Structures of the AMPA receptor in complex with its auxiliary subunit cornichon

Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8

(2019) Beatriz Herguedas et al.   SCIENCE

CORNICHON sorting and regulation of GLR channels underlie pollen tube Ca2+homeostasis

(2018) Michael M. Wudick et al.   SCIENCE

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

GABAA receptor signalling mechanisms revealed by structural pharmacology

(2018) Simonas Masiulis et al.   NATURE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation

(2017) Joshua Traynelis et al.   GENOME RESEARCH

Engineering defined membrane-embedded elements of AMPA receptor induces opposing gating modulation by cornichon 3 and stargazin

(2017) Natalie M. Hawken et al.   JOURNAL OF PHYSIOLOGY-LONDON

Channel opening and gating mechanism in AMPA-subtype glutamate receptors

(2017) Edward C. Twomey et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes

(2017) Edward C. Twomey et al.   NEURON

Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM

(2016) Yan Zhao et al.   NATURE

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

(2016) Nami Tajima et al.   NATURE

Structure and organization of heteromeric AMPA-type glutamate receptors

(2016) Beatriz Herguedas et al.   SCIENCE

GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons

(2016) Xinglong Gu et al.   Nature Communications

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

JPred4: a protein secondary structure prediction server

(2015) Alexey Drozdetskiy et al.   NUCLEIC ACIDS RESEARCH

Molecular Dissection of the Interaction between the AMPA Receptor and Cornichon Homolog-3

(2014) N. F. Shanks et al.   JOURNAL OF NEUROSCIENCE

Molecular Mechanisms Contributing to TARP Regulation of Channel Conductance and Polyamine Block of Calcium-Permeable AMPA Receptors

(2014) D. Soto et al.   JOURNAL OF NEUROSCIENCE

Structural mechanism of glutamate receptor activation and desensitization

(2014) Joel R. Meyerson et al.   NATURE

Cornichon2 Dictates the Time Course of Excitatory Transmission at Individual Hippocampal Synapses

(2014) Sami Boudkkazi et al.   NEURON

Structure of an agonist-bound ionotropic glutamate receptor

(2014) M. V. Yelshanskaya et al.   SCIENCE

Cornichon Proteins Determine the Subunit Composition of Synaptic AMPA Receptors

(2013) Bruce E. Herring et al.   NEURON

Cornichons Control ER Export of AMPA Receptors to Regulate Synaptic Excitability

(2013) Penelope J. Brockie et al.   NEURON

Cornichons Modify Channel Properties of Recombinant and Glial AMPA Receptors

(2012) I. D. Coombs et al.   JOURNAL OF NEUROSCIENCE

High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes

(2012) Jochen Schwenk et al.   NEURON

Differences in AMPA and Kainate Receptor Interactomes Facilitate Identification of AMPA Receptor Auxiliary Subunit GSG1L

(2012) Natalie F. Shanks et al.   Cell Reports

Separation of Domain Contacts Is Required for Heterotetrameric Assembly of Functional NMDA Receptors

(2011) A. N. Farina et al.   JOURNAL OF NEUROSCIENCE

The Expanding Social Network of Ionotropic Glutamate Receptors: TARPs and Other Transmembrane Auxiliary Subunits

(2011) Alexander C. Jackson et al.   NEURON

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Contribution of the Global Subunit Structure and Stargazin on the Maturation of AMPA Receptors

(2010) N. F. Shanks et al.   JOURNAL OF NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating

(2010) Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors

(2009) J. Schwenk et al.   SCIENCE

Ionotropic Glutamate Receptors & CNS Disorders

(2008) Derek Bowie   CNS & Neurological Disorders-Drug Targets