A universal reporter cell line for bioactivity evaluation of engineered cytokine products
Published 2020 View Full Article
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Title
A universal reporter cell line for bioactivity evaluation of engineered cytokine products
Authors
Keywords
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Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-02-24
DOI
10.1038/s41598-020-60182-4
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- (2018) Aruna Bitra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
- (2018) Marta Compte et al. Nature Communications
- DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated
- (2017) Maria Carmen Mulero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling
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- (2017) Ajithkumar Vasanthakumar et al. Cell Reports
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- (2016) Dario Neri et al. CURRENT OPINION IN IMMUNOLOGY
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- (2016) Erika M. Cook et al. JOURNAL OF IMMUNOLOGY
- Application potential of toll-like receptors in cancer immunotherapy
- (2016) Ming Shi et al. MEDICINE
- A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface
- (2016) Rob N. de Jong et al. PLOS BIOLOGY
- Advancing targeted co-stimulation with antibody-fusion proteins by introducing TNF superfamily members in a single-chain format
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- (2014) David A Schaer et al. Journal for ImmunoTherapy of Cancer
- The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity
- (2013) T Hemmerle et al. BRITISH JOURNAL OF CANCER
- Evaluating combinations of costimulatory antibody–ligand fusion proteins for targeted cancer immunotherapy
- (2013) Nora Hornig et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- A new platform for constructing antibody-cytokine fusion proteins (immunocytokines) with improved biological properties and adaptable cytokine activity
- (2013) S. D. Gillies PROTEIN ENGINEERING DESIGN & SELECTION
- The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel
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- (2008) Alessandra Villa et al. INTERNATIONAL JOURNAL OF CANCER
- Structural basis for ligand-mediated mouse GITR activation
- (2008) Z. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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