HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist

Evaluation of cyclic luciferin as a substrate for luminescence measurements in in vitro and in vivo applications

(2019) Maxim Abakumov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive oxygen species induce epithelial‑mesenchymal transition, glycolytic switch, and mitochondrial repression through the Dlx‑2/Snail signaling pathways in MCF‑7 cells

(2019) Su Lee et al.   Molecular Medicine Reports

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response

(2018) Stefan Petkov et al.   PLoS One

Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

(2018) A. A. Latanova et al.   Scientific Reports

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

(2018) Rawan El-Amine et al.   Redox Biology

TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer

(2018) Li-Ting Wang et al.   ONCOGENE

HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell

(2018) Gabriel Valentín-Guillama et al.   Cancers

Activation of Polyamine Catabolism by N1,N11-Diethylnorspermine in Hepatic HepaRG Cells Induces Dedifferentiation and Mesenchymal-Like Phenotype

(2018) Olga N. Ivanova et al.   Cells

Evolving epidemiology of HIV-associated malignancies

(2017) Meredith S. Shiels et al.   Current Opinion in HIV and AIDS

HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness

(2017) Francesca Caccuri et al.   Infectious Agents and Cancer

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice

(2017) Anastasia Latanova et al.   Journal of Immunology Research

Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer

(2017) V. P. Baklaushev et al.   Scientific Reports

Pivotal role of AKAP121 in mitochondrial physiology

(2016) Alexander Czachor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Oxidative Stress during HIV Infection: Mechanisms and Consequences

(2016) Alexander V. Ivanov et al.   Oxidative Medicine and Cellular Longevity

ROS, Calcium, and Electric Signals: Key Mediators of Rapid Systemic Signaling in Plants

(2016) Simon Gilroy et al.   PLANT PHYSIOLOGY

Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice

(2016) Virginia A. Carroll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Entrance of the Tat protein of HIV-1 into human uterine cervical carcinoma cells causes upregulation of HPV-E6 expression and a decrease in p53 protein levels

(2016) Giovanni Barillari et al.   Oncology Letters

HuR silencing elicits oxidative stress and DNA damage and sensitizes human triple-negative breast cancer cells to radiotherapy

(2016) Meghna Mehta et al.   Oncotarget

Posttranslational control of HuR function

(2016) Ioannis Grammatikakis et al.   Wiley Interdisciplinary Reviews-RNA

HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation

(2016) Kieran A. Brune et al.   PLoS One

The RNA-binding protein HuR is essential for the B cell antibody response

(2015) Manuel D Diaz-Muñoz et al.   NATURE IMMUNOLOGY

Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis

(2015) Riccardo Dolcetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated map of HIV genome-wide variation from a population perspective

(2015) Guangdi Li et al.   Retrovirology

HCV Core Protein Uses Multiple Mechanisms to Induce Oxidative Stress in Human Hepatoma Huh7 Cells

(2015) Alexander Ivanov et al.   Viruses-Basel

Tumor cell secretion of soluble factor(s) for specific immunosuppression

(2015) Arihiro Kano   Scientific Reports

Impact of Maternal HIV Seroconversion during Pregnancy on Early Mother to Child Transmission of HIV (MTCT) Measured at 4-8 Weeks Postpartum in South Africa 2011-2012: A National Population-Based Evaluation

(2015) Thu-Ha Dinh et al.   PLoS One

A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses

(2014) Anna N. Kolomeets et al.   AIDS

HIV-1 Matrix Protein p17 Promotes Lymphangiogenesis and Activates the Endothelin-1/Endothelin B Receptor Axis

(2014) Francesca Caccuri et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Glutathione peroxidase 4 is reversibly induced by HCV to control lipid peroxidation and to increase virion infectivity

(2014) Charlène Brault et al.   GUT

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway

(2014) Min Xue et al.   NUCLEIC ACIDS RESEARCH

“Glowing Head” Mice: A Genetic Tool Enabling Reliable Preclinical Image-Based Evaluation of Cancers in Immunocompetent Allografts

(2014) Chi-Ping Day et al.   PLoS One

The Lysine 65 Residue in HIV-1 Reverse Transcriptase Function and in Nucleoside Analog Drug Resistance

