Increased Adiposity Enhances the Accumulation of MDSCs in the Tumor Microenvironment and Adipose Tissue of Pancreatic Tumor-Bearing Mice and in Immune Organs of Tumor-Free Hosts

Obesity and Risk for Second Malignant Neoplasms in Childhood Cancer Survivors: A Case-Control Study Utilizing the California Cancer Registry

(2019) Diana J Moke et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Physical Activity Plus Energy Restriction Prevents 4T1.2 Mammary Tumor Progression, MDSC Accumulation, and an Immunosuppressive Tumor Microenvironment

(2019) William J. Turbitt et al.   Cancer Prevention Research

Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer

(2019) Peiwen Ma et al.   Frontiers in Immunology

Cancer, obesity and immunometabolism – Connecting the dots

(2018) Lydia Dyck et al.   CANCER LETTERS

Myeloid derived-suppressor cells: their role in cancer and obesity

(2018) Suzanne Ostrand-Rosenberg   CURRENT OPINION IN IMMUNOLOGY

Obesity induced T cell dysfunction and implications for cancer immunotherapy

(2018) Ethan G Aguilar et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy

(2018) Jinyang Li et al.   IMMUNITY

Trends in Obesity and Severe Obesity Prevalence in US Youth and Adults by Sex and Age, 2007-2008 to 2015-2016

(2018) Craig M. Hales et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Myeloid-derived suppressor cells coming of age

(2018) Filippo Veglia et al.   NATURE IMMUNOLOGY

Properties and functions of adipose tissue macrophages in obesity

(2018) Lucia Russo et al.   IMMUNOLOGY

Energy Restriction and Exercise Differentially Enhance Components of Systemic and Mucosal Immunity in Mice

(2018) Connie J. Rogers et al.   JOURNAL OF NUTRITION

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

(2018) Xavier Michelet et al.   NATURE IMMUNOLOGY

The obese adipose tissue microenvironment in cancer development and progression

(2018) Daniela F. Quail et al.   Nature Reviews Endocrinology

Suppression of T cells by myeloid-derived suppressor cells in cancer

(2017) Jieying Chen et al.   HUMAN IMMUNOLOGY

Myeloid suppressor cells in cancer and autoimmunity

(2017) Antonio Sica et al.   JOURNAL OF AUTOIMMUNITY

Emerging Concepts Linking Obesity with the Hallmarks of Cancer

(2017) Claire L. Donohoe et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

T-cell Localization, Activation, and Clonal Expansion in Human Pancreatic Ductal Adenocarcinoma

(2017) Ingunn M. Stromnes et al.   Cancer Immunology Research

Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity — United States, 2005–2014

(2017) C. Brooke Steele et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

(2017) Susanne M. Steggerda et al.   Journal for ImmunoTherapy of Cancer

Myeloid-derived suppressor cells and their role in pancreatic cancer

(2016) M Pergamo et al.   CANCER GENE THERAPY

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity

(2016) J. Incio et al.   CLINICAL CANCER RESEARCH

Premorbid Obesity and Mortality in Patients With Pancreatic Cancer: A Systematic Review and Meta-analysis

(2016) Kaustav Majumder et al.   Clinical Gastroenterology and Hepatology

Body Fatness and Cancer — Viewpoint of the IARC Working Group

(2016) Béatrice Lauby-Secretan et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy

(2016) J. Incio et al.   Cancer Discovery

Circulating Leptin and Risk of Pancreatic Cancer: A Pooled Analysis From 3 Cohorts

(2015) Rachael Z. Stolzenberg-Solomon et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Central adiposity, obesity during early adulthood, and pancreatic cancer mortality in a pooled analysis of cohort studies

(2015) J. M. Genkinger et al.   ANNALS OF ONCOLOGY

Global Cancer Incidence and Mortality Rates and Trends--An Update

(2015) L. A. Torre et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Fish Oil Enhances T Cell Function and Tumor Infiltration and Is Correlated With a Cancer Prevention Effect in HER-2/neu But Not PyMT Transgenic Mice

(2015) William J. Turbitt et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Modulation of the Leptin Receptor Mediates Tumor Growth and Migration of Pancreatic Cancer Cells

(2015) Alisha M. Mendonsa et al.   PLoS One

Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2

(2015) Malika Hale et al.   PLoS One

Body mass index and survival in women with breast cancer—systematic literature review and meta-analysis of 82 follow-up studies

(2014) D. S. M. Chan et al.   ANNALS OF ONCOLOGY

Patients with pancreatic adenocarcinoma exhibit elevated levels of myeloid-derived suppressor cells upon progression of disease

(2014) Joseph Markowitz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Predictors of being overweight or obese in survivors of pediatric acute lymphoblastic leukemia (ALL)

(2014) Fang Fang Zhang et al.   PEDIATRIC BLOOD & CANCER

Increased Levels of Granulocytic Myeloid-Derived Suppressor Cells in Peripheral Blood and Tumour Tissue of Pancreatic Cancer Patients

(2014) Yazan S. Khaled et al.   Journal of Immunology Research

Dietary Energy Balance Modulation of Kras- and Ink4a/Arf+/--Driven Pancreatic Cancer: The Role of Insulin-like Growth Factor-I

(2013) L. M. Lashinger et al.   Cancer Prevention Research

Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner

(2013) T. A. Mace et al.   CANCER RESEARCH

Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells

(2013) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

The S100A8/A9 complex reduces CTLA4 expression by immature myeloid cells

(2013) Daniela Basso et al.   OncoImmunology

Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

(2012) Matthew R. Porembka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Obesity, But Not High-Fat Diet, Promotes Murine Pancreatic Cancer Growth

(2012) Patrick B. White et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13

(2011) Rachel F. Gabitass et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Gr-1+CD11b+Myeloid-derived Suppressor Cells Suppress Inflammation and Promote Insulin Sensitivity in Obesity

(2011) Sheng Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anthropometric Measures, Body Mass Index, and Pancreatic Cancer

(2010) Alan A. Arslan   ARCHIVES OF INTERNAL MEDICINE

Obesity adversely affects survival in pancreatic cancer patients

(2010) Robert R. McWilliams et al.   CANCER

Body mass index and blood pressure changes over the course of treatment of pediatric acute lymphoblastic leukemia

(2010) Adam J. Esbenshade et al.   PEDIATRIC BLOOD & CANCER

The Antitumor and Immunoadjuvant Effects of IFN-  in Combination with Recombinant Poxvirus Vaccines

(2009) K. W. Hance et al.   CLINICAL CANCER RESEARCH

Second Neoplasms in Survivors of Childhood Cancer: Findings From the Childhood Cancer Survivor Study Cohort

(2009) Anna T. Meadows et al.   JOURNAL OF CLINICAL ONCOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961

(2009) Janice S. Withycombe et al.   PEDIATRIC BLOOD & CANCER

Obesity potentiates the growth and dissemination of pancreatic cancer

(2009) Nicholas J. Zyromski et al.   SURGERY

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Exercise enhances vaccine-induced antigen-specific T cell responses

(2008) Connie J. Rogers et al.   VACCINE