Therapeutic sildenafil inhibits pulmonary damage induced by cigarette smoke exposure and bacterial inhalation in rats

Restoring Th17/Treg balance via modulation of STAT3 and STAT5 activation contributes to the amelioration of chronic obstructive pulmonary disease by Bufei Yishen formula

(2018) Peng Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Sildenafil in severe pulmonary hypertension associated with chronic obstructive pulmonary disease: A randomized controlled multicenter clinical trial

(2017) Patrizio Vitulo et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Sildenafil in a cigarette smoke-induced model of COPD in the guinea-pig

(2015) David Domínguez-Fandos et al.   EUROPEAN RESPIRATORY JOURNAL

Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice

(2015) Michael Seimetz et al.   PLoS One

Stimulation of Soluble Guanylate Cyclase Prevents Cigarette Smoke–induced Pulmonary Hypertension and Emphysema

(2014) Norbert Weissmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Novel Mechanisms of Sildenafil in Pulmonary Hypertension Involving Cytokines/Chemokines, MAP Kinases and Akt

(2014) Tamas Kiss et al.   PLoS One

Nitric Oxide Deficiency and Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2013) James R. Klinger et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sildenafil to improve respiratory rehabilitation outcomes in COPD: a controlled trial

(2013) Isabel Blanco et al.   EUROPEAN RESPIRATORY JOURNAL

A Rat Model for Stable Chronic Obstructive Pulmonary Disease Induced by Cigarette Smoke Inhalation and Repetitive Bacterial Infection

(2012) Ya Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Sildenafil for Chronic Obstructive Pulmonary Disease: A Randomized Crossover Trial

(2012) David J. Lederer et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

(2011) Michael Seimetz et al.   CELL

The three R’s of lung health and disease: repair, remodeling, and regeneration

(2011) Michael F. Beers et al.   JOURNAL OF CLINICAL INVESTIGATION

Hemodynamic and Gas Exchange Effects of Sildenafil in Patients with Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension

(2009) Isabel Blanco et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sildenafil therapy in secondary pulmonary hypertension: Is there benefit in prolonged use?

(2009) T.H. Chapman et al.   VASCULAR PHARMACOLOGY

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension

(2008) R. T. Schermuly et al.   EUROPEAN RESPIRATORY JOURNAL