Conformational changes in the Ebola virus membrane fusion machine induced by pH, Ca2+, and receptor binding

Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics

(2020) Natasha D. Durham et al.   Viruses-Basel

Direct Visualization of the Conformational Dynamics of Single Influenza Hemagglutinin Trimers

(2018) Dibyendu Kumar Das et al.   CELL

Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy

(2016) Ivana Nikić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1

(2016) Han Wang et al.   CELL

Toremifene interacts with and destabilizes the Ebola virus glycoprotein

(2016) Yuguang Zhao et al.   NATURE

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

(2016) Manuel F Juette et al.   NATURE METHODS

Feverish Quest for Ebola Immunotherapy: Straight or Cocktail?

(2016) Erica Ollmann Saphire et al.   TRENDS IN MICROBIOLOGY

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

(2016) Jennifer S. Spence et al.   mBio

Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

(2016) Ruben M. Markosyan et al.   PLoS Pathogens

Fluorescent biosensors illuminate calcium levels within defined beta-cell endosome subpopulations

(2015) Tobias Albrecht et al.   CELL CALCIUM

Ebolavirus Glycoprotein Directs Fusion through NPC1 + Endolysosomes

(2015) James A. Simmons et al.   JOURNAL OF VIROLOGY

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

(2015) Yasuteru Sakurai et al.   SCIENCE

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Ebola Virus Entry: A Curious and Complex Series of Events

(2015) Sven Moller-Tank et al.   PLoS Pathogens

Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1

(2014) Wolfgang H. Schmied et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

(2014) J. B. Munro et al.   SCIENCE

Rubella Virus: First Calcium-Requiring Viral Fusion Protein

(2014) Mathieu Dubé et al.   PLoS Pathogens

FDA-Approved Selective Estrogen Receptor Modulators Inhibit Ebola Virus Infection

(2013) L. M. Johansen et al.   Science Translational Medicine

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

(2012) Emily Happy Miller et al.   EMBO JOURNAL

Cathepsin Cleavage Potentiates the Ebola Virus Glycoprotein To Undergo a Subsequent Fusion-Relevant Conformational Change

(2011) M. Brecher et al.   JOURNAL OF VIROLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2

(2011) S. M. Gregory et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway

(2011) Nirupama Mulherkar et al.   VIROLOGY

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

(2010) Michael A. Whitt   JOURNAL OF VIROLOGICAL METHODS

Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes

(2010) Mohammad F. Saeed et al.   PLoS Pathogens

Ebolavirus Is Internalized into Host Cells via Macropinocytosis in a Viral Glycoprotein-Dependent Manner

(2010) Asuka Nanbo et al.   PLoS Pathogens

The Primed Ebolavirus Glycoprotein (19-Kilodalton GP1,2): Sequence and Residues Critical for Host Cell Binding

(2009) D. Dube et al.   JOURNAL OF VIROLOGY

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

(2008) Jeffrey E. Lee et al.   NATURE

Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation

(2008) I-M. Yu et al.   SCIENCE