Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

Intestine‐on‐chip device increases ECM remodeling inducing faster epithelial cell differentiation

(2019) Vincenza De Gregorio et al.   BIOTECHNOLOGY AND BIOENGINEERING

Epimorphin Regulates the Intestinal Stem Cell Niche via Effects on the Stromal Microenvironment

(2018) Courtney E. Vishy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

3D stromal tissue equivalent affects intestinal epithelium morphogenesis in vitro

(2018) Vincenza De Gregorio et al.   BIOTECHNOLOGY AND BIOENGINEERING

Monitoring of erlotinib in pancreatic cancer patients during long-time administration and comparison to a physiologically based pharmacokinetic model

(2018) Andrea Gruber et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

(2018) Magdalena Kasendra et al.   Scientific Reports

Intestinal barrier dysfunction orchestrates the onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip

(2018) Woojung Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study

(2017) Panithi Sukho et al.   Stem Cell Reviews and Reports

Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study

(2017) Panithi Sukho et al.   Stem Cell Reviews and Reports

Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activity

(2017) Robert H. Berndsen et al.   Scientific Reports

Cancer-associated fibroblasts support vascular growth through mechanical force

(2017) Mary Kathryn Sewell-Loftin et al.   Scientific Reports

Fibroblasts and myofibroblasts of the intestinal lamina propria in physiology and disease

(2016) Manolis Roulis et al.   DIFFERENTIATION

Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development

(2016) Christopher R. Schlieve et al.   PLoS One

Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia

(2015) Leon Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Tissue underlying the intestinal epithelium elicits proliferation of intestinal stem cells following cytotoxic damage

(2015) Kristen M Seiler et al.   CELL AND TISSUE RESEARCH

Erlotinib-Cisplatin Combination Inhibits Growth and Angiogenesis through c-MYC and HIF-1α in EGFR-Mutated Lung Cancer In Vitro and In Vivo

(2015) Jasmine G. Lee et al.   NEOPLASIA

Enhanced anti-angiogenic effect of E7820 in combination with erlotinib in epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer xenograft models

(2014) Ken Ito et al.   CANCER SCIENCE

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays

(2014) Kelli L VanDussen et al.   GUT

Intestinal Subepithelial Myofibroblasts Support the Growth of Intestinal Epithelial Stem Cells

(2014) Nan Ye Lei et al.   PLoS One

Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

(2013) Daniel J. Nolan et al.   DEVELOPMENTAL CELL

In vitro models of angiogenesis and vasculogenesis in fibrin gel

(2013) Kristen T. Morin et al.   EXPERIMENTAL CELL RESEARCH

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids

(2013) Rebecca L. DiMarco et al.   Integrative Biology

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

(2013) C Moon et al.   Mucosal Immunology

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

(2013) Hiroyuki Miyoshi et al.   Nature Protocols

In Vitro Perfused Human Capillary Networks

(2013) Monica L. Moya et al.   TISSUE ENGINEERING PART C-METHODS

Pro-Angiogenic Activity of TLRs and NLRs: A Novel Link Between Gut Microbiota and Intestinal Angiogenesis

(2012) Anja Schirbel et al.   GASTROENTEROLOGY

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Intestinal myofibroblasts: targets for stem cell therapy

(2011) R. C. Mifflin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Coordinating cell behaviour during blood vessel formation

(2011) I. Geudens et al.   DEVELOPMENT

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

(2011) Andrew C. Newman et al.   MOLECULAR BIOLOGY OF THE CELL

A Computational Tool for Quantitative Analysis of Vascular Networks

(2011) Enrique Zudaire et al.   PLoS One

Intestinal Subepithelial Myofibroblasts Support in vitro and in vivo Growth of Human Small Intestinal Epithelium

(2011) Nicholas Lahar et al.   PLoS One

Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices

(2010) Kiana Aran et al.   LAB ON A CHIP

Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection

(2010) Mark E. McMellen et al.   SURGERY

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Intestinal resection induces angiogenesis within adapting intestinal villi

(2009) Colin A. Martin et al.   JOURNAL OF PEDIATRIC SURGERY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Rapid Anastomosis of Endothelial Progenitor Cell–Derived Vessels with Host Vasculature Is Promoted by a High Density of Cotransplanted Fibroblasts

(2009) Xiaofang Chen et al.   TISSUE ENGINEERING PART A

Endothelial???stromal interactions in angiogenesis

(2008) Christopher CW Hughes   CURRENT OPINION IN HEMATOLOGY

Functional Tissue-Engineered Valves from Cell-Remodeled Fibrin with Commissural Alignment of Cell-Produced Collagen

(2008) Paul S. Robinson et al.   TISSUE ENGINEERING PART A