Shear force sensing of epithelial Na+channel (ENaC) relies onN-glycosylated asparagines in the palm and knuckle domains of αENaC

Shear force modulates the activity of acid-sensing ion channels at low pH or in the presence of non-proton ligands

(2019) Daniel Barth et al.   Scientific Reports

Epithelial Na+ channel differentially contributes to shear stress-mediated vascular responsiveness in carotid and mesenteric arteries from mice

(2018) Zoe Ashley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Structure and mechanogating mechanism of the Piezo1 channel

(2018) Qiancheng Zhao et al.   NATURE

Structure of the human epithelial sodium channel by cryo-electron microscopy

(2018) Sigrid Noreng et al.   eLife

Mechanical Stimulation of Piezo1 Receptors Depends on Extracellular Matrix Proteins and Directionality of Force

(2017) Benjamin M. Gaub et al.   NANO LETTERS

Epithelial sodium channel (ENaC) family: Phylogeny, structure–function, tissue distribution, and associated inherited diseases

(2016) Israel Hanukoglu et al.   GENE

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Feeling Force: Physical and Physiological Principles Enabling Sensory Mechanotransduction

(2015) Samata Katta et al.   Annual Review of Cell and Developmental Biology

Mechanosensitive activation of CFTR by increased cell volume and hydrostatic pressure but not shear stress

(2015) Constanze Vitzthum et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mechanical systems biology of C. elegans touch sensation

(2015) Michael Krieg et al.   BIOESSAYS

Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel

(2015) Wei Zhang et al.   CELL

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

Epithelial Sodium Transport and Its Control by Aldosterone: The Story of Our Internal Environment Revisited

(2015) Bernard C. Rossier et al.   PHYSIOLOGICAL REVIEWS

Glycan:glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells

(2015) Christopher J. Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function

(2014) Deniz Baycin-Hizal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells

(2014) David G. Warnock et al.   Nature Reviews Nephrology

Unique Interweaved Microtubule Scaffold Mediates Osmosensory Transduction via Physical Interaction with TRPV1

(2014) Masha Prager-Khoutorsky et al.   NEURON

The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements

(2014) Jinfeng Teng et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mechanosensation: Tethered Ion Channels

(2013) Damiano Zanini et al.   CURRENT BIOLOGY

Laminar shear stress modulates the activity of heterologously expressed P2X4 receptors

(2011) Sarah Kessler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Intravenous Gene Therapy With PIM-1 Via a Cardiotropic Viral Vector Halts the Progression of Diabetic Cardiomyopathy Through Promotion of Prosurvival Signaling

(2011) Rajesh Katare et al.   CIRCULATION RESEARCH

Ménage à trois: Aldosterone, sodium and nitric oxide in vascular endothelium

(2010) Johannes Fels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Evidence for a protein tether involved in somatic touch

(2010) Jing Hu et al.   EMBO JOURNAL

Endothelial Epithelial Sodium Channel Inhibition Activates Endothelial Nitric Oxide Synthase via Phosphoinositide 3-Kinase/Akt in Small-Diameter Mesenteric Arteries

(2009) Francisco R. Pérez et al.   HYPERTENSION

Functional ENaC Channels Expressed in Endothelial Cells: a New Candidate for Mediating Shear Force

(2009) Su Wang et al.   MICROCIRCULATION

Pore architecture and ion sites in acid-sensing ion channels and P2X receptors

(2009) Eric B. Gonzales et al.   NATURE

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

Epithelial Na+ channels derived from human lung are activated by shear force

(2009) Martin Fronius et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Sensing Tension

(2008) Heather A. Drummond et al.   HYPERTENSION

Neurosensory mechanotransduction

(2008) Martin Chalfie   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine