HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway

Human Immunodeficiency Virus Type 1 Tat Accelerates Kaposi Sarcoma-Associated Herpesvirus Kaposin A-Mediated Tumorigenesis of Transformed Fibroblasts In Vitro as well as in Nude and Immunocompetent Mice

(2015) Xiuying Chen et al.   NEOPLASIA

Viral Cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition

(2014) Tiffany Jones et al.   CELL CYCLE

Inhibition of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication by HIV-1 Nef and Cellular MicroRNA hsa-miR-1258

(2014) Q. Yan et al.   JOURNAL OF VIROLOGY

HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors

(2014) Xun Liu et al.   Scientific Reports

Genomewide Mapping and Screening of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) 3' Untranslated Regions Identify Bicistronic and Polycistronic Viral Transcripts as Frequent Targets of KSHV MicroRNAs

(2013) Z. Bai et al.   JOURNAL OF VIROLOGY

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway

(2013) X Zhu et al.   ONCOGENE

HIV-1 Tat Promotes Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) vIL-6-Induced Angiogenesis and Tumorigenesis by Regulating PI3K/PTEN/AKT/GSK-3β Signaling Pathway

(2013) Feng Zhou et al.   PLoS One

Cellular MicroRNAs 498 and 320d Regulate Herpes Simplex Virus 1 Induction of Kaposi’s Sarcoma-Associated Herpesvirus Lytic Replication by Targeting RTA

(2013) Qin Yan et al.   PLoS One

Role of microRNAs in the immune system, inflammation and cancer

(2013) Jennifer Raisch   WORLD JOURNAL OF GASTROENTEROLOGY

KSHV MicroRNAs Mediate Cellular Transformation and Tumorigenesis by Redundantly Targeting Cell Growth and Survival Pathways

(2013) Rosalie Moody et al.   PLoS Pathogens

Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway

(2012) Y. Li et al.   BLOOD

In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2

(2012) Francesca Fornari et al.   JOURNAL OF PATHOLOGY

A Kaposi's Sarcoma-Associated Herpesvirus MicroRNA and Its Variants Target the Transforming Growth Factor   Pathway To Promote Cell Survival

(2012) X. Lei et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus MicroRNAs Target IRAK1 and MYD88, Two Components of the Toll-Like Receptor/Interleukin-1R Signaling Cascade, To Reduce Inflammatory-Cytokine Expression

(2012) J. R. Abend et al.   JOURNAL OF VIROLOGY

YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29

(2012) Karen Tumaneng et al.   NATURE CELL BIOLOGY

Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN–AKT pathway

(2012) T Palumbo et al.   ONCOGENE

Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection

(2012) Michael G. Schrauder et al.   PLoS One

A microRNA Encoded by Kaposi Sarcoma-Associated Herpesvirus Promotes B-Cell Expansion In Vivo

(2012) Christine Dahlke et al.   PLoS One

Control of cell proliferation pathways by microRNAs

(2011) María José Bueno et al.   CELL CYCLE

A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKɛ

(2011) Deguang Liang et al.   CELL RESEARCH

Viruses and microRNAs: RISCy interactions with serious consequences

(2011) B. R. Cullen   GENES & DEVELOPMENT

Nef Inhibits Glucose Uptake in Adipocytes and Contributes to Insulin Resistance in Human Immunodeficiency Virus Type I Infection

(2011) Laura Cheney et al.   JOURNAL OF INFECTIOUS DISEASES

Human Immunodeficiency Virus Type 1 Induces Lytic Cycle Replication of Kaposi's-Sarcoma-Associated Herpesvirus: Role of Ras/c-Raf/MEK1/2, PI3K/AKT, and NF-κB Signaling Pathways

(2011) Xiaolei Zhu et al.   JOURNAL OF MOLECULAR BIOLOGY

Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation

(2011) Jeong-Gu Kang et al.   JOURNAL OF PATHOLOGY

Kaposi's Sarcoma-Associated Herpesvirus-Encoded MicroRNA miR-K12-11 Attenuates Transforming Growth Factor Beta Signaling through Suppression of SMAD5

