Article
Polymer Science
Yu Zhou, Yu-Ting Huang, Wei-Lin Xie, Shuangquan Liao, Ming-Chao Luo
Summary: The study constructs a covalent multiphase network through thermodynamic incompatibility-driven covalent network, increasing the strength and toughness of the material and providing a new strategy for the design of robust materials.
Review
Biochemistry & Molecular Biology
Francisco A. Catano, Viviana Moreno-Serna, Alejandro Cament, Carlos Loyo, Mauricio Yanez-S, J. Andres Ortiz, Paula A. Zapata
Summary: Starch is a sustainable biopolymer that can replace petrochemical-based plastics, but it needs to be processed and treated to become thermoplastic starch. By adding microcellulose or nanocellulose to thermoplastic starch through melt mixing, large-scale production can be achieved. This review compiles studies on the effect of plasticizers and different cellulosic fillers on the properties of thermoplastic starch obtained by melt mixing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Nanoscience & Nanotechnology
Ruosen Xie, Yu-Chung Chen, Yi Zhao, Nisakorn Yodsanit, Yuyuan Wang, Naoaki Yamamoto, Dai Yamanouchi, Shaoqin Gong
Summary: The injectable hydrogel reported in this study undergoes in situ covalent crosslinking to form a dual-crosslinking network (DCN) hydrogel, which provides a safe, consistent, and controlled embolization. It is mechanically stable, visible under X-ray imaging, and capable of achieving immediate embolization with long-term occlusion in vivo tests. The DCN hydrogel offers a viable, biocompatible, and cost-effective alternative to current embolic materials for endovascular embolization.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Piyawanee Jariyasakoolroj, Raksit Supthanyakul, Apirat Laobuthee, Amornrat Lertworasirikul, Rangrong Yoksan, Suttinun Phongtamrug, Suwabun Chirachanchai
Summary: The study successfully demonstrated the formation of covalent bonds between PLA and mTPS phases using 2D-NMR, leading to improved degradation rate and flexibility of the PLA film.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Environmental Sciences
Parveen Kumar Deralia, Amit Kumar Sonker, Anja Lund, Anette Larsson, Anna Strom, Gunnar Westman
Summary: This study describes a one-step and two-step strategy for the fabrication of flexible and stretchable thermoplastics using two structurally different arabinoxylans. The research findings suggest that the ratio of arabinose to xylose and hydrophobization significantly affect the melt processing and properties of the final material.
Article
Polymer Science
Muhammad Ghozali, Yenny Meliana, Mochamad Chalid
Summary: Thermoplastic starch (TPS) has disadvantages of poor mechanical properties, low thermal stability, and water sensitivity. This study aims to improve TPS properties through starch modification and the addition of benzoyl peroxide. The modified TPS showed improved density, tensile strength, and viscosity with the addition of benzoyl peroxide. However, it also resulted in decreased elongation at break, melt flow rate, and glass transition temperature.
Article
Nanoscience & Nanotechnology
Xiaoyang Bi, Mengjia Xu, Zhengchao Xie, Yan Li, Jiyu Tian, Zhenmin Wang, Zuankai Wang
Summary: Metal-thermoplastic hybrid structures have shown effectiveness in achieving lightweight design in aircraft components. However, the differences in physical and chemical properties between metal and thermoplastic pose challenges in fabricating high-reliability hybrid structures. A study discovers that covalent bonding at metal/thermoplastic interfaces plays a crucial role in the interfacial reliability of these structures. By grafting carboxyl functional group on polyetheretherketone (PEEK), the density and strength of interfacial covalency is increased, leading to the fabrication of high-reliability hybrid structures between PEEK and A6061-T6 aluminum alloy.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Applied
Santiago Estevez-Areco, Carlos Macchi, Lucas Guz, Silvia Goyanes, Alberto Somoza
Summary: The effect of citric acid (CA) concentration and water content on the free hole volume of thermoplastic cassava starch films (TPS) was studied. The increase in CA concentration leads to wider free hole volume distributions with lower mean values. The water vapour permeability was significantly higher in films incorporating 5 % (w/w) of CA, in line with the more open network of this material that was revealed in the hole volumes distribution.
CARBOHYDRATE POLYMERS
(2023)
Article
Polymer Science
Qinghua Song, Weiping Liu, Jiping Chen, Dacheng Zhao, Cheng Yi, Ruili Liu, Yi Geng, Yang Yang, Yizhu Zheng, Yuhui Yuan
Summary: This paper discusses the important defect of void content in automated fiber placement (AFP) manufacturing of large thermoplastic composites. By establishing a two-dimensional fluid extrusion flow model and using a cyclic iteration method, the changes in void content percentage were predicted. Experimental results confirmed the accuracy of the model, showing that laying speed and roller pressure have a significant impact on void content percentage.