(2014) Scott Garforth et al.   Viruses-Basel

The Spleen in Local and Systemic Regulation of Immunity

(2013) Vincenzo Bronte et al.   IMMUNITY

HIV Infection in Gastric Epithelial Cells

(2013) Rui Liu et al.   JOURNAL OF INFECTIOUS DISEASES

Postintegration HIV-1 Infection of Cervical Epithelial Cells Mediates Contact-Dependent Productive Infection of T Cells

(2013) Amanda M. Micsenyi et al.   JOURNAL OF INFECTIOUS DISEASES

Defining the Interaction of HIV-1 with the Mucosal Barriers of the Female Reproductive Tract

(2013) A. M. Carias et al.   JOURNAL OF VIROLOGY

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway

(2013) X Zhu et al.   ONCOGENE

Multilayer control of the EMT master regulators

(2013) H Zheng et al.   ONCOGENE

Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent

(2013) F M Davis et al.   ONCOGENE

Modulation of Oxidative Stress by Twist Oncoproteins

(2013) Nicolas Floc'h et al.   PLoS One

46. HIV-induced epithelial–mesenchymal transition in mucosal epithelium facilitates HPV paracellular penetration

(2013) Sharof M. Tugizov et al.   Sexual Health

Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme’s performance in gene immunization

(2013) Maria Isaguliants et al.   Human Vaccines & Immunotherapeutics

PG545, a Heparan Sulfate Mimetic, Reduces Heparanase Expression In Vivo, Blocks Spontaneous Metastases and Enhances Overall Survival in the 4T1 Breast Carcinoma Model

(2012) Edward Hammond et al.   PLoS One

Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance

(2012) Hong-Tao Xu et al.   Retrovirology

EMT and Oxidative Stress: A Bidirectional Interplay Affecting Tumor Malignancy

(2011) Elisa Giannoni et al.   ANTIOXIDANTS & REDOX SIGNALING

HIV Infection, Immunodeficiency, Viral Replication, and the Risk of Cancer

(2011) M. J. Silverberg et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells

(2011) Alexander V. Ivanov et al.   PLoS One

ROS signaling: the new wave?

(2011) Ron Mittler et al.   TRENDS IN PLANT SCIENCE

HIV-1 Efficient Entry in Inner Foreskin Is Mediated by Elevated CCL5/RANTES that Recruits T Cells and Fuels Conjugate Formation with Langerhans Cells

(2011) Zhicheng Zhou et al.   PLoS Pathogens

Reduced Fitness in Cell Culture of HIV-1 with Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Mutations Correlates with Relative Levels of Reverse Transcriptase Content and RNase H Activity in Virions

(2010) J. Wang et al.   JOURNAL OF VIROLOGY

Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans–T cell conjugates

(2010) Y Ganor et al.   Mucosal Immunology

TWISTing an embryonic transcription factor into an oncoprotein

(2010) S Ansieau et al.   ONCOGENE

Epidemiological Networks and Drug Resistance of HIV Type 1 in Krasnoyarsk Region, Russia

(2009) Olga A. Rumyantseva et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Twist expression promotes migration and invasion in hepatocellular carcinoma

(2009) Noriyuki Matsuo et al.   BMC CANCER

gp340 Promotes Transcytosis of Human Immunodeficiency Virus Type 1 in Genital Tract-Derived Cell Lines and Primary Endocervical Tissue

(2009) E. Stoddard et al.   JOURNAL OF VIROLOGY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription

(2009) Kylie Warren et al.   Viruses-Basel

Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy

(2008) Christophe Piketty et al.   AIDS

Genome-wide hepatitis C virus amino acid covariance networks can predict response to antiviral therapy in humans

(2008) Rajeev Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?

(2008) Giuseppe Nunnari et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse transcription in infected cells

(2008) Julie Lemay et al.   Retrovirology

Control of mitochondria dynamics and oxidative metabolism by cAMP, AKAPs and the proteasome

(2008) Annalisa Carlucci et al.   TRENDS IN CELL BIOLOGY

HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response

(2008) Elizaveta S. Starodubova et al.   VACCINE

HIV-1 reverse transcriptase inhibitor resistance mutations and fitness: A view from the clinic and ex vivo

(2008) Javier Martinez-Picado et al.   VIRUS RESEARCH