Hypoxia-induced lncRNA PDIA3P1 promotes mesenchymal transition via sponging of miR-124-3p in glioma

The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma

(2019) Vivek Bhaskaran et al.   Nature Communications

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

(2019) Junfei Zhao et al.   NATURE MEDICINE

The landscape of the mesenchymal signature in brain tumours

(2019) Jinan Behnan et al.   BRAIN

Genetic and molecular epidemiology of adult diffuse glioma

(2019) Annette M. Molinaro et al.   Nature Reviews Neurology

Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways

(2019) Mingyu Qian et al.   ONCOGENE

miRNA-124-3p/neuropilin-1(NRP-1) axis plays an important role in mediating glioblastoma growth and angiogenesis

(2018) Guilong Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

(2018) Xirui Liu et al.   Molecular Cancer

Current state of immunotherapy for glioblastoma

(2018) Michael Lim et al.   Nature Reviews Clinical Oncology

Towards a complete map of the human long non-coding RNA transcriptome

(2018) Barbara Uszczynska-Ratajczak et al.   NATURE REVIEWS GENETICS

Immunosuppressive effects of hypoxia-induced glioma exosomes through myeloid-derived suppressor cells via the miR-10a/Rora and miR-21/Pten Pathways

(2018) Xiaofan Guo et al.   ONCOGENE

Primary brain tumours in adults

(2018) Sarah Lapointe et al.   LANCET

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma

(2018) Tianrun Liu et al.   Nature Communications

Role of Pseudogenes in Tumorigenesis

(2018) Xinling Hu et al.   Cancers

NF-κB, Mesenchymal Differentiation and Glioblastoma

(2018) Bakhtiar Yamini   Cells

TAGLN2 is a candidate prognostic biomarker promoting tumorigenesis in human gliomas

(2017) Ming-Zhi Han et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to hyperactivate AKT and confer resistance to AKT inhibitors

(2017) Aifu Lin et al.   NATURE CELL BIOLOGY

Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

(2017) Xun Jin et al.   NATURE MEDICINE

Hypoxia in the glioblastoma microenvironment: shaping the phenotype of cancer stem-like cells

(2017) Nicole Colwell et al.   NEURO-ONCOLOGY

The New RNA World: Growing Evidence for Long Noncoding RNA Functionality

(2017) Allison Jandura et al.   TRENDS IN GENETICS

GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma

(2017) Marta Moreno et al.   Cell Reports

The lncRNA PDIA3P Interacts with miR-185-5p to Modulate Oral Squamous Cell Carcinoma Progression by Targeting Cyclin D2

(2017) Cheng-Cao Sun et al.   Molecular Therapy-Nucleic Acids

lncTCF7 is a negative prognostic factor, and knockdown of lncTCF7 inhibits migration, proliferation and tumorigenicity in glioma

(2017) Xiao Gao et al.   Scientific Reports

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner

(2016) Sung-Hak Kim et al.   CANCER CELL

MiR-124-3p/B4GALT1 axis plays an important role in SOCS3-regulated growth and chemo-sensitivity of CML

(2016) Yu-xiao Liu et al.   Journal of Hematology & Oncology

Endogenous microRNA sponges: evidence and controversy

(2016) Daniel W. Thomson et al.   NATURE REVIEWS GENETICS

Targeting NF- B in glioblastoma: A therapeutic approach

(2016) D. Friedmann-Morvinski et al.   Science Advances

The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo

(2015) Florian A. Karreth et al.   CELL

Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma

(2015) Cheolhee Won et al.   HEPATOLOGY

Long Noncoding RNAs in Cell-Fate Programming and Reprogramming

(2014) Ryan A. Flynn et al.   Cell Stem Cell

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin’s B lymphomas via NF-κB-dependent induction of HIF-1α

(2014) J Chiche et al.   LEUKEMIA

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma

(2013) Yingjian Liang et al.   HEPATOLOGY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

(2012) Y. Piao et al.   NEURO-ONCOLOGY

Epigenetic Regulation by Long Noncoding RNAs

(2012) J. T. Lee   SCIENCE

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies

(2011) Yin Wang et al.   Cell Stem Cell

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

(2010) Bart van de Sluis et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE