Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-19
DOI
10.1038/s41467-019-13621-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a
- (2019) Wei Liu et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- RNAi assisted genome evolution unveils yeast mutants with improved xylose utilization
- (2018) Mohammad HamediRad et al. BIOTECHNOLOGY AND BIOENGINEERING
- Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System
- (2018) Jiazhang Lian et al. Biotechnology Journal
- An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
- (2018) Assaf C. Bester et al. CELL
- Recent advances in metabolic engineering of Saccharomyces cerevisiae : New tools and their applications
- (2018) Jiazhang Lian et al. METABOLIC ENGINEERING
- Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision
- (2018) Zehua Bao et al. NATURE BIOTECHNOLOGY
- Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance
- (2018) Tianmin Wang et al. Nature Communications
- Advancing Metabolic Engineering of Saccharomyces cerevisiae Using the CRISPR/Cas System
- (2018) Jiazhang Lian et al. Biotechnology Journal
- Engineering biological systems using automated biofoundries
- (2017) Ran Chao et al. METABOLIC ENGINEERING
- Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
- (2017) Julia Joung et al. Nature Protocols
- Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
- (2017) Jiazhang Lian et al. Nature Communications
- Automated multiplex genome-scale engineering in yeast
- (2017) Tong Si et al. Nature Communications
- Enabling Graded and Large-Scale Multiplex of Desired Genes Using a Dual-Mode dCas9 Activator in Saccharomyces cerevisiae
- (2017) Matthew Deaner et al. ACS Synthetic Biology
- Engineering Cellular Metabolism
- (2016) Jens Nielsen et al. CELL
- Misregulation of a DDHD Domain-containing Lipase Causes Mitochondrial Dysfunction in Yeast
- (2016) Pradeep Kumar Yadav et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering
- (2016) Andrew D Garst et al. NATURE BIOTECHNOLOGY
- CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering
- (2016) Kornel Labun et al. NUCLEIC ACIDS RESEARCH
- CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
- (2016) S. John Liu et al. SCIENCE
- N-hypermannose glycosylation disruption enhances recombinant protein production by regulating secretory pathway and cell wall integrity in Saccharomyces cerevisiae
- (2016) Hongting Tang et al. Scientific Reports
- Metabolic engineering of Saccharomyces cerevisiae for improvement in stresses tolerance
- (2016) Nileema R. Divate et al. Bioengineered
- Rapid prototyping of microbial cell factories via genome-scale engineering
- (2015) Tong Si et al. BIOTECHNOLOGY ADVANCES
- Design and engineering of intracellular-metabolite-sensing/regulation gene circuits inSaccharomyces cerevisiae
- (2015) Meng Wang et al. BIOTECHNOLOGY AND BIOENGINEERING
- Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
- (2015) Jesse G. Zalatan et al. CELL
- Protein N-terminal Acetylation by the NatA Complex Is Critical for Selective Mitochondrial Degradation
- (2015) Akinori Eiyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease
- (2015) James E Dahlman et al. NATURE BIOTECHNOLOGY
- Cas9 gRNA engineering for genome editing, activation and repression
- (2015) Samira Kiani et al. NATURE METHODS
- High-throughput functional genomics using CRISPR–Cas9
- (2015) Ophir Shalem et al. NATURE REVIEWS GENETICS
- Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast
- (2015) Mingtao Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of a Synthetic Malonyl-CoA Sensor in Saccharomyces cerevisiae for Intracellular Metabolite Monitoring and Genetic Screening
- (2015) Sijin Li et al. ACS Synthetic Biology
- Genome-wide RNAi screen reveals the E3 SUMO-protein ligase gene SIZ1 as a novel determinant of furfural tolerance in Saccharomyces cerevisiae
- (2014) Han Xiao et al. Biotechnology for Biofuels
- Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation
- (2014) Luke A. Gilbert et al. CELL
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Activation of the mitochondrial signaling pathway in response to organic solvent stress in yeast
- (2014) Nao Nishida-Aoki et al. CURRENT GENETICS
- CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
- (2014) Tessa G. Montague et al. NUCLEIC ACIDS RESEARCH
- Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae
- (2014) Zehua Bao et al. ACS Synthetic Biology
- Genome-scale engineering for systems and synthetic biology
- (2013) K. M. Esvelt et al. Molecular Systems Biology
- Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
- (2013) Kevin M Esvelt et al. NATURE METHODS
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Rcf1 Mediates Cytochrome Oxidase Assembly and Respirasome Formation, Revealing Heterogeneity of the Enzyme Complex
- (2012) Milena Vukotic et al. Cell Metabolism
- Microbial production of indolylglucosinolate through engineering of a multi-gene pathway in a versatile yeast expression platform
- (2012) Michael Dalgaard Mikkelsen et al. METABOLIC ENGINEERING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation