Diosmetin exhibits anti‐proliferative and anti‐inflammatory effects on TNF‐α‐stimulated human rheumatoid arthritis fibroblast‐like synoviocytes through regulating the Akt and NF‐κB signaling pathways

Melatonin attenuates TNF-α and IL-1β expression in synovial fibroblasts and diminishes cartilage degradation: implications for the treatment of rheumatoid arthritis

(2019) Chien-Chung Huang et al.   JOURNAL OF PINEAL RESEARCH

Diosmetin Suppresses Neuronal Apoptosis and Inflammation by Modulating the Phosphoinositide 3-Kinase (PI3K)/AKT/Nuclear Factor-κB (NF-κB) Signaling Pathway in a Rat Model of Pneumococcal Meningitis

(2019) Yan Zhang et al.   MEDICAL SCIENCE MONITOR

miR‐124a inhibits the proliferation and inflammation in rheumatoid arthritis fibroblast‐like synoviocytes via targeting PIK3/NF‐κB pathway

(2019) BiLing Yang et al.   CELL BIOCHEMISTRY AND FUNCTION

Kaempferitrin inhibits proliferation, induces apoptosis, and ameliorates inflammation in human rheumatoid arthritis fibroblast‐like synoviocytes

(2019) Jing Wang et al.   PHYTOTHERAPY RESEARCH

Diosmetin Alleviates Lipopolysaccharide-Induced Acute Lung Injury through Activating the Nrf2 Pathway and Inhibiting the NLRP3 Inflammasome

(2018) Qinmei Liu et al.   Biomolecules & Therapeutics

Inhibition of NF-κB signaling pathway induces apoptosis and suppresses proliferation and angiogenesis of human fibroblast-like synovial cells in rheumatoid arthritis

(2018) Zhong-Bin Xia et al.   MEDICINE

Betulinic acid inhibits cell proliferation, migration, and inflammatory response in rheumatoid arthritis fibroblast‐like synoviocytes

(2018) Jing Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Diosmetin inhibits osteoclast formation and differentiation and prevents LPS-induced osteolysis in mice

(2018) Siyuan Shao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice

(2018) Yingsong Jiang et al.   MEDICAL SCIENCE MONITOR

Anti-inflammatory effects of pitavastatin in interleukin-1β-induced SW982 human synovial cells

(2017) Bin-Feng Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pathogenetic insights from the treatment of rheumatoid arthritis

(2017) Iain B McInnes et al.   LANCET

Cellular and molecular perspectives in rheumatoid arthritis

(2017) Douglas J. Veale et al.   Seminars in Immunopathology

Diosmetin inhibits the metastasis of hepatocellular carcinoma cells by downregulating the expression levels of MMP-2 and MMP-9

(2016) JIE LIU et al.   Molecular Medicine Reports

Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-κB pathway in HepG2 cells

(2016) Jie Qiao et al.   Oncology Letters

Diosmetin inhibits the expression of alpha-hemolysin in Staphylococcus aureus

(2015) Shui Liu et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Cyr61 participates in the pathogenesis of rheumatoid arthritis by promoting proIL-1β production by fibroblast-like synoviocytes through an AKT-dependent NF-κB signaling pathway

(2015) Xianjin Zhu et al.   CLINICAL IMMUNOLOGY

Synovial fibroblasts integrate inflammatory and neuroendocrine stimuli to drive rheumatoid arthritis

(2015) Torsten Lowin et al.   Expert Review of Clinical Immunology

Selective modulation of MAPKs contribute to the anti-proliferative and anti-inflammatory activities of 1,7-dihydroxy-3,4-dimethoxyxanthone in rheumatoid arthritis-derived fibroblast-like synoviocyte MH7A cells

(2015) Jian Zuo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor ΚB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells

(2014) Jinchao Li et al.   Drug Design Development and Therapy

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

(2012) E. Choy   RHEUMATOLOGY

Effects of plant-derived polyphenols on TNF-α and nitric oxide production induced by advanced glycation endproducts

(2010) Dave Chandler et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Diosmetin Induces Human Osteoblastic Differentiation Through the Protein Kinase C/p38 and Extracellular Signal-Regulated Kinase 1/2 Pathway

(2008) Ya-Ling Hsu et al.   JOURNAL OF BONE AND MINERAL RESEARCH