Dihydroartemisinin Ameliorates Learning and Memory in Alzheimer’s Disease Through Promoting Autophagosome-Lysosome Fusion and Autolysosomal Degradation for Aβ Clearance

Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children

(2019) Palang Chotsiri et al.   Nature Communications

LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease

(2019) Bradlee L. Heckmann et al.   CELL

The Role of Autophagy in Alzheimer's Disease: Modeling and Simulations

(2018) MooYoung Choi et al.   BIOPHYSICAL JOURNAL

OUP accepted manuscript

(2018)   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Una revisión de los avances en la terapéutica de la enfermedad de Alzheimer: estrategia frente a la proteína β-amiloide

(2018) J. Folch et al.   NEUROLOGIA

Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes

(2018) Naoki Yamamoto et al.   NEUROSCIENCE

Artemisinin and its derivatives in treating helminthic infections beyond schistosomiasis

(2018) Nelson Siukei Lam et al.   PHARMACOLOGICAL RESEARCH

Pseudorabies virus induces autophagy to enhance viral replication in mouse neuro-2a cells in vitro

(2018) Changmeng Xu et al.   VIRUS RESEARCH

Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

(2018) Md. Sahab Uddin et al.   Frontiers in Aging Neuroscience

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

(2018) Frank Kloprogge et al.   PLOS MEDICINE

Population Pharmacokinetics of Artemether, Dihydroartemisinin, and Lumefantrine in Rwandese Pregnant Women Treated for Uncomplicated Plasmodium falciparum Malaria

(2018) Jesmin Lohy Das et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Implications of Autophagy in Alzheimer's Disease

(2018) Tadanori Hamano et al.   Current Alzheimer Research

Autophagic dysfunction in Alzheimer’s disease: Cellular and molecular mechanistic approaches to halt Alzheimer’s pathogenesis

(2018) Md. Sahab Uddin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Amyloid precursor protein and endosomal–lysosomal dysfunction in Alzheimer’s disease: inseparable partners in a multifactorial disease

(2017) Ralph A. Nixon   FASEB JOURNAL

An Intracellular Amyloid-β/AβPP Epitope Correlates with Neurodegeneration in those Neuronal Populations Early Involved in Alzheimer’s Disease

(2017) Gisela Esquerda-Canals et al.   JOURNAL OF ALZHEIMERS DISEASE

Autophagic flux control in neurodegeneration: Progress and precision targeting—Where do we stand?

(2017) Dumisile Lumkwana et al.   PROGRESS IN NEUROBIOLOGY

From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

(2017) Thomas Efferth   SEMINARS IN CANCER BIOLOGY

Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

(2017) Jesse S. Kerr et al.   TRENDS IN NEUROSCIENCES

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

(2017) Zili Zhang et al.   Cell Death & Disease

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

(2016) Inger Lauritzen et al.   ACTA NEUROPATHOLOGICA

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Alzheimer's disease genes and autophagy

(2016) Seung-Yong Yoon et al.   BRAIN RESEARCH

The Cellular Phase of Alzheimer’s Disease

(2016) Bart De Strooper et al.   CELL

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Autophagy-mediated Regulation of BACE1 Protein Trafficking and Degradation

(2016) Tuancheng Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Central Role for Phosphorylated p38α in Linking Proteasome Inhibition-Induced Apoptosis and Autophagy

(2016) Fang Guo et al.   MOLECULAR NEUROBIOLOGY

Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway

(2016) Tiejian Nie et al.   Cell Death & Disease

Dihydroartemisinin inhibits catabolism in rat chondrocytes by activating autophagy via inhibition of the NF-κB pathway

(2016) Li-Bo Jiang et al.   Scientific Reports

Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease

(2015) Yang Xiang et al.   ACTA NEUROPATHOLOGICA

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

(2015) Jiajie Diao et al.   NATURE

Clearance of amyloid β-protein and its role in the spreading of Alzheimer's disease pathology

(2015) Dietmar R. Thal   Frontiers in Aging Neuroscience

Does bafilomycin A1block the fusion of autophagosomes with lysosomes?

(2014) Daniel J. Klionsky et al.   Autophagy

Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes

(2014) Naoki Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Golgi defects enhance APP amyloidogenic processing in Alzheimer's disease

(2014) Gunjan Joshi et al.   BIOESSAYS

The activation of c-Jun NH2-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells

(2014) Guang Jia et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Protein recycling pathways in neurodegenerative diseases

(2014) Faisal Fecto et al.   Alzheimers Research & Therapy

Improvement of the efficacy of dihydroartemisinin with atorvastatin in an experimental cerebral malaria murine model

(2013) Jérôme Dormoi et al.   MALARIA JOURNAL

Ketamine reduces amyloid β-protein degradation by suppressing neprilysin expression in primary cultured astrocytes

(2013) Naoki Yamamoto et al.   NEUROSCIENCE LETTERS

Artemisinins: Pharmacological actions beyond anti-malarial

(2013) Wanxing Eugene Ho et al.   PHARMACOLOGY & THERAPEUTICS

Autophagy and apoptosis dysfunction in neurodegenerative disorders

(2013) Saeid Ghavami et al.   PROGRESS IN NEUROBIOLOGY

Involvement of hippocampal CAMKII/CREB signaling in the spatial memory retention induced by creatine

(2012) Mauren Assis Souza et al.   AMINO ACIDS

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system

(2012) Lin Zheng et al.   Translational Neurodegeneration

Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits

(2011) Smita Majumder et al.   PLoS One

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Autophagy in disease: a double-edged sword with therapeutic potential

(2009) Wim Martinet et al.   CLINICAL SCIENCE

Pharmacokinetics and Pharmacodynamics of Endoperoxide Antimalarials

(2009) Anirudh Gautam et al.   CURRENT DRUG METABOLISM

Pharmacokinetics, tissue distribution and mass balance of radiolabeled dihydroartemisinin in male rats

(2009) Lisa H Xie et al.   MALARIA JOURNAL

Protein misfolding and disease: from the test tube to the organism

(2008) Leila M Luheshi et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE