A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer’s Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3

Potentially beneficial effects of rhamnose on skin aging: an in vitro and in vivo study

(2019) H. Pageon et al.   INTERNATIONAL JOURNAL OF COSMETIC SCIENCE

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

(2019) Peisu Zhang et al.   NATURE NEUROSCIENCE

Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer’s Disease

(2019) P. Hemachandra Reddy et al.   Cells

Ketones improves Apolipoprotein E4-related memory deficiency via sirtuin 3

(2019) Junxiang Yin et al.   Aging-US

Honokiol Alleviates Cognitive Deficits of Alzheimer’s Disease (PS1V97L) Transgenic Mice by Activating Mitochondrial SIRT3

(2018) Haitao Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives

(2018) Darren J. Baker et al.   JOURNAL OF CLINICAL INVESTIGATION

SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway

(2018) Sindhu Ramesh et al.   PLoS One

The Association of Tau With Mitochondrial Dysfunction in Alzheimer's Disease

(2018) Ying Cheng et al.   Frontiers in Neuroscience

Ageing, Cellular Senescence and Neurodegenerative Disease

(2018) Marios Kritsilis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1

(2018) Bruno Alexandre Quadros Gomes et al.   Oxidative Medicine and Cellular Longevity

Polysaccharides from Ganoderma lucidum attenuate microglia-mediated neuroinflammation and modulate microglial phagocytosis and behavioural response

(2017) Qing Cai et al.   Journal of Neuroinflammation

Amyloid-β and Mitochondria in Aging and Alzheimer's Disease: Implications for Synaptic Damage and Cognitive Decline

(2017) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease

(2016) Aneesa Ansari et al.   AGING CELL

Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease

(2016) Xiao-Dong Pan et al.   CHINESE MEDICAL JOURNAL

PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

(2016) Juan Carlos Corona et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Regulatory Pathways in the Pathogenesis of Alzheimer’s Disease

(2016) Reginald C. Adiele et al.   JOURNAL OF ALZHEIMERS DISEASE

Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate

(2016) Ting Yang et al.   JOURNAL OF NEUROSCIENCE

Resveratrol and Alzheimer’s Disease: Mechanistic Insights

(2016) Touqeer Ahmed et al.   MOLECULAR NEUROBIOLOGY

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

(2016) Loukia Katsouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Dysfunction in Alzheimer’s Disease and the Rationale for Bioenergetics Based Therapies

(2016) Isaac G. Onyango et al.   Aging and Disease

The role of inflammation in age-related disease

(2016) T. Kevin Howcroft et al.   Aging-US

Mitochondrial Sirt3 Expression is Decreased in APP/PS1 Double Transgenic Mouse Model of Alzheimer’s Disease

(2015) Wenxiu Yang et al.   NEUROCHEMICAL RESEARCH

Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease

(2015) Fabian A. Cabezas-Opazo et al.   Oxidative Medicine and Cellular Longevity

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Astaxanthin diferulate as a bifunctional antioxidant

(2014) T. B. R. Papa et al.   FREE RADICAL RESEARCH

Smart Soup, a Traditional Chinese Medicine Formula, Ameliorates Amyloid Pathology and Related Cognitive Deficits

(2014) Yujun Hou et al.   PLoS One

Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and Carcinogenesis

(2013) Randa Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT3 Deacetylates ATP Synthase F1 Complex Proteins in Response to Nutrient- and Exercise-Induced Stress

(2013) Athanassios Vassilopoulos et al.   ANTIOXIDANTS & REDOX SIGNALING

Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration

(2013) Brad Kincaid et al.   Frontiers in Aging Neuroscience

Cellular and molecular mechanisms of mitochondrial function

(2012) Laura D. Osellame et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Synthesis and Antifungal Activities of Glycosylated Derivatives of the Cyclic Peptide Fungicide Caspofungin

(2012) Junxiang Guo et al.   ChemMedChem

Quantitative Acetylome Analysis Reveals the Roles of SIRT1 in Regulating Diverse Substrates and Cellular Pathways

(2012) Yue Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Diammonium Glycyrrhizinate Upregulates PGC-1α and Protects against Aβ1–42-Induced Neurotoxicity

(2012) Xiaolei Zhu et al.   PLoS One

Amyloid oligomers: formation and toxicity of Aβ oligomers

(2010) Masafumi Sakono et al.   FEBS Journal

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

PGC-1α Expression Decreases in the Alzheimer Disease Brain as a Function of Dementia

(2009) Weiping Qin et al.   ARCHIVES OF NEUROLOGY

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

(2009) Paula I. Moreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Expression of senescence-associated β-galactosidase (SA-β-Gal) by human skin fibroblasts, effect of advanced glycation end-products and fucose or rhamnose-rich polysaccharides

(2008) V. Ravelojaona et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

(2008) P. Hemachandra Reddy et al.   TRENDS IN MOLECULAR MEDICINE