Article
Biochemistry & Molecular Biology
Simona Saparova, Leos Ondris, Maria Koval'akova, Ol'ga Fricova, Hamed Peidayesh, Anton Baran, Maria Hutnikova, Ivan Chodak
Summary: Thermoplastic starch-based nanocomposites with varying glycerol content and montmorillonite as a nanofiller were studied during one-year storage using DMA, XRD, and NMR. The results showed the presence of starch-rich and glycerol-rich domains in the samples, with a decrease in the content of the amorphous phase and changes in molecular mobility during storage. Ordered structures were formed during storage, with higher glycerol content leading to larger content of ordered structures.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Zhilang Xu, Lun Yuan, Qisong Liu, Defu Li, Changdao Mu, Lei Zhao, Xinying Li, Liming Ge
Summary: In this study, dialdehyde starch-based nanoparticles were developed as a new strategy to crosslink collagen, aiming to improve its physicochemical properties. Compared to traditional dialdehyde starch crosslinked hydrogels, the dialdehyde starch nanoparticles crosslinked collagen hydrogels showed better physicochemical properties and potential application prospects in tissue engineering scaffolds.
CARBOHYDRATE POLYMERS
(2022)
Article
Agriculture, Multidisciplinary
Honghua Cao, Yonghao Liu, Ling Zhi, Shutong Jing, Zhengshengao Li, Dongfeng Wang, Ying Xu, Xun Sun
Summary: This study investigated the inhibitory effect of pre-gelatinized dialdehyde starch (P-DAS) on the deterioration of sea cucumber during high-temperature sterilization. The results showed that pre-gelatinization reduced the crystallinity and average molecular weight of dialdehyde starch (DAS), improved solubility, and unified particle sizes. The crosslinking power of P-DAS was higher than that of DAS, as evidenced by various texture profiles and analytical results. These findings have important implications for the development of new protein food stabilizing agents.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Polymer Science
Irene Derungs, Maite Rico, Joaquin Lopez, Luis Barral, Belen Montero, Rebeca Bouza
Summary: Thermoplastic starch (TPS) is a promising candidate for biodegradable polymers due to its wide availability, low cost, and biodegradability. The addition of montmorillonite nanofillers can improve the mechanical properties and thermal stability of TPS, with the most hydrophilic nanoclay, Cloisite Na+, being the most effective reinforcement.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2021)
Article
Biochemistry & Molecular Biology
Sylwia Grabska-Zielinska, Alina Sionkowska, Ewa Olewnik-Kruszkowska, Katarzyna Reczynska, Elzbieta Pamula
Summary: This study aimed to compare the physicochemical properties of three-dimensional scaffolds based on silk fibroin, collagen, and chitosan, cross-linked with dialdehyde starch (DAS) and dialdehyde chitosan (DAC). The results showed that DAS and DAC have different impacts on the properties of biopolymeric scaffolds, with DAS-crosslinked scaffolds exhibiting higher swelling ability, lower density, and lower mechanical properties compared to DAC-crosslinked scaffolds. Despite this, both types of scaffolds showed potential for use in regenerative medicine and tissue engineering, particularly in bone tissue engineering for healing small bone defects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Applied
Hamed Peidayesh, Abolfazl Heydari, Katarina Mosnackova, Ivan Chodak
Summary: This study focused on enhancing the stability of thermoplastic starch (TPS) through a dual crosslinking strategy, resulting in improved mechanical and chemical properties. The dually crosslinked TPS showed significant increases in tensile strength, Young's modulus, insoluble portion, and stability in water compared to conventional TPS. Rheology results indicated the formation of 3D networks and limited chain mobility in melted TPS induced by epichlorohydrin (ECH), leading to an extended relaxation process.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Natalia Smidova, Hamed Peidayesh, Anton Baran, Ol'ga Fricova, Maria Koval'akova, Ruzena Kralikova, Ivan Chodak
Summary: The mechanical properties and molecular mobility of thermoplastic starch and TPS-montmorillonite nanocomposite stored at different relative humidities were studied using mechanical testing, dynamic mechanical thermal analysis, and solid-state NMR spectroscopy. The addition of montmorillonite particles increased the tensile strength and Young's modulus, while decreasing the elongation at break. Higher humidity resulted in increased mobility of starch chain segments and a decrease in glass transition temperature, indicating the plasticizing effect of absorbed water molecules. Recrystallization was observed in the samples through NMR spectra analysis.
Article
Food Science & Technology
Qing Liu, Lin Gao, Yang Qin, Na Ji, Lei Dai, Liu Xiong, Qingjie Sun
Summary: The hydrophobicity of corn starch films was improved by adding a new type of covalently formed, oxidized debranched starch/chitosan nanoparticles (SC-NPs). SC-NPs were obtained by a Schiff-base crosslinking reaction between the aldehyde group of dialdehyde debranched starch and the amino group of chitosan. The films reinforced with 3% SC-NPs showed greater water contact angles and improved barrier properties compared to pure starch films.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Food Science & Technology
Yi Yuan, Qingrong Xue, Qiyong Guo, Guoyu Wang, Shixing Yan, Yongtai Wu, Lin Li, Xia Zhang, Bing Li
Summary: The introduction of tannic acid and heat treatment enhanced the properties of gelatin films, including UV blocking, thermal stability, and reduced water vapor permeability. The synergistic effect of tannic acid and enhanced covalent crosslinking improved the antioxidant capacity and inhibitory effect on S. aureus of the gelatin films.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Chemistry, Applied
Dagmara Bajer, Aleksandra Burkowska-But
Summary: This study evaluated the application of biodegradable films modified with ascorbic acid or caffeine and dialdehyde starch in the food packaging industry. The results showed that dialdehyde starch had cross-linking and hydrophobic effects on starch-based films. The addition of vitamin C promoted crystalline structure formation and improved hydrophilicity and antioxidant activity. Caffeine addition increased film hydrophobicity but reduced crystalline order in starch.
Article
Polymer Science
Anayansi Estrada-Monje, Sergio Alonso-Romero, Roberto Zitzumbo-Guzman, Ivan Alziri Estrada-Moreno, Erasto Armando Zaragoza-Contreras
Summary: The research found partial compatibility of cassava starch and corn starch with polycaprolactone (PCL) in the blends, along with changes in crystal quality of PCL and displacement of absorption bands in the infrared spectrum. The crystallinity of PCL in the presence of cassava and corn starch was higher than that of pure PCL, suggesting improved nucleation at the interface. Based on these findings, the blends are suitable for manufacturing short-term use products using conventional thermoplastic processing methods.
Article
Materials Science, Composites
Di Sheng Lai, Azlin Fazlina Osman, Sinar Arzuria Adnan, Ismail Ibrahim, Midhat Nabil Ahmad Salimi, Mariatti Jaafar Mustapha
Summary: This study introduced a hybrid nanofiller (1 wt% nanocellulose and 4 wt% nano bentonite) to enhance the mechanical strength and flexibility of thermoplastic starch (TPS) films. By crosslinking the TPS with the hybrid nanofiller and citric acid or tartaric acid, a high strength and fully biodegradable film was produced.
JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS
(2023)
Article
Food Science & Technology
Yue Peng, Minghao Wang, Xianhui Huang, Fuming Yang, Yongge Shi, Changbao Liao, Dianyu Yu
Summary: In this study, the sn-1,3-specific lipase from Rhizomucor miehei was immobilized with dialdehyde starch as a support activating agent and nano-sized Fe3O4 as a magnetic carrier to produce a structured triacylglycerol as a substitute for human milk fat enriched with OPO. The immobilized lipase showed a high load and a good recovery rate, and the relative enzyme activity was maintained even after being exposed to methanol. The synthesized OPO had a high content of palmitic acid at the sn-2 position and showed potential for use in infant formulas.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Polymer Science
Magdalena Zdanowicz, Kamila Salasinska
Summary: The aim of this study was to prepare and characterize composite materials based on thermoplastic starch (TPS)/deep eutectic solvent (DES). Potato starch was plasticized with ternary DES: urea:glycerol:sorbitol and modified with the selected fillers: microcrystalline cellulose and sodium montmorillonite. The results showed that the ternary DES effectively plasticized the polysaccharide leading to a highly amorphous structure of the TPS, and the introduction of fillers resulted in higher tensile strength and better barrier properties of the composite TPS films.
Article
Agriculture, Multidisciplinary
Huimin Yong, Huixia Hu, Zhihao Wang, Dawei Yun, Juan Kan, Jun Liu
Summary: By using acid-mediated coupling method, catechins were successfully conjugated onto dialdehyde starch to form stable dialdehyde starch-catechin conjugates. The conjugates exhibited improved thermal stability and enhanced stability of catechins in buffered solution. Furthermore, the conjugates showed higher antioxidant activity.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Pharmacology & Pharmacy
Narges Ajalli, Mehrab Pourmadadi, Fatemeh Yazdian, Majid Abdouss, Hamid Rashedi, Abbas Rahdar
Summary: For the first time, a nano-wound dressing was designed to optimize wound healing. The synthesized nanocomposite showed excellent mechanical properties, biodegradability, antimicrobial activity, and non-toxicity. The scratch test and animal model results demonstrated that this nanocomposite accelerated wound healing, achieving a 92.25% wound healing rate after 14 days. Therefore, it has the potential to replace traditional methods for wound healing.
