Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration

The Intermediate Enzymes of Isoprenoid Metabolism as Anticancer Targets

(2012) Andrew Wiemer et al.   Anti-Cancer Agents in Medicinal Chemistry

Pharmacologic Inhibition of Squalene Synthase and Other Downstream Enzymes of the Cholesterol Synthesis Pathway

(2009) Stephanie Seiki et al.   Cardiology in Review

Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation

(2009) Yonghui Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Determination of Geranyl Diphosphate Levels in Cultured Human Cells

(2009) Sarah A. Holstein et al.   LIPIDS

Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27Kip1 Phosphorylation on Thr187 and Accumulates p27Kip1 in the Nucleus: Implications for Breast Cancer Therapy

(2009) A. Kazi et al.   MOLECULAR AND CELLULAR BIOLOGY

Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue

(2008) Huaxiang Tong et al.   ANALYTICAL BIOCHEMISTRY

Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation

(2008) Andrew J. Wiemer et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mono- and dialkyl isoprenoid bisphosphonates as geranylgeranyl diphosphate synthase inhibitors

(2007) Andrew J. Wiemer et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Role of Rho GTPases in breast cancer

(2007) Yong Tang   Frontiers in Bioscience-Landmark