RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice

Network-based integrated analysis of omics data reveal novel players of TGF-β1-induced EMT in human peritoneal mesothelial cells

(2019) Soo Min Han et al.   Scientific Reports

RASSF10 Is a TGFβ-Target That Regulates ASPP2 and E-Cadherin Expression and Acts as Tumor Suppressor That Is Epigenetically Downregulated in Advanced Cancer

(2019) Antje M. Richter et al.   Cancers

Epigenetic Biomarkers in Cancer

(2018) Yuen Yee Cheng et al.   DISEASE MARKERS

MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data

(2018) Vijayachitra Modhukur et al.   Epigenomics

Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets

(2018) Ádám Nagy et al.   Scientific Reports

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

(2018) Angelina V. Vaseva et al.   CANCER CELL

Colorectal cancer screening: An updated review of the available options

(2017) Iyad A Issa et al.   WORLD JOURNAL OF GASTROENTEROLOGY

ZAR1 is a novel epigenetically inactivated tumour suppressor in lung cancer

(2017) Antje M. Richter et al.   Clinical Epigenetics

Current and Prospective Protein Biomarkers of Lung Cancer

(2017) Tatiana Zamay et al.   Cancers

The dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanisms

(2016) Tanja Haag et al.   BMC CANCER

Formation of Renal Cysts and Tumors inVhl/Trp53-Deficient Mice Requires HIF1α and HIF2α

(2016) Désirée Schönenberger et al.   CANCER RESEARCH

Human Cancers Express a Mutator Phenotype: Hypothesis, Origin, and Consequences

(2016) Lawrence A. Loeb   CANCER RESEARCH

Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

(2016) A. Marcell Szász et al.   Oncotarget

Ras-association domain family 10 acts as a novel tumor suppressor through modulating MMP2 in hepatocarcinoma

(2016) W Liu et al.   Oncogenesis

Aberrant Promoter Methylation of the Tumour Suppressor RASSF10 and Its Growth Inhibitory Function in Breast Cancer

(2016) Antje Richter et al.   Cancers

The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease

(2015) Tamina Seeger-Nukpezah et al.   Nature Reviews Nephrology

Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway

(2015) X Li et al.   ONCOGENE

Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer

(2015) Anna Díez-Villanueva et al.   Epigenetics & Chromatin

Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics

(2015) Alan Kirwan et al.   Biomed Research International

Promoter Methylation Status of Ras-Association Domain Family Member in Pheochromocytoma

(2015) Antje M. Richter et al.   Frontiers in Endocrinology

RASSF tumor suppressor gene family: Biological functions and regulation

(2014) Natalia Volodko et al.   FEBS LETTERS

The evolution of thymic lymphomas in p53 knockout mice

(2014) Crissy Dudgeon et al.   GENES & DEVELOPMENT

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical Validation of an Epigenetic Assay to Predict Negative Histopathological Results in Repeat Prostate Biopsies

(2014) Alan W. Partin et al.   JOURNAL OF UROLOGY

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

(2014) Steffen Kiehl et al.   Scientific Reports

RASSF10 is epigenetically silenced and functions as a tumor suppressor in gastric cancer

(2013) Ziran Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RASSF10 is epigenetically inactivated and induces apoptosis in lung cancer cell lines

(2013) Yanfu Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Genetic background and tumour susceptibility in mouse models

(2013) J Puccini et al.   CELL DEATH AND DIFFERENTIATION

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas

(2013) M. Gostissa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-1/133a Clusters Cooperatively Specify the Cardiomyogenic Lineage by Adjustment of Myocardin Levels during Embryonic Heart Development

(2013) Katharina Wystub et al.   PLoS Genetics

Aberrant Promoter Hypermethylation of RASSF Family Members in Merkel Cell Carcinoma

(2013) Antje Richter et al.   Cancers

Clinical Utility of an Epigenetic Assay to Detect Occult Prostate Cancer in Histopathologically Negative Biopsies: Results of the MATLOC Study

(2012) Grant D. Stewart et al.   JOURNAL OF UROLOGY

Cancer biomarkers

(2012) N. Lynn Henry et al.   Molecular Oncology

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer

(2012) A M Richter et al.   Oncogenesis

RASSF10 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin but Uncommon in Nevus Cell Nevi

(2011) Peter Helmbold et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Frequent epigenetic inactivation of RASSF10 in thyroid cancer

(2010) Undraga Schagdarsurengin et al.   Epigenetics

Mast cell homeostasis and the JAK–STAT pathway

(2010) J K Morales et al.   GENES AND IMMUNITY

Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis

(2010) V K Hill et al.   ONCOGENE

The N-terminal RASSF family: a new group of Ras-association-domaincontaining proteins, with emerging links to cancer formation

(2009) Victoria Sherwood et al.   BIOCHEMICAL JOURNAL

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Megaoesophagus inRassf1a-null mice

(2009) Louise van der Weyden et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

(2009) Luke B Hesson et al.   Molecular Cancer

HCV Tumor Promoting Effect Is Dependent on Host Genetic Background

(2009) Naama Klopstock et al.   PLoS One

Genetic Background and the Dilemma of Translating Mouse Studies to Humans

(2008) Juan Rivera et al.   IMMUNITY