Article
Materials Science, Multidisciplinary
Sung Kyu Kim, Hyun Wook Jung, Dasom Son, Jae Hyeok Han, DongHo Kang, Sang In Kang, Junhyuk Lee, Jin Kie Shim
Summary: In this study, a thermoplastic starch/poly(butylene adipate-co-terephthalate) (TPS/PBAT) blend with improved compatibility, mechanical properties, and water resistance was successfully prepared using in situ reactive compatibilization. The addition of 3% copolymer showed the best results, increasing the tensile strength of the blend and reducing the size of TPS domains in the PBAT matrix. The complex viscosity, storage modulus, and loss modulus also increased with increasing copolymer content, indicating enhanced compatibility between TPS and PBAT. Furthermore, the water resistance improved, as evidenced by increased contact angle and water vapor barrier properties.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Daniel Kodura, Hannes A. Houck, Fabian R. Bloesser, Anja S. Goldmann, Filip E. Du Prez, Hendrik Frisch, Christopher Barner-Kowollik
Summary: A controlled formation of 3D macromolecular architectures based on light-fueled covalent non-equilibrium chemistry was reported, showing the reversible folding of single polymer chains triggered by light. The stability of the folded SCNP indicates an inherent feature of the confined macromolecular environment.
Article
Polymer Science
Shulong Zeng, Li Li, Qi Wang
Summary: Polyvinyl alcohol (PVA) was modified by partially replacing glycerin with polyglycerol (PGL), resulting in improved thermal stability. PGL was found to have a strong hydrogen-bonding interaction with PVA, making it suitable as a plasticizer. The addition of PGL increased the volatilization temperature, shortened the crystallization time, improved tensile strength, and decreased melt index of PVA. Dynamic oscillatory rheological measurement showed that the lowest complex viscosity was achieved with 10 wt% PGL. This study demonstrates the potential of using PGL as a new plasticizer for PVA with high efficiency and thermal stability.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Review
Chemistry, Multidisciplinary
Ashanul Haque, Khalaf M. Alenezi, Muhammad S. Khan, Wai-Yeung Wong, Paul R. Raithby
Summary: The design and development of functional materials with practical applications require high standards. Understanding and controlling inter- and intra-molecular interactions offer opportunities for designing new materials. Manipulating the molecular structure can significantly alter these interactions and enhance the properties and functions of the material. Non-covalent interactions (NCIs) have been found to have beneficial effects, indicating that manipulating NCIs can generate functional materials with various physical properties for applications in catalysis, drug delivery, crystal engineering, etc. This review aims to explore the implications of NCIs on molecular packing, optical properties, and applications of functional pi-conjugated materials. Additionally, it attempts to delineate the effects of weak interactions on opto-electronic (O-E) applications.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Applied
Wenguang Wei, Min Wu, Weike Ren, Haoze Yu, Dongyu Sun
Summary: Due to the low degree of crosslinking, the application of citric acid crosslinking modification is restricted. In this study, a novel ion-esterification cooperative crosslinking-extrusion combined (CCEC) modification approach was proposed to improve the strength and tunable gel characteristics of citric acid-crosslinked starch. The results showed that the CCEC-modified starch had a significantly higher elastic modulus and a denser porous structure. By changing the cation concentration, the rheological characteristics of the gel could be efficiently controlled.
CARBOHYDRATE POLYMERS
(2024)
Article
Polymer Science
Mhd. Mazen Altayan, Tammam Al Darouich, Francois Karabet
Summary: This study investigated the rheological, structural, thermal, and mechanical properties of thermoplastic starches prepared from wheat and corn starches, finding that the differences in properties were mainly attributed to the varying amylose content in the starches. The study also revealed that wheat starch had a higher ability to form strong hydrogen bonds with plasticizers compared to corn starch, which was confirmed by FT-IR analysis. Additionally, a direct relationship between mechanical properties and amylose content was observed.
Article
Chemistry, Physical
Natalia Smidova, Hamed Peidayesh, Anton Baran, Ol'ga Fricova, Maria Koval'akova, Ruzena Kralikova, Ivan Chodak
Summary: The mechanical properties and molecular mobility of thermoplastic starch and TPS-montmorillonite nanocomposite stored at different relative humidities were studied using mechanical testing, dynamic mechanical thermal analysis, and solid-state NMR spectroscopy. The addition of montmorillonite particles increased the tensile strength and Young's modulus, while decreasing the elongation at break. Higher humidity resulted in increased mobility of starch chain segments and a decrease in glass transition temperature, indicating the plasticizing effect of absorbed water molecules. Recrystallization was observed in the samples through NMR spectra analysis.
Article
Polymer Science
Parvaneh Gheysoori, Azin Paydayesh, Maryam Jafari, Hamed Peidayesh
Summary: This study focuses on the development of thermoresponsive nanocomposite hydrogels for minimally invasive drug delivery. Gelatin-based hydrogels with poly (N-isopropylacrylamide) (PNIPAM) were prepared using response surface methodology. The PNIPAM nanoparticles showed successful polymerization and a reversible sol-gel transition close to body temperature. These nanocomposite hydrogels demonstrated antibacterial activity and good potential for targeted drug delivery.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Multidisciplinary Sciences
Samahe Sadjadi, Neda Abedian-Dehaghani, Abolfazl Heydari, Majid M. Heravi
Summary: A novel bi-functional catalytic composite using cyclodextrin and chitosan was designed, incorporating metal-organic framework encapsulated phosphomolybdic acid in a dual chitosan-cyclodextrin nanosponge bead. The composite demonstrated high catalytic activity in alcohol oxidation and cascade alcohol oxidation-Knoevenagel condensation reaction, with good yields and the ability to be recycled multiple times. The synergy between the components, amino groups acting as catalysts and cyclodextrin nanosponge as a phase transfer agent, contributed to the superior performance of the catalyst.
SCIENTIFIC REPORTS
(2023)
Review
Biochemistry & Molecular Biology
Roya Mohammadipour-Nodoushan, Shahla Shekarriz, Zahra Shariatinia, Abolfazl Heydari, Majid Montazer
Summary: Zinc oxide nanoparticles (ZnO NPs) have been widely studied and applied in the textile industry due to their potential in enhancing fabric properties. This review provides a comprehensive overview of the synthesis and various applications of ZnO-based nanomaterials, including UV protection, antimicrobial properties, electromagnetic shielding, and energy harvesting capabilities. The potential of ZnO-based nanomaterials in environmental cleaning and the development of nanocomposites is also discussed. The findings emphasize the importance of continued research to further advance the use of ZnO-based nanomaterials in the textile industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Abolfazl Heydari, Milad KhajeHassani, Haniyeh Daneshafruz, Sepideh Hamedi, Faeze Dorchei, Mario Kotlar, Fahimeh Kazeminava, Samahe Sadjadi, Farideh Doostan, Ivan Chodak, Hassan Sheibani
Summary: This study developed a nanocomposite material consisting of thermoplastic starch (TPS) reinforced with bentonite clay (BC) and encapsulated with vitamin B2 (VB). The study investigated the effects of VB on the physicochemical properties of TPS/BC films, including mechanical and thermal properties, water uptake, and weight loss in water. The addition of VB significantly increased the tensile strength and Young's modulus of TPS/BC films, with the highest values observed for nanocomposites containing 5 php of VB and 3 php of BC. The release of VB was controlled by the BC content, with higher BC content leading to lower VB release. These findings demonstrate the potential of TPS/BC/VB nanocomposites as environmentally friendly materials with improved mechanical properties and controlled release of VB, which can have significant applications in the biopolymer industry.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Parinaz Nezhad-Mokhtari, Fahimeh Kazeminava, Bahman Abdollahi, Pourya Gholizadeh, Abolfazl Heydari, Faranak Elmi, Mahmoud Abbaszadeh, Hossein Samadi Kafil
Summary: Recently, researchers have developed antibacterial wound dressings based on biomaterials that have shown good biocompatibility and the potential to accelerate wound healing. In this study, eco-friendly and biodegradable nanofibers were prepared by incorporating zeolite imidazolate framework nanoparticles and chamomile essential oil into a chitosan/ poly (& epsilon;-caprolactone) matrix using the electrospinning technique. The fabricated nanofibers demonstrated excellent cytocompatibility, proliferation, and antibacterial activity against common wound pathogens.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Roya Mohammadipour Nodoushan, Shahla Shekarriz, Zahra Shariatinia, Majid Montazer, Abolfazl Heydari
Summary: This study investigates the use of carbonized Zn-based metal-organic frameworks (Zn-MOF-5) under N2 and air to modify zinc oxide (ZnO) nanoparticles for the production of greyish-black cotton fabrics with enhanced photo and bio-active properties. The MOF-derived ZnO under N2 shows a significantly higher surface area than ZnO and MOF-derived ZnO under air. Various characterization techniques were used to analyze the products, and the treated fabrics were tested for tensile strength, dye degradation, antibacterial activity, and cytotoxicity. The findings suggest that the carbonized Zn-MOF under N2 is human-cell compatible, exhibits high antibacterial activity, and maintains stability against washing, displaying its potential for developing functional textiles.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Pharmacology & Pharmacy
Sima Beigoli, Zahra Sabouri, Samaneh Sadat Tabrizi Hafez Moghaddas, Abolfazl Heydari, Majid Darroudi
