2017) Yujun Hou et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Targeting nuclear thymidylate biosynthesis
- (2017) James Chon et al. MOLECULAR ASPECTS OF MEDICINE
- Metabolic profile alterations in the postmortem brains of patients with schizophrenia using capillary electrophoresis-mass spectrometry
- (2017) Takashi Fujii et al. SCHIZOPHRENIA RESEARCH
- Molecular signatures of longevity: Insights from cross-species comparative studies
- (2017) Siming Ma et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with γ-secretase and regulates neuronal amyloid β-peptide levels
- (2017) Sophia Schedin-Weiss et al. Alzheimers Research & Therapy
- Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study
- (2017) Stuart G. Snowden et al. PLOS MEDICINE
- Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden
- (2017) Rachel F. Buckley et al. JAMA Neurology
- Neuropathologic Studies of the Baltimore Longitudinal Study of Aging (BLSA)
- (2017) Richard J. O'Brien et al. JOURNAL OF ALZHEIMERS DISEASE
- Is the Urea Cycle Involved in Alzheimer's Disease?
- (2017) Franck Hansmannel et al. JOURNAL OF ALZHEIMERS DISEASE
- Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID)
- (2016) Atticus H. Hainsworth et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
- (2016) Jingshu Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2016) Anthony E. Pegg JOURNAL OF BIOLOGICAL CHEMISTRY
- Unbiased Metabolomic Investigation of Alzheimer’s Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism
- (2016) Giuseppe Paglia et al. JOURNAL OF PROTEOME RESEARCH
- Alzheimer's disease–like pathology has transient effects on the brain and blood metabolome
- (2016) Xiaobei Pan et al. NEUROBIOLOGY OF AGING
- Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission
- (2016) Agenor Limon et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Methionine restriction and life-span control
- (2015) Byung Cheon Lee et al. Annals of the New York Academy of Sciences
- Brain Glutathione Levels – A Novel Biomarker for Mild Cognitive Impairment and Alzheimer’s Disease
- (2015) Pravat K. Mandal et al. BIOLOGICAL PSYCHIATRY
- Transcriptional regulation of N-acetylaspartate metabolism in the 5xFAD model of Alzheimer's disease: Evidence for neuron–glia communication during energetic crisis
- (2015) Samantha Zaroff et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice
- (2015) Cheril Tapia-Rojas et al. Molecular Neurodegeneration
- Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 ( SAT1 ) gene in major depression and suicide
- (2015) Spiro P. Pantazatos et al. NEUROBIOLOGY OF DISEASE
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease
- (2015) Stewart F. Graham et al. PLoS One
- Efficacy of antibody-based therapies to treat Alzheimer's disease: Just a matter of timing?
- (2014) Jonathan Cedernaes et al. EXPERIMENTAL GERONTOLOGY
- Mild Cognitive Impairment and Asymptomatic Alzheimer Disease Subjects
- (2014) Diego Iacono et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition
- (2014) Bo-Eun Yoon et al. JOURNAL OF PHYSIOLOGY-LONDON
- GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease
- (2014) Seonmi Jo et al. NATURE MEDICINE
- Altered arginine metabolism in Alzheimer's disease brains
- (2014) Ping Liu et al. NEUROBIOLOGY OF AGING
- A snapshot of plasma metabolites in first-episode schizophrenia: a capillary electrophoresis time-of-flight mass spectrometry study
- (2014) S Koike et al. Translational Psychiatry
- Glutathione relates to neuropsychological functioning in mild cognitive impairment
- (2013) Shantel L. Duffy et al. Alzheimers & Dementia
- Impaired Glutathione Synthesis in Neurodegeneration
- (2013) Koji Aoyama et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Power failure: why small sample size undermines the reliability of neuroscience
- (2013) Katherine S. Button et al. NATURE REVIEWS NEUROSCIENCE
- Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease
- (2013) Luke Whiley et al. NEUROBIOLOGY OF AGING
- Why Alzheimer trials fail: removing soluble oligomeric beta amyloid is essential, inconsistent, and difficult
- (2013) William I. Rosenblum NEUROBIOLOGY OF AGING
- Alzheimer’s disease: amino acid levels and brain metabolic status
- (2013) Maria Concetta Gueli et al. NEUROLOGICAL SCIENCES
- Metabolic profiling of Alzheimer's disease brains
- (2013) Koichi Inoue et al. Scientific Reports
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Astrocytes convert network excitation to tonic inhibition of neurons
- (2012) László Héja et al. BMC BIOLOGY
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- (2012) Wojciech Danysz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Reduced MTHFD1 Activity in Male Mice Perturbs Folate- and Choline-Dependent One-Carbon Metabolism as Well as Transsulfuration
- (2012) Martha S. Field et al. JOURNAL OF NUTRITION
- Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma
- (2012) Laura D. Gamble et al. Frontiers in Oncology
- Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts
- (2011) Lorna M Lopez et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The Baltimore Longitudinal Study of Aging (BLSA): A 50-Year-Long Journey and Plans for the Future
- (2011) L. Ferrucci JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- One-carbon metabolism and Alzheimer's disease: is it all a methylation matter?
- (2011) Andrea Fuso et al. NEUROBIOLOGY OF AGING
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- (2010) J.K. Ganjei DRUG NEWS & PERSPECTIVES
- Metabolomic Profiling of Anionic Metabolites by Capillary Electrophoresis Mass Spectrometry
- (2009) Tomoyoshi Soga et al. ANALYTICAL CHEMISTRY
- Memory performance is related to amyloid and tau pathology in the hippocampus
- (2009) C Reitz et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Polyamine Catabolism Is Enhanced after Traumatic Brain Injury
- (2009) Kamyar Zahedi et al. JOURNAL OF NEUROTRAUMA
- Effect of infarcts on dementia in the Baltimore longitudinal study of aging
- (2008) Juan C. Troncoso et al. ANNALS OF NEUROLOGY
- Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer’s disease
- (2008) Yi Li et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Depiction of metabolome changes in histidine-starvedEscherichia coliby CE-TOFMS
- (2007) Yoshiaki Ohashi et al. Molecular BioSystems
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