Double‐Layered M2e‐NA Protein Nanoparticle Immunization Induces Broad Cross‐Protection against Different Influenza Viruses in Mice

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages

(2019) Kizzmekia S. Corbett et al.   mBio

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

(2018) Yao-Qing Chen et al.   CELL

NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?

(2018) Florian Krammer et al.   mBio

Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses

(2018) Lei Deng et al.   Nature Communications

H7 Hemagglutinin nanoparticles retain immunogenicity after >3 months of 25°C storage

(2018) Timothy Z. Chang et al.   PLoS One

Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice

(2018) Lei Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiviral Activity of Fermented Ginseng Extracts against a Broad Range of Influenza Viruses

(2018) Ye Wang et al.   Viruses-Basel

Universal influenza vaccines: from viruses to nanoparticles

(2018) Ye Wang et al.   Expert Review of Vaccines

A Perspective on Nanoparticle Universal Influenza Vaccines

(2018) Lei Deng et al.   ACS Infectious Diseases

Nanoparticle Vaccines Against Infectious Diseases

(2018) Rashmirekha Pati et al.   Frontiers in Immunology

Evaluating the immunogenicity and safety of a BiondVax-developed universal influenza vaccine (Multimeric-001) either as a standalone vaccine or as a primer to H5N1 influenza vaccine

(2017) Eva van Doorn et al.   MEDICINE

Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

(2017) Madhusudan Rajendran et al.   mBio

Virus-Like Particle Vaccine Containing the F Protein of Respiratory Syncytial Virus Confers Protection without Pulmonary Disease by Modulating Specific Subsets of Dendritic Cells and Effector T Cells

(2015) Ki-Hye Kim et al.   JOURNAL OF VIROLOGY

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

(2015) Hadi M Yassine et al.   NATURE MEDICINE

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice

(2015) Teddy John Wohlbold et al.   mBio

Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers

(2015) Hongquan Wan et al.   Nature Communications

Biomaterials for Nanoparticle Vaccine Delivery Systems

(2014) Preety Sahdev et al.   PHARMACEUTICAL RESEARCH

Universal Influenza Vaccines, a Dream to Be Realized Soon

(2014) Han Zhang et al.   Viruses-Basel

Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses

(2013) Marija Zaric et al.   ACS Nano

Universal anti-neuraminidase antibody inhibiting all influenza A subtypes

(2013) Tracey M. Doyle et al.   ANTIVIRAL RESEARCH

The Universal Epitope of Influenza A Viral Neuraminidase Fundamentally Contributes to Enzyme Activity and Viral Replication

(2013) Tracey M. Doyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomewide Analysis of Reassortment and Evolution of Human Influenza A(H3N2) Viruses Circulating between 1968 and 2011

(2013) K. B. Westgeest et al.   JOURNAL OF VIROLOGY

Nanoclusters self-assembled from conformation-stabilized influenza M2e as broadly cross-protective influenza vaccines

(2013) Li Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanisms of Action of Adjuvants

(2013) Sunita Awate et al.   Frontiers in Immunology

Virus-like Particles Containing Multiple M2 Extracellular Domains Confer Improved Cross-protection Against Various Subtypes of Influenza Virus

(2012) Min-Chul Kim et al.   MOLECULAR THERAPY

A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A Virus

(2012) Chia-Ying Wu et al.   PLoS One

Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery

(2011) Zhiping Zhang et al.   BIOMATERIALS

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

A Generic System for the Expression and Purification of Soluble and Stable Influenza Neuraminidase

(2011) Peter M. Schmidt et al.   PLoS One

Microneedle Delivery of H5N1 Influenza Virus-Like Particles to the Skin Induces Long-Lasting B- and T-Cell Responses in Mice

(2010) J.-M. Song et al.   Clinical and Vaccine Immunology

Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins

(2010) Steven J. Gamblin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection

(2010) K. El Bakkouri et al.   JOURNAL OF IMMUNOLOGY

A Novel Influenza A (H1N1) Vaccine in Various Age Groups

(2009) Feng-Cai Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans

(2008) E. Assarsson et al.   JOURNAL OF VIROLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY