Evaluating combinations of costimulatory antibody–ligand fusion proteins for targeted cancer immunotherapy

An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas

(2012) K. A. Murphy et al.   CLINICAL CANCER RESEARCH

Modulation of GITR for cancer immunotherapy

(2012) David A Schaer et al.   CURRENT OPINION IN IMMUNOLOGY

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

(2012) Suzanne L Topalian et al.   CURRENT OPINION IN IMMUNOLOGY

Immunotherapy earns its spot in the ranks of cancer therapy

(2012) Drew Pardoll et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Combination of a Bispecific Antibody and Costimulatory Antibody-Ligand Fusion Proteins for Targeted Cancer Immunotherapy

(2012) Nora Hornig et al.   JOURNAL OF IMMUNOTHERAPY

Chemokines, costimulatory molecules and fusion proteins for the immunotherapy of solid tumors

(2011) Melissa G Lechner et al.   Immunotherapy

Combination CTLA-4 Blockade and 4-1BB Activation Enhances Tumor Rejection by Increasing T-Cell Infiltration, Proliferation, and Cytokine Production

(2011) Michael A. Curran et al.   PLoS One

Soluble multi-trimeric TNF superfamily ligand adjuvants enhance immune responses to a HIV-1 Gag DNA vaccine

(2011) Saravana K. Kanagavelu et al.   VACCINE

4-1BB Ligand as an Effective Multifunctional Immunomodulator and Antigen Delivery Vehicle for the Development of Therapeutic Cancer Vaccines

(2010) R. K. Sharma et al.   CANCER RESEARCH

Triple expression of B7-1, B7-2 and 4-1BBL enhanced antitumor immune response against mouse H22 hepatocellular carcinoma

(2010) Guoqiang Li et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Combination Therapy of Established Tumors by Antibodies Targeting Immune Activating and Suppressing Molecules

(2010) K. Takeda et al.   JOURNAL OF IMMUNOLOGY

Efficient Inhibition of Human B-cell Lymphoma in SCID Mice by Synergistic Antitumor Effect of Human 4-1BB Ligand/Anti-CD20 Fusion Proteins and Anti-CD3/Anti-CD20 Diabodies

(2010) Rong Liu et al.   JOURNAL OF IMMUNOTHERAPY

Tumor-specific Crosslinking of GITR as Costimulation for Immunotherapy

(2010) Tanja Burckhart et al.   JOURNAL OF IMMUNOTHERAPY

Clinical Experiences With Anti-CD137 and Anti-PD1 Therapeutic Antibodies

(2010) Paolo A. Ascierto et al.   SEMINARS IN ONCOLOGY

4-1BBL costimulation retrieves CD28 expression in activated T cells

(2009) Mojtaba Habib-Agahi et al.   CELLULAR IMMUNOLOGY

Palettes of Vaccines and Immunostimulatory Monoclonal Antibodies for Combination

(2009) I. Melero et al.   CLINICAL CANCER RESEARCH

Targeted Cancer Immunotherapy Using Ligands of the Tumor Necrosis Factor Super-Family

(2009) E. Bremer et al.   CURRENT DRUG TARGETS

Sequence, structure, function, immunity: structural genomics of costimulation

(2009) Kausik Chattopadhyay et al.   IMMUNOLOGICAL REVIEWS

Costimulatory and coinhibitory receptors in anti-tumor immunity

(2009) Gregory Driessens et al.   IMMUNOLOGICAL REVIEWS

Trimer Stabilization, Oligomerization, and Antibody-Mediated Cell Surface Immobilization Improve the Activity of Soluble Trimers of CD27L, CD40L, 41BBL, and Glucocorticoid-Induced TNF Receptor Ligand

(2009) A. Wyzgol et al.   JOURNAL OF IMMUNOLOGY

The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells

(2008) Johanna Kober et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Activity of soluble OX40 ligand is enhanced by oligomerization and cell surface immobilization

(2008) Nicole Müller et al.   FEBS Journal

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways

(2008) Brian T. Fife et al.   IMMUNOLOGICAL REVIEWS

Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice

(2008) Dafne Müller et al.   JOURNAL OF IMMUNOLOGICAL METHODS