Structural basis of non-canonical transcriptional regulation by the σA-bound iron-sulfur protein WhiB1 in M. tuberculosis

Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding

(2019) Hande Boyaci et al.   NATURE

Spx, a versatile regulator of the Bacillus subtilis stress response

(2019) Heinrich Schäfer et al.   CURRENT GENETICS

Identification of novel Spx regulatory pathways in Bacillus subtilis uncovers a close relationship between the CtsR and Spx regulons

(2019) Daniel F. Rojas-Tapias et al.   JOURNAL OF BACTERIOLOGY

Fidaxomicin jams Mycobacterium tuberculosis RNA polymerase motions needed for initiation via RbpA contacts

(2018) Hande Boyaci et al.   eLife

Clustal Omega for making accurate alignments of many protein sequences

(2017) Fabian Sievers et al.   PROTEIN SCIENCE

Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding

(2017) Anne Volbeda et al.   Nature Communications

Structure of a Wbl protein and implications for NO sensing by M. tuberculosis

(2017) Bassam K. Kudhair et al.   Nature Communications

Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

(2017) Elizabeth A. Hubin et al.   Nature Communications

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA

(2017) Elizabeth A Hubin et al.   eLife

Reassessing the Structure and Function Relationship of the O2 Sensing Transcription Factor FNR

(2017) Erin L. Mettert et al.   ANTIOXIDANTS & REDOX SIGNALING

Genome-wide characterization of monomeric transcriptional regulators in Mycobacterium tuberculosis

(2016) Lipeng Feng et al.   MICROBIOLOGY-SGM

Charge-density analysis of an iron–sulfur protein at an ultra-high resolution of 0.48 Å

(2016) Yu Hirano et al.   NATURE

Local and global regulation of transcription initiation in bacteria

(2016) Douglas F. Browning et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis of transcription activation

(2016) Y. Feng et al.   SCIENCE

Efficient and simple generation of multiple unmarked gene deletions in Mycobacterium smegmatis

(2016) Xu-Jian Mao et al.   Scientific Reports

Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA

(2015) Elizabeth A. Hubin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The crystal structure of the global anaerobic transcriptional regulator FNR explains its extremely fine-tuned monomer-dimer equilibrium

(2015) A. Volbeda et al.   Science Advances

Iron–Sulfur Clusters as Biological Sensors: The Chemistry of Reactions with Molecular Oxygen and Nitric Oxide

(2014) Jason C. Crack et al.   ACCOUNTS OF CHEMICAL RESEARCH

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Post-Translational Regulation via Clp Protease Is Critical for Survival of Mycobacterium tuberculosis

(2014) Ravikiran M. Raju et al.   PLoS Pathogens

Mechanism of [4Fe-4S](Cys)4Cluster Nitrosylation Is Conserved among NO-responsive Regulators

(2013) Jason C. Crack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV)

(2013) Ján Burian et al.   NUCLEIC ACIDS RESEARCH

Activating Transcription in Bacteria

(2012) David J. Lee et al.   Annual Review of Microbiology

Transcription Activation by Escherichia coli Rob at Class II Promoters: Protein–Protein Interactions between Rob's N-Terminal Domain and the σ70 Subunit of RNA Polymerase

(2012) Lanyn P. Taliaferro et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure-Function Relationships of the Mycobacterium tuberculosis Transcription Factor WhiB1

(2012) Laura J. Smith et al.   PLoS One

Gene Expression of Mycobacterium tuberculosis Putative Transcription Factors whiB1-7 in Redox Environments

(2012) Christer Larsson et al.   PLoS One

Mycobacterium tuberculosis WhiB1 represses transcription of the essential chaperonin GroEL2

(2012) Melanie R. Stapleton et al.   TUBERCULOSIS

CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures

(2012) Eva Chovancova et al.   PLoS Computational Biology

Mycobacterium tuberculosis WhiB3: A Novel Iron–Sulfur Cluster Protein That Regulates Redox Homeostasis and Virulence

(2011) Vikram Saini et al.   ANTIOXIDANTS & REDOX SIGNALING

The Mycobacterial Transcriptional RegulatorwhiB7Gene Links Redox Homeostasis and Intrinsic Antibiotic Resistance

(2011) Ján Burian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mycobacterium tuberculosisWhiB1 is an essential DNA-binding protein with a nitric oxide-sensitive iron–sulfur cluster

(2010) Laura J. Smith et al.   BIOCHEMICAL JOURNAL

Protein–Protein Interactions Between σ70 Region 4 of RNA Polymerase and Escherichia coli SoxS, a Transcription Activator That Functions by the Prerecruitment Mechanism: Evidence for “Off-DNA” and “On-DNA” Interactions

(2010) M. Ammar Zafar et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanistic Insight into the Nitrosylation of the [4Fe−4S] Cluster of WhiB-like Proteins

(2010) Jason C. Crack et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improved mycobacterial tetracycline inducible vectors

(2010) Kerstin J. Williams et al.   PLASMID

NsrR targets in theEscherichia coligenome: new insights into DNA sequence requirements for binding and a role for NsrR in the regulation of motility

(2009) Jonathan D. Partridge et al.   MOLECULAR MICROBIOLOGY

Three-dimensional EM structure of an intact activator-dependent transcription initiation complex

(2009) B. P. Hudson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous Nitric Oxide Protects Bacteria Against a Wide Spectrum of Antibiotics

(2009) I. Gusarov et al.   SCIENCE