Stimulation of Soluble Guanylate Cyclase Prevents Cigarette Smoke–induced Pulmonary Hypertension and Emphysema

Pulmonary vascular abnormalities in chronic obstructive pulmonary disease undergoing lung transplant

(2013) Victor I. Peinado et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Riociguat for the Treatment of Pulmonary Arterial Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Structure and Regulation of Soluble Guanylate Cyclase

(2012) Emily R. Derbyshire et al.   Annual Review of Biochemistry

Riociguat for interstitial lung disease and pulmonary hypertension: a pilot trial

(2012) Marius M. Hoeper et al.   EUROPEAN RESPIRATORY JOURNAL

Reactive oxygen and nitrogen species in pulmonary hypertension

(2012) Diana M. Tabima et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Soluble Guanylate Cyclase Stimulator Riociguat Ameliorates Pulmonary Hypertension Induced by Hypoxia and SU5416 in Rats

(2012) Michaela Lang et al.   PLoS One

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

(2011) Michael Seimetz et al.   CELL

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

(2011) Johannes-Peter Stasch et al.   CIRCULATION

Effects of cigarette smoke and hypoxia on pulmonary circulation in the guinea pig

(2011) E. Ferrer et al.   EUROPEAN RESPIRATORY JOURNAL

Riociguat for the treatment of pulmonary hypertension

(2011) Ralph T Schermuly et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Statin Reverses Smoke-induced Pulmonary Hypertension and Prevents Emphysema but Not Airway Remodeling

(2010) Joanne L. Wright et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pulmonary Hypertension in COPD: Epidemiology, Significance, and Management

(2010) Omar A. Minai et al.   CHEST

Riociguat for chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension: a phase II study

(2010) H. A. Ghofrani et al.   EUROPEAN RESPIRATORY JOURNAL

Reduction of ICAM-1 expression by carbon monoxide via soluble guanylate cyclase activation accounts for modulation of neutrophil migration

(2010) Daniela Dal-Secco et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice

(2009) Norbert Weissmann et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The soluble guanylyl cyclase inhibitor NS-2028 reduces vascular endothelial growth factor-induced angiogenesis and permeability

(2009) Lucia Morbidelli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Tadalafil Therapy for Pulmonary Arterial Hypertension

(2009) Nazzareno Galiè et al.   CIRCULATION

Nitric Oxide–Independent Vasodilator Rescues Heme-Oxidized Soluble Guanylate Cyclase From Proteasomal Degradation

(2009) Sabine Meurer et al.   CIRCULATION RESEARCH

Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease

(2009) Joan Albert Barberà et al.   DRUGS

First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in pulmonary hypertension

(2009) F. Grimminger et al.   EUROPEAN RESPIRATORY JOURNAL

Antigrowth Properties of BAY 41-2272 in Vascular Smooth Muscle Cells

(2009) Natalia N Mendelev et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mechanisms of cigarette smoke-induced COPD: insights from animal models

(2008) Andrew Churg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pulmonary Vascular Involvement in COPD

(2008) Víctor I. Peinado et al.   CHEST

Pulmonary hypertension in COPD

(2008) A. Chaouat et al.   EUROPEAN RESPIRATORY JOURNAL

Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension

(2008) R. T. Schermuly et al.   EUROPEAN RESPIRATORY JOURNAL

Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation

(2008) A. A. Canalli et al.   HAEMATOLOGICA