E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα

Molecular Pathways: Current Role and Future Directions of the Retinoic Acid Pathway in Cancer Prevention and Treatment

(2013) R. M. Connolly et al.   CLINICAL CANCER RESEARCH

Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing’s sarcoma

(2013) Xing Dai et al.   MEDICAL SCIENCE MONITOR

Retinoic acid regulates commitment of undifferentiated mesenchymal stem cells into osteoblasts and adipocytes

(2012) Kunihiro Hisada et al.   JOURNAL OF BONE AND MINERAL METABOLISM

TheMEToncogene transforms human primary bone-derived cells into osteosarcomas by targeting committed osteo-progenitors

(2012) Nadia Dani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

p38αMAPK interacts with and inhibits RARα: suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells

(2012) M Gianni et al.   LEUKEMIA

Bortezomib Sensitizes Human Acute Myeloid Leukemia Cells to All-Trans-Retinoic Acid-Induced Differentiation by Modifying the RAR /STAT1 Axis

(2012) M. Ying et al.   MOLECULAR CANCER THERAPEUTICS

Gene Expression Profiling Combined with Bioinformatics Analysis Identify Biomarkers for Parkinson Disease

(2012) Hongyu Diao et al.   PLoS One

Retinoic acid-induced Smad3 expression is required for the induction of osteoblastogenesis of mesenchymal stem cells

(2011) Molly Dingwall et al.   DIFFERENTIATION

Cyr61 expression in osteosarcoma indicates poor prognosis and promotes intratibial growth and lung metastasis in mice

(2011) Adam A Sabile et al.   JOURNAL OF BONE AND MINERAL RESEARCH

E2F1-dependent oncogenic addiction of melanoma cells to MDM2

(2011) M Verhaegen et al.   ONCOGENE

Inhibition of all-Trans-retinoic acid-induced proteasome activation potentiates the differentiating effect of retinoid in acute myeloid leukemia cells

(2010) Yanfen Fang et al.   MOLECULAR CARCINOGENESIS

Retinoid-suppressed phosphorylation of RARα mediates the differentiation pathway of osteosarcoma cells

(2010) P Luo et al.   ONCOGENE

Deregulated expression of E2F1 promotes proteolytic degradation of tumor suppressor p73 and inhibits its transcriptional activity

(2009) Toshinori Ozaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells

(2009) Ji Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of E2F1-induced Apoptosis by the Nucleolar Protein RRP1B

(2009) Jason C. Paik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss ofCdkn2

(2009) Alexander B Mohseny et al.   JOURNAL OF PATHOLOGY

Restriction of retinoic acid activity by Cyp26b1 is required for proper timing and patterning of osteogenesis during zebrafish development

(2008) K. Laue et al.   DEVELOPMENT

Differentiation of Osteoblasts and Osteocytes from Mesenchymal Stem Cells

(2008) Terhi Heino et al.   Current Stem Cell Research & Therapy