Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice

Antitumor and Apoptosis-inducing Effects of Piperine on Human Melanoma Cells

(2019) EUN SEON YOO et al.   ANTICANCER RESEARCH

T-bet deficiency attenuates cardiac remodelling in rats

(2018) Zhen-Guo Ma et al.   BASIC RESEARCH IN CARDIOLOGY

A77 1726 (leflunomide) blocks and reverses cardiac hypertrophy and fibrosis in mice

(2018) Zhen-Guo Ma et al.   CLINICAL SCIENCE

CTRP3 protected against doxorubicin-induced cardiac dysfunction, inflammation and cell death via activation of Sirt1

(2018) Yu-Pei Yuan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Downregulation of miR-130a, antagonized doxorubicin-induced cardiotoxicity via increasing the PPARγ expression in mESCs-derived cardiac cells

(2018) Golnaz Pakravan et al.   Cell Death & Disease

C1q-tumour necrosis factor-related protein-3 exacerbates cardiac hypertrophy in mice

(2018) Zhen-Guo Ma et al.   CARDIOVASCULAR RESEARCH

Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia

(2017) Chen Wang-sheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis

(2017) Shiyan Peng et al.   Oxidative Medicine and Cellular Longevity

Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

(2017) Zhen-Guo Ma et al.   EBioMedicine

Piperine Suppresses Pyroptosis and Interleukin-1β Release upon ATP Triggering and Bacterial Infection

(2016) Yi-Dan Liang et al.   Frontiers in Pharmacology

Effects of pioglitazone on cardiac and adipose tissue pathology in rats with metabolic syndrome

(2015) Natsumi Matsuura et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Rosiglitazone, a PPARγagonist, ameliorates palmitate-induced insulin resistance and apoptosis in skeletal muscle cells

(2014) Reza Meshkani et al.   CELL BIOCHEMISTRY AND FUNCTION

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Prevention of Anthracycline-Induced Cardiotoxicity

(2014) Pimprapa Vejpongsa et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Piper nigrumand Piperine: An Update

(2013) Murlidhar Meghwal et al.   PHYTOTHERAPY RESEARCH

Doxorubicin treatment inhibits PPARγ and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models

(2012) Sankarganesh Arunachalam et al.   FEBS LETTERS

Peroxisome Proliferator-Activated Receptor-γ Activation With Angiotensin II Type 1 Receptor Blockade Is Pivotal for the Prevention of Blood-Brain Barrier Impairment and Cognitive Decline in Type 2 Diabetic Mice

(2012) Li-Juan Min et al.   HYPERTENSION

Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation

(2010) Masanori Konishi et al.   CARDIOVASCULAR RESEARCH

Inhibition of lipopolysaccharide-induced inflammatory responses by piperine

(2010) Gi-Sang Bae et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

Heat Shock Protein 20 Interacting With Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity

(2008) Guo-Chang Fan et al.   CIRCULATION RESEARCH

Dissociation of antihyperglycaemic and adverse effects of partial perioxisome proliferator-activated receptor (PPAR-γ) agonist balaglitazone

(2008) Philip J. Larsen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY