Targeting protein geranylgeranylation slows tumor development in a murine model of prostate cancer metastasis

Targeting geranylgeranylation reduces adrenal gland tumor burden in a murine model of prostate cancer metastasis

(2015) Jacqueline E. Reilly et al.   CLINICAL & EXPERIMENTAL METASTASIS

MiR-203 down-regulates Rap1A and suppresses cell proliferation, adhesion and invasion in prostate cancer

(2015) Jun Xiang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Functional Cross-talk between Ras and Rho Pathways

(2014) Mamta Jaiswal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mevalonate metabolism in cancer and immune cells

(2013) Martin Thurnher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial

(2013) Olöf Bjarnadottir et al.   BREAST CANCER RESEARCH AND TREATMENT

Apocynin, an NADPH oxidase inhibitor, suppresses progression of prostate cancer via Rac1 dephosphorylation

(2013) Shugo Suzuki et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Bisphosphonates in the Adjuvant Setting of Breast Cancer Therapy—Effect on Survival: A Systematic Review and Meta-Analysis

(2013) Irit Ben-Aharon et al.   PLoS One

Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases

(2013) Y Zhu et al.   Cell Death & Disease

Vav3-Rac1 Signaling Regulates Prostate Cancer Metastasis with Elevated Vav3 Expression Correlating with Prostate Cancer Progression and Posttreatment Recurrence

(2012) K.-T. Lin et al.   CANCER RESEARCH

Statins, autophagy and cancer metastasis

(2012) Jing Zhang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Bisphosphonates: The first 40years

(2011) R. Graham G. Russell   BONE

The diverse roles of Rac signaling in tumorigenesis

(2011) Natalie A. Mack et al.   CELL CYCLE

Bisphosphonates Induce Autophagy by Depleting Geranylgeranyl Diphosphate

(2011) B. M. Wasko et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration

(2010) Amel Dudakovic et al.   INVESTIGATIONAL NEW DRUGS

Activation of Rac1 Is Closely Related to Androgen-Independent Cell Proliferation of Prostate Cancer Cells Bothin Vitroandin Vivo

(2010) Takashi Kobayashi et al.   MOLECULAR ENDOCRINOLOGY

Activation of Rap1 Promotes Prostate Cancer Metastasis

(2009) C. L. Bailey et al.   CANCER RESEARCH

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy

(2008) Michael Gnant et al.   LANCET ONCOLOGY

Ligand-Independent Activation of Androgen Receptors by Rho GTPase Signaling in Prostate Cancer

(2007) Leah S. Lyons et al.   MOLECULAR ENDOCRINOLOGY