Mitochondrial DNA promotes autoimmunity

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

(2020) Jeonghan Kim et al.   SCIENCE

Type I IFN expression is stimulated by cytosolic Mt DNA released from pneumolysin‐damaged mitochondria via the STING signaling pathway in macrophages

(2019) Xuexue Hu et al.   FEBS Journal

DNA sensing by the cGAS–STING pathway in health and disease

(2019) Mona Motwani et al.   NATURE REVIEWS GENETICS

APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore

(2019) Shrijal S. Shah et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Redox-dependent gating of VDAC by mitoNEET

(2019) Colin H. Lipper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BAX and BAK at the Gates of Innate Immunity

(2018) Lorenzo Galluzzi et al.   TRENDS IN CELL BIOLOGY

Type I Interferons in Autoimmune Disease

(2018) Mary K. Crow et al.   Annual Review of Pathology-Mechanisms of Disease

Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing

(2013) Nadine Gehrke et al.   IMMUNITY