Summary: The application of nanotechnology in restorative and preventive dentistry has the potential to significantly improve the treatment of tooth structure diseases. This study focuses on the production and characteristics of a nanocomposite using amorphous calcium phosphate (ACP) and casein phosphopeptides (CPPs), which are widely used in oral care products. The nanocomposite shows antibacterial activity and low cytotoxicity, making it a potential candidate for healthcare products.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Environmental
Stavros X. Drakopoulos, Zdenko Spitalsky, Hamed Peidayesh, Laszlo Lendvai
Summary: Carbohydrate polymers are environmentally friendly materials due to their biodegradability and abundance. However, their molecular characteristics and hydrophilicity complicate spectroscopic investigation. In this study, thermoplastic starch with glycerol as a plasticizer was prepared using melt processing. The presence of water molecules was found to affect dielectric response and charge transport dynamics. Multiple dielectric processes and segmental relaxation processes were observed, and the ionic conductivity was found to be enhanced by the presence of water.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Polymer Science
Samahe Sadjadi, Abolfazl Heydari
Summary: In this study, a novel composite material was developed by combining β-cyclodextrin nanosponge and sodium alginate to immobilize palladium nanoparticles. The composite beads demonstrated excellent encapsulation capabilities and stability, making them suitable for hydrophobic substrates. The incorporation of cyclodextrin nanosponge within alginate beads improved the performance of the catalyst, allowing selective reduction of the nitro group in substrates with competing functionalities.
Review
Chemistry, Multidisciplinary
Siamak Javanbakht, Sima Darvishi, Faeze Dorchei, Maryam Hosseini-Ghalehno, Marjan Dehghani, Malihe Pooresmaeil, Yota Suzuki, Qurat Ul Ain, Leire Ruiz Rubio, Ahmad Shaabani, Takashi Hayashita, Hassan Namazi, Abolfazl Heydari
Summary: Diabetes mellitus is a prevalent chronic health condition, and monitoring blood glucose levels is crucial in diabetes management. However, developing noninvasive, rapid, accurate, sensitive, selective, and stable systems for continuous monitoring remains a challenge. Cyclodextrins can be instrumental in addressing these challenges and improving the performance and stability of glucose monitoring systems.
Article
Chemistry, Multidisciplinary
Zohreh Mehri Lighvan, Hossein Ali Khonakdar, Bahar Khodadadi, Azar Ramezanpour, Mina Rafie, Abolfazl Heydari, Yasir Waleed Abdulhameed, Sara Pirani, Ali Akbari
Summary: This study developed a stable and easy-recoverable nanoadsorbent (Fe3O4@CM-13-CDP@Tet-Cu(II)) for catalytic reduction of toxic dyes in wastewater. The material exhibited rich catalytic sites and hydrophobic properties, enabling efficient reduction processes. Various characterization techniques were employed to investigate the structure of the nanoadsorbent. The obtained material showed excellent catalytic ability, magnetic recoverability, and stability, making it a potential candidate for reducing multiple dyes in real wastewater samples.
RESULTS IN CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Samahe Sadjadi, Amir Masood Rezadoust, Soheila Yaghoubi, Eric Monflier, Abolfazl Heydari
Summary: In this study, a sustainable catalyst that operates effectively in aqueous environments was developed using cyclodextrin nanosponge as a scaffold and 3D printing technology. The resulting catalyst, which shows structural integrity and viability, demonstrated enhanced reusability in aqueous settings. Empirical evidence of the heterogeneous catalysis mode further supports the performance and potential of the catalyst for sustainable applications.
Article
Materials Science, Coatings & Films
Roya Mohammadipour Nodoushan, Shahla Shekarriz, Zahra Shariatinia, Majid Montazer, Abolfazl Heydari
Summary: This paper investigates the development of a multifunctional carbonized zinc (Zn)-based metal organic framework (MOF) coating on cotton fabric, revealing its synergistic effects of superhydrophobicity, oil-water separation, self-cleaning, and UV protecting properties. The coated fabric demonstrated significant superhydrophobic effects, efficient oil-water separation, and outstanding resistance to photo-corrosion, making it suitable for various applications including self-cleaning, UV protection, and water-oil separation.
SURFACE & COATINGS TECHNOLOGY
(2023)
Review
Polymer Science
Jan Kovac, Petra Priscakova, Helena Gbelcova, Abolfazl Heydari, Stanislav Ziaran
Summary: Injectable bioadhesive hydrogels show great potential in various biomedical applications, particularly in stem cell-based therapies for cartilage damage. This review examines the relationship between bioadhesion and stem cell differentiation, summarizes the principles of bioadhesion, discusses recent trends in bioadhesive hydrogels and their specific applications in cartilage repair.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