CURRENT DRUG DELIVERY
(2023)
Article
Medicine, Research & Experimental
Shadi Sadat Nasiri, Zahed Ahmadi, Faramarz Afshar-Taromi
Summary: The aim of this research is to develop a bio-elastomer for tissue engineering applications using Poly(glycerol-sebacate)co-Poly(hydroxybutyrate) (PGS-co-PHB) with different amounts of bioglass 45S5 (BG) nanoparticles. The composite films were characterized and evaluated for their properties such as biodegradability, biocompatibility, hydrophilicity, antibacterial activity, and bioactivity. The results showed that the addition of BG nanoparticles improved the hydrophilicity of the composite films and enhanced their antibacterial and bioactive properties. These antibacterial composite films also showed excellent support for cell growth and proliferation, making them promising candidates for tissue engineering applications.
Article
Biochemistry & Molecular Biology
Amin Foroozandeh, Majid Abdouss, Hossein SalarAmoli, Mehrab Pourmadadi, Fatemeh Yazdian
Summary: Early detection is crucial in controlling and treating deadly ovarian cancer among women. Nanobiosensors are being used as a time-saving tool with high selectivity and sensitivity for biomarker detection. This study developed an electrochemical aptasensor using graphitic carbon nitrides, magnetic nanoparticles, and polyaniline to detect ovarian cancer antigen 125 (CA125) biomarkers. The aptasensor showed excellent selectivity, stability, and a broad dynamic linear range for evaluating patients' and healthy individuals' serum.
PROCESS BIOCHEMISTRY
(2023)
Article
Chemistry, Applied
Hamidreza Khodaeian, Zahed Ahmadi, Faramarz Afshar Taromi
Summary: This study investigates the effect of introducing poly(bisphenol-A borate) (PBAB) into benzoxazine coating on curing kinetics and thermal stability. The presence of PBAB catalyzes the curing reaction of benzoxazine coating. The curing kinetics were analyzed using differential scanning calorimetry (DSC) and the kinetic parameters of this system were determined using the Kissinger, Ozawa, and Borchardt-Daniels methods. Thermogravimetric analysis (TGA) results showed that increasing the percentage of PBAB significantly improved the thermal stability and char yield of the composite.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Engineering, Chemical
Mohamadreza Shakiba, Majid Abdouss, Saeedeh Mazinani, Mohammad Reza Kalaee
Summary: In this study, PANI was successfully functionalized onto electrospun PAN nanofibers through electrostatic interaction and hydrogen bonding, followed by ultrasound-assisted polymerization. The resulting APAN/PANI-S nanofibrous membrane demonstrated outstanding physical stability and high water flux in oil/water separation.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Agricultural Engineering
Mehrab Pourmadadi, Sepehr Darvishan, Majid Abdouss, Fatemeh Yazdian, Abbas Rahdar, Ana M. Diez-Pascual
Summary: A pH-sensitive nanocomposite was synthesized by coating halloysite nanotubes (HNT) with polyacrylic acid (PAA)/carboxymethyl cellulose (CMC) hydrogel for controlled delivery of curcumin (CUR) to MCF-7 cancer cells. Hazelnut oil and Span 80 surfactant were added to minimize the nanocomposite size and increase its uniformity, and to enhance the stability and retention of CUR as an anticancer drug, respectively. The resulting drug delivery system exhibited high drug loading and encapsulation efficiency, pH-sensitivity, and sustained drug release. It also demonstrated strong toxicity against MCF-7 cancer cells and induced apoptosis. These results highlight the potential of PAA/CMC/HNT/CUR hydrogel nanocomposites as smart drug delivery vehicles for breast cancer treatment.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Shadi Sadat Nasiri, Zahed Ahmadi, Faramarz Afshar-Taromi
Summary: This study developed a new nanocomposite scaffold of biopolymers for wound healing applications in tissue engineering, with the addition of antibacterial agents curcumin and bioglass nanoparticles. Properties such as morphology, physicomechanical properties, contact angles, antibacterial efficacy, and in vitro studies were explored. The results showed that the addition of bioglass nanoparticles significantly improved the hydrophilicity and water vapor transmission rate of the scaffolds, and the curcumin and bioglass effectively inhibited bacterial growth and promoted wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mehrab Pourmadadi, Alireza Tajiki, Majid Abdouss
