HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell

Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

(2017) Jr-M Yang et al.   ONCOGENE

HIV-1 Gp120 clade B/C induces a GRP78 driven cytoprotective mechanism in astrocytoma

(2017) Sheila N. López et al.   Oncotarget

NKCC1 Regulates Migration Ability of Glioblastoma Cells by Modulation of Actin Dynamics and Interacting with Cofilin

(2017) Paula Schiapparelli et al.   EBioMedicine

Phosphatidylcholine-specific phospholipase C inhibition down- regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells

(2017) Laura Mercurio et al.   PLoS One

IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury

(2017) Victoria E. Thaney et al.   Scientific Reports

Isolation of an HIV-1 neutralizing peptide mimicking the CXCR4 and CCR5 surface from the heavy-chain complementary determining region 3 repertoire of a viremic controller

(2016) Andy Chevigne et al.   AIDS

Suppression of HIV-1 Infectivity by Human Glioma Cells

(2016) Sheikh Ariful Hoque et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Survival and Proliferation of Neural Progenitor–Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism

(2016) Anda-Alexandra Calinescu et al.   CLINICAL CANCER RESEARCH

Astrocytes as an HIV Reservoir: Mechanism of HIV Infection

(2016) Guan-Han Li et al.   CURRENT HIV RESEARCH

CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study

(2016) Viveka Nand Yadav et al.   Oncotarget

CCL5 activation of CCR5 regulates cell metabolism to enhance proliferation of breast cancer cells

(2016) Darrin Gao et al.   Open Biology

HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection

(2016) Christian Ostalecki et al.   EBioMedicine

Cumulative Incidence of Cancer Among Persons With HIV in North America

(2015) Michael J. Silverberg et al.   ANNALS OF INTERNAL MEDICINE

CXCR4 and Glioblastoma

(2015) Peter J. Richardson   Anti-Cancer Agents in Medicinal Chemistry

Proline metabolism and cancer

(2015) James M. Phang et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

(2015) Mohamed Hassanein et al.   INTERNATIONAL JOURNAL OF CANCER

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development

(2015) Qian Wang et al.   JOURNAL OF PATHOLOGY

HCP-01DIAGNOSIS AND MANAGEMENT OF HIGH-GRADE GLIOMA IN PATIENTS WITH HIV

(2015) Nattasha Acevedo et al.   NEURO-ONCOLOGY

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer

(2015) M van Geldermalsen et al.   ONCOGENE

Proline biosynthesis augments tumor cell growth and aerobic glycolysis: involvement of pyridine nucleotides

(2015) Wei Liu et al.   Scientific Reports

Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway

(2015) Kimberleve Rolón-Reyes et al.   PLoS One

Targeting glutamine transport to suppress melanoma cell growth

(2014) Qian Wang et al.   INTERNATIONAL JOURNAL OF CANCER

CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120

(2014) Ricky Maung et al.   JOURNAL OF IMMUNOLOGY

HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells

(2014) Andrea Hegedus et al.   Retrovirology

Serine and glycine metabolism in cancer

(2014) Ivano Amelio et al.   TRENDS IN BIOCHEMICAL SCIENCES

CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment

(2014) Roberto Würth et al.   Frontiers in Cellular Neuroscience

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

(2013) L. Willems et al.   BLOOD

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

(2013) F. Baenke et al.   Disease Models & Mechanisms

Past, present and future: 30 years of HIV research

(2013) Françoise Barré-Sinoussi et al.   NATURE REVIEWS MICROBIOLOGY

HIV: Cell Binding and Entry

(2013) C. B. Wilen et al.   Cold Spring Harbor Perspectives in Medicine

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

SLC1A5 Mediates Glutamine Transport Required for Lung Cancer Cell Growth and Survival

(2012) M. Hassanein et al.   CLINICAL CANCER RESEARCH

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

Metabolic switching and fuel choice during T-cell differentiation and memory development

(2012) Gerritje J. W. Windt et al.   IMMUNOLOGICAL REVIEWS

The Chemokine CCL5 Regulates Glucose Uptake and AMP Kinase Signaling in Activated T Cells to Facilitate Chemotaxis

(2012) Olivia Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCL5, CCR1 and CCR5 in murine glioblastoma: Immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5

(2012) Kien Pham et al.   JOURNAL OF NEUROIMMUNOLOGY

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

(2012) Barbara Chaneton et al.   NATURE

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

(2012) Dimitrios Anastasiou et al.   Nature Chemical Biology

CCL5 and CCR5 Interaction Promotes Cell Motility in Human Osteosarcoma

(2012) Shih-Wei Wang et al.   PLoS One

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

(2012) W. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation

(2012) Tomas Garzon-Muvdi et al.   PLOS BIOLOGY

Chemokines in health and disease

(2011) Dayanidhi Raman et al.   EXPERIMENTAL CELL RESEARCH

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Why tumours eat tryptophan

(2011) George C. Prendergast   NATURE

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Detection of HIV gp120 in Plasma During Early HIV Infection Is Associated with Increased Proinflammatory and Immunoregulatory Cytokines

(2010) Jenna Rychert et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols

(2010) Katja Dettmer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Spectrum of Cancer Risk Late After AIDS Onset in the United States

(2010) Edgar P. Simard   ARCHIVES OF INTERNAL MEDICINE

Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter

(2010) Seiji Miyauchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

(2010) Sirkku Pollari et al.   BREAST CANCER RESEARCH AND TREATMENT

Cumulative incidence of cancer among individuals with acquired immunodeficiency syndrome in the United States

(2010) Edgar P Simard et al.   CANCER

Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis

(2010) Jennifer F Barger et al.   ENDOCRINE-RELATED CANCER

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol

(2010) Juliana de Saldanha da Gama Fischer et al.   Journal of Proteomics

Potential Therapeutic Effect of Glycogen Synthase Kinase 3  Inhibition against Human Glioblastoma

(2009) K. Miyashita et al.   CLINICAL CANCER RESEARCH

Management of Glioblastoma Multiforme in HIV Patients: a Case Series and Review of Published Studies

(2009) J.R. Hall et al.   CLINICAL ONCOLOGY

IgE, allergy, and risk of glioma: Update from the San Francisco Bay Area Adult Glioma Study in the Temozolomide era

(2009) Joseph L. Wiemels et al.   INTERNATIONAL JOURNAL OF CANCER

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE

Mutations in PYCR1 cause cutis laxa with progeroid features

(2009) Bruno Reversade et al.   NATURE GENETICS

Activation of Wnt/β-catenin/Tcf signaling pathway in human astrocytomas

(2009) Gangadhara Reddy Sareddy et al.   NEUROCHEMISTRY INTERNATIONAL

The brain-specific factor FEZ1 is a determinant of neuronal susceptibility to HIV-1 infection

(2009) J. Haedicke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

(2009) T. Hitosugi et al.   Science Signaling

CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

(2008) Chun-Yin Huang et al.   BIOCHEMICAL PHARMACOLOGY

Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein

(2008) Nobukazu Shimada et al.   GENES TO CELLS

Pyruvate kinase M2 is a phosphotyrosine-binding protein

(2008) Heather R. Christofk et al.   NATURE