Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

Wnt signalling in neuronal differentiation and development

(2014) Nibaldo C. Inestrosa et al.   CELL AND TISSUE RESEARCH

Lifetime requirement of the methionine cycle for neuronal development and maintenance

(2014) Thomas B. Shea et al.   CURRENT OPINION IN PSYCHIATRY

In vivo Activation of Wnt Signaling Pathway Enhances Cognitive Function of Adult Mice and Reverses Cognitive Deficits in an Alzheimer's Disease Model

(2014) J. Y. Vargas et al.   JOURNAL OF NEUROSCIENCE

Hyperhomocysteinemia induced by methionine dietary nutritional overload modulates acetylcholinesterase activity in the rat brain

(2014) Dragan Hrnčić et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease

(2014) Chia-Chen Liu et al.   NEURON

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

(2013) Babak Hooshmand et al.   BRAIN

Canonical Wnt Signaling is Necessary for Object Recognition Memory Consolidation

(2013) A. M. Fortress et al.   JOURNAL OF NEUROSCIENCE

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

Nutritional essentiality of sulfur in health and disease

(2013) Yves Ingenbleek et al.   NUTRITION REVIEWS

A Reliable Way to Detect Endogenous Murine β-Amyloid

(2013) Andrew F. Teich et al.   PLoS One

WNT signaling in neuronal maturation and synaptogenesis

(2013) Silvana B. Rosso et al.   Frontiers in Cellular Neuroscience

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Three decades of Wnts: a personal perspective on how a scientific field developed

(2012) Roel Nusse et al.   EMBO JOURNAL

Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease

(2012) Elliott J. Mufson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid  -Mediated Synaptic Loss

(2012) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Long-Term Methionine Exposure Induces Memory Impairment on Inhibitory Avoidance Task and Alters Acetylcholinesterase Activity and Expression in Zebrafish (Danio rerio)

(2012) Fernanda Cenci Vuaden et al.   NEUROCHEMICAL RESEARCH

Wnt transmembrane signaling and long-term spatial memory

(2011) Nino Tabatadze et al.   HIPPOCAMPUS

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing

(2011) N C Inestrosa et al.   Translational Psychiatry

Genome-wide identification of new Wnt/β-catenin target genes in the human genome using CART method

(2010) Christian Hödar et al.   BMC GENOMICS

Red and Processed Meat Consumption and Risk of Incident Coronary Heart Disease, Stroke, and Diabetes Mellitus

(2010) Renata Micha et al.   CIRCULATION

Diet-Induced Hyperhomocysteinemia Increases Amyloid-β Formation and Deposition in a Mouse Model of Alzheimers Disease

(2010) J.-M. Zhuo et al.   Current Alzheimer Research

The role of Wnt signaling in neuroprotection

(2010) W. Cerpa et al.   DRUG NEWS & PERSPECTIVES

From trans-methylation to cytosine methylation: Evolution of the methylation hypothesis of schizophrenia

(2010) Dennis R. Grayson et al.   Epigenetics

Induction of Alzheimer’s-like changes in brain of mice expressing mutant APP fed excess methionine

(2010) Alexander McCampbell et al.   JOURNAL OF NEUROCHEMISTRY

L-methionine decreases dendritic spine density in mouse frontal cortex

(2010) Patricia Tueting et al.   NEUROREPORT

Hyperhomocysteinemia Increases β-Amyloid by Enhancing Expression of γ-Secretase and Phosphorylation of Amyloid Precursor Protein in Rat Brain

(2009) Chang-E Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular mechanisms of homocysteine toxicity

(2009) A. A. Boldyrev   BIOCHEMISTRY-MOSCOW

The Role of Methionine Oxidation/Reduction in the Regulation of Immune Response

(2009) Abdulbaki Agbas et al.   Current Signal Transduction Therapy

Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies

(2009) D. Aune et al.   DIABETOLOGIA

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/β-catenin signaling pathway

(2009) Macarena S. Arrázola et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease

(2009) E M Toledo et al.   MOLECULAR PSYCHIATRY

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

(2009) Lorena Varela-Nallar et al.   Neural Development

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits

(2008) Gonzalo I. Cancino et al.   BRAIN

Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain

(2008) A. V. Makhro et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Homocysteine activates calcium-mediated cell signaling mechanisms targeting the cytoskeleton in rat hippocampus

(2008) Samanta Oliveira Loureiro et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice

(2008) Andrea Fuso et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

(2008) Nibaldo C Inestrosa et al.   Molecular Neurodegeneration

Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats

(2008) Rajeshkumar U Koladiya et al.   BMC Pharmacology & Toxicology

Dietary methionine effects on plasma homocysteine and HDL metabolism in mice

(2007) Wanda Velez-Carrasco et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus

(2007) Chang-E. Zhang et al.   NEUROBIOLOGY OF AGING