Summary: A biocompatible and pH-responsive carrier nanoplatform was developed for targeted delivery of curcumin to breast cancer cells. The nanocomposite structure was confirmed and its particle size was found to be suitable for specific entry into cancer cells and minimal damage to healthy cells. In vitro tests showed that the PAA-Starch-TiO2 carrying Cur exhibited increased bioavailability and controlled release, leading to more effective cancer cell death through apoptosis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Hamidreza Abdouss, Mehrab Pourmadadi, Payam Zahedi, Majid Abdouss, Fatemeh Yazdian, Abbas Rahdar, Ana M. Diez-Pascual
Summary: A novel pH-sensitive nanocarrier was designed using chitosan, polyacrylic acid, and graphitic carbon nitride via water/oil/water emulsification for curcumin drug delivery. The incorporation of g-C3N4 into CS/PAA hydrogel was achieved, providing a high drug loading capacity and pH-sensitive release profile. The nanocarrier showed excellent efficacy in eliminating cancer cells and has great potential for controlled drug release.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mohammad Hossein Karami, Mehrab Pourmadadi, Majid Abdouss, Mohammad Reza Kalaee, Omid Moradi, Abbas Rahdar, Ana M. Diez-Pascual
Summary: This study successfully prepared a hydrogel nanocarrier containing chitosan, alumina, and carbon quantum dots for drug delivery of curcumin. The nanocarrier exhibited good stability and drug release profile, and showed anti-tumor activity against breast cancer cells. This finding is significant for tumor treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mehrab Pourmadadi, Ali Aslani, Majid Abdouss
Summary: The field of nanotechnology has opened up new possibilities for drug delivery systems, reducing the side effects of conventional chemotherapy. ZIF-8, a promising porous material, tends to aggregate in water, limiting its usefulness. By incorporating ZIF-8 into hydrogels made of gelatin and carboxymethylcellulose, we improved their mechanical strength and stability without aggregation. We used double emulsions with the hydrogels and biological macromolecules to create drug carriers with precise control over drug release. Characterization techniques confirmed the stability of the nanocarriers, which showed cytotoxicity against cancer cells and potential for further investigation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Composites
Mohammad Shadabfar, Morteza Ehsani, Hossein Ali Khonakdar, Majid Abdouss
Summary: This study successfully prepared a novel conducting polymer nanocomposite by chemically modifying carbon nanotubes and using carboxymethyl cellulose. The results showed improved dispersion and electrochemical properties for the nanocomposite containing oxidized carbon nanotubes.
POLYMER COMPOSITES
(2023)
Article
Polymer Science
Neda Rostami, Farzaneh Faridghiasi, Aida Ghebleh, Hadi Noei, Meisam Samadzadeh, Mohammad Mahmoudi Gomari, Alireza Tajiki, Majid Abdouss, Alireza Aminoroaya, Manisha Kumari, Reza Heidari, Vladimir N. Uversky, Bryan R. Smith
Summary: In this study, copolymers PLA-PEG-PLA and PEG-PLA-PEG were synthesized and compared for their delivery capacity of curcumin to MCF-7 breast cancer cells. The results showed that PLA-PEG-PLA had stronger interaction with the cell membrane and lower free energy, making it a better carrier for cell membrane penetration.
Article
Engineering, Environmental
Nafiseh Aghababaei, Majid Abdouss, Hassan Hosseini-Monfared, Farshid Ghanbari
Summary: A novel direct double Z-scheme O-g-C3N4/ZnO/TiO2@halloysite nanotubes (HNTs) photocatalyst was successfully synthesized to degrade and mineralize diclofenac (DCF) using a simple and low-cost method. Under specific conditions, the O-g-C3N4/ZnO/TiO2@HNTs degraded DCF completely, showing 1.66 and 2.4 times higher efficiency compared to other photocatalysts. Additionally, the photocatalyst also exhibited a significant removal rate of DCF from urban wastewater along with the removal of total organic carbon (TOC).
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Mohamadreza Shakiba, Parisa Jahangiri, Erfan Rahmani, Seyede Mahtab Hosseini, Ashkan Bigham, Amin Foroozandeh, Alireza Tajiki, Mehrab Pourmadadi, Shadi Nasiri, Shirzad Jouybar, Majid Abdouss
Summary: A PA6/PVA/CMWCNT-Cur hybrid nanofibrous composite with good antibacterial properties, mechanical properties, and controlled drug release function was successfully prepared for wound healing applications. The sample with a 0.75 wt % CMWCNT-Cur content was chosen as the most suitable sample due to its uniform nanofiber structure and excellent antibacterial features.
ACS APPLIED POLYMER MATERIALS
(2023)
