A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a

BioBitsTM Health: Classroom activities exploring engineering, biology, and human health with fluorescent readouts

(2019) Jessica C. Stark et al.   ACS Synthetic Biology

Switching the activity of Cas12a using guide RNA strand displacement circuits

(2019) Lukas Oesinghaus et al.   Nature Communications

Perspective: Solidifying the impact of cell-free synthetic biology through lyophilization

(2018) Keith Pardee   BIOCHEMICAL ENGINEERING JOURNAL

A compact, low-cost, quantitative and multiplexed fluorescence detection platform for point-of-care applications

(2018) Uwadiae Obahiagbon et al.   BIOSENSORS & BIOELECTRONICS

Field-deployable viral diagnostics using CRISPR-Cas13

(2018) Cameron Myhrvold et al.   SCIENCE

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

CRISPR-Cas12a-assisted nucleic acid detection

(2018) Shi-Yuan Li et al.   Cell Discovery

RNA Binding and HEPN-Nuclease Activation Are Decoupled in CRISPR-Cas13a

(2018) Akshay Tambe et al.   Cell Reports

BioBits™ Bright: A fluorescent synthetic biology education kit

(2018) Jessica C. Stark et al.   Science Advances

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes

(2017) Alexandra East-Seletsky et al.   MOLECULAR CELL

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components

(2016) Keith Pardee et al.   CELL

Advances in addressing technical challenges of point-of-care diagnostics in resource-limited settings

(2016) ShuQi Wang et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

iSpinach: a fluorogenic RNA aptamer optimized forin vitroapplications

(2016) Alexis Autour et al.   NUCLEIC ACIDS RESEARCH

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

Emerging Technologies for Next-Generation Point-of-Care Testing

(2015) Sandeep Kumar Vashist et al.   TRENDS IN BIOTECHNOLOGY

Toehold Switches: De-Novo-Designed Regulators of Gene Expression

(2014) Alexander A. Green et al.   CELL

Paper-Based Synthetic Gene Networks

(2014) Keith Pardee et al.   CELL

Paper-based microfluidic point-of-care diagnostic devices

(2013) Ali Kemal Yetisen et al.   LAB ON A CHIP

An economical fluorescence detector for lab-on-a-chip devices with a light emitting photodiode and a low-cost avalanche photodiode

(2011) Jing Wu et al.   ANALYST

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices

(2009) Andres W. Martinez et al.   ANALYTICAL CHEMISTRY

A low-cost light-emitting diode induced fluorescence detector for capillary electrophoresis based on an orthogonal optical arrangement

(2009) Feng-Bo Yang et al.   TALANTA

High-sensitivity, disposable lab-on-a-chip with thin-film organic electronics for fluorescence detection

(2008) Andrea Pais et al.   LAB ON A CHIP