Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures

Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition

(2017) Wei Lin et al.   MOLECULAR CELL

Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA

(2017) Elizabeth A Hubin et al.   eLife

Massively Systematic Transcript End Readout, “MASTER”: Transcription Start Site Selection, Transcriptional Slippage, and Transcript Yields

(2015) Irina O. Vvedenskaya et al.   MOLECULAR CELL

Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble

(2015) Yuhong Zuo et al.   MOLECULAR CELL

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

(2015) Jayan Rammohan et al.   NUCLEIC ACIDS RESEARCH

Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA

(2015) Elizabeth A. Hubin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm : Figure 1.

(2015) Sumit Chakraborty et al.   Cold Spring Harbor Perspectives in Medicine

Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD

(2014) Elizabeth Davis et al.   NUCLEIC ACIDS RESEARCH

X-ray Crystal Structure ofEscherichia coliRNA Polymerase σ70Holoenzyme

(2013) Katsuhiko S. Murakami   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of E. coli RNA Polymerase Regulation by ppGpp Is Suggested by the Structure of their Complex

(2013) Yuhong Zuo et al.   MOLECULAR CELL

Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of  70 domain 1.1

(2013) B. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

(2013) Teresa Cortes et al.   Cell Reports

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Structural Basis of Transcription Initiation

(2012) Y. Zhang et al.   SCIENCE

Comparative Analysis of Regulatory Elements between Escherichia coli and Klebsiella pneumoniae by Genome-Wide Transcription Start Site Profiling

(2012) Donghyuk Kim et al.   PLoS Genetics

Structural Basis for Promoter −10 Element Recognition by the Bacterial RNA Polymerase σ Subunit

(2011) Andrey Feklistov et al.   CELL

Mechanism of Bacterial Transcription Initiation: RNA Polymerase - Promoter Binding, Isomerization to Initiation-Competent Open Complexes, and Initiation of RNA Synthesis

(2011) Ruth M. Saecker et al.   JOURNAL OF MOLECULAR BIOLOGY

A novel method for the production ofin vivo-assembled, recombinantEscherichia coliRNA polymerase lacking the α C-terminal domain

(2011) Kelly-Anne Twist et al.   PROTEIN SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach

(2010) Natacha Opalka et al.   PLOS BIOLOGY

CarD Is an Essential Regulator of rRNA Transcription Required for Mycobacterium tuberculosis Persistence

(2009) Christina L. Stallings et al.   CELL

Molecular Evolution of Multisubunit RNA Polymerases: Sequence Analysis

(2009) William J. Lane et al.   JOURNAL OF MOLECULAR BIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

A Full-Length Group 1 Bacterial Sigma Factor Adopts a Compact Structure Incompatible with DNA Binding

(2008) Edmund C. Schwartz et al.   CHEMISTRY & BIOLOGY