(2011) Y. Liu et al.   JOURNAL OF VIROLOGY

A Kaposi's Sarcoma-Associated Herpesvirus-Encoded Ortholog of MicroRNA miR-155 Induces Human Splenic B-Cell Expansion in NOD/LtSz-scid IL2R null Mice

(2011) I. W. Boss et al.   JOURNAL OF VIROLOGY

miR-K12-7-5p Encoded by Kaposi's Sarcoma-Associated Herpesvirus Stabilizes the Latent State by Targeting Viral ORF50/RTA

(2011) Xianzhi Lin et al.   PLoS One

Kaposi's Sarcoma Herpesvirus microRNAs Target Caspase 3 and Regulate Apoptosis

(2011) Guillaume Suffert et al.   PLoS Pathogens

HIV Type 1 Nef Is Released from Infected Cells in CD45+ Microvesicles and Is Present in the Plasma of HIV-Infected Individuals

(2010) A.D. Raymond et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle

(2010) Chih-Chung Lu et al.   EMBO REPORTS

KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming

(2010) A. Hansen et al.   GENES & DEVELOPMENT

Risk Factors Influencing Antibody Responses to Kaposiʼs Sarcoma-Associated Herpesvirus Latent and Lytic Antigens in Patients Under Antiretroviral Therapy

(2010) Moraima Guadalupe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Epigenetic Regulation of Kaposi's Sarcoma-Associated Herpesvirus Latency by Virus-Encoded MicroRNAs That Target Rta and the Cellular Rbl2-DNMT Pathway

(2010) F. Lu et al.   JOURNAL OF VIROLOGY

Regulation of Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Receptor Protein (TWEAKR) Expression by Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Prevents TWEAK-Induced Apoptosis and Inflammatory Cytokine Expression

(2010) J. R. Abend et al.   JOURNAL OF VIROLOGY

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

(2010) Xiufen Lei et al.   NATURE CELL BIOLOGY

miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator

(2010) Dimitrios Lagos et al.   NATURE CELL BIOLOGY

Upregulation of xCT by KSHV-Encoded microRNAs Facilitates KSHV Dissemination and Persistence in an Environment of Oxidative Stress

(2010) Zhiqiang Qin et al.   PLoS Pathogens

A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line

(2009) EVELYN ARANDA et al.   BIOLOGICAL RESEARCH

Kaposi sarcoma-associated herpesvirus (KSHV): Molecular biology and oncogenesis

(2009) Kwun Wah Wen et al.   CANCER LETTERS

Regulation of KSHV Lytic Switch Protein Expression by a Virus-Encoded MicroRNA: An Evolutionary Adaptation that Fine-Tunes Lytic Reactivation

(2009) Priya Bellare et al.   Cell Host & Microbe

Diverse Herpesvirus MicroRNAs Target the Stress-Induced Immune Ligand MICB to Escape Recognition by Natural Killer Cells

(2009) Daphna Nachmani et al.   Cell Host & Microbe

Emerging common themes in regulation of PIKKs and PI3Ks

(2009) Harri Lempiäinen et al.   EMBO JOURNAL

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

Pivotal Advance: Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded microRNA specifically induce IL-6 and IL-10 secretion by macrophages and monocytes

(2009) Zhiqiang Qin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mechanism of Fas Signaling Regulation by Human Herpesvirus 8 K1 Oncoprotein

(2009) Z. Berkova et al.   JNCI-Journal of the National Cancer Institute

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

Differential Expression of PTEN-Targeting MicroRNAs miR-19a and miR-21 in Cowden Syndrome

(2008) Marcus G. Pezzolesi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN

(2008) H. Yang et al.   CANCER RESEARCH

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

(2008) L. Du et al.   CLINICAL CANCER RESEARCH

Constitutive Activation of Phosphatidylinositol 3-Kinase Signaling Pathway Down-regulates TLR4-mediated Tumor Necrosis Factor-α Release in Alveolar Macrophages from Asymptomatic HIV-positive Personsin Vitro

(2008) Souvenir D. Tachado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells

(2008) V. A. Morris et al.   JOURNAL OF VIROLOGY

Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs

(2008) Joseph M Ziegelbauer et al.   NATURE GENETICS

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY