The structure and oxidation of the eye lens chaperone αA-crystallin

Local unfolding of the HSP27 monomer regulates chaperone activity

(2019) T. Reid Alderson et al.   Nature Communications

An integrated workflow for crosslinking mass spectrometry

(2019) Marta L Mendes et al.   Molecular Systems Biology

A quantitative map of glutathione in the aging human lens

(2017) Angus C. Grey et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Structural Basis for the Interaction of a Human Small Heat Shock Protein with the 14-3-3 Universal Signaling Regulator

(2017) Nikolai N. Sluchanko et al.   STRUCTURE

Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked byIn VitroOxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens

(2015) Xingjun Fan et al.   MOLECULAR & CELLULAR PROTEOMICS

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client

(2015) Andi Mainz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

EMDataBank unified data resource for 3DEM

(2015) Catherine L. Lawson et al.   NUCLEIC ACIDS RESEARCH

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client

(2015) Andi Mainz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distance restraints from crosslinking mass spectrometry: Mining a molecular dynamics simulation database to evaluate lysine-lysine distances

(2014) Eric D. Merkley et al.   PROTEIN SCIENCE

Targeted conformational search with map-restrained self-guided Langevin dynamics: Application to flexible fitting into electron microscopic density maps

(2013) Xiongwu Wu et al.   JOURNAL OF STRUCTURAL BIOLOGY

sHSP in the eye lens: Crystallin mutations, cataract and proteostasis

(2012) Alice R. Clark et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

αA-Crystallin and αB-Crystallin Reside in Separate Subcellular Compartments in the Developing Ocular Lens

(2012) Rajendra K. Gangalum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using Hydrogen/Deuterium Exchange Mass Spectrometry to Study Conformational Changes in Granulocyte Colony Stimulating Factor upon PEGylation

(2012) Hui Wei et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Quaternary Dynamics of αB-Crystallin as a Direct Consequence of Localised Tertiary Fluctuations in the C-Terminus

(2011) Andrew J. Baldwin et al.   JOURNAL OF MOLECULAR BIOLOGY

Computer controlled cryo-electron microscopy – TOM2 a software package for high-throughput applications

(2011) Andreas Korinek et al.   JOURNAL OF STRUCTURAL BIOLOGY

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

(2011) S. Jehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple molecular architectures of the eye lens chaperone  B-crystallin elucidated by a triple hybrid approach

(2011) N. Braun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A quantitative NMR spectroscopic examination of the flexibility of the C-terminal extensions of the molecular chaperones, αA- and αB-crystallin

(2010) Teresa M. Treweek et al.   EXPERIMENTAL EYE RESEARCH

Regions Outside the α-Crystallin Domain of the Small Heat Shock Protein Hsp26 Are Required for Its Dimerization

(2010) Jin Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

(2010) Stefan Jehle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Non-3D domain swapped crystal structure of truncated zebrafish alphaA crystallin

(2010) A. Laganowsky et al.   PROTEIN SCIENCE

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

(2010) Arthur Laganowsky et al.   PROTEIN SCIENCE

Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes

(2009) G. Marius Clore et al.   CHEMICAL REVIEWS

The eye lens chaperone  -crystallin forms defined globular assemblies

(2009) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic analysis of the oxidation of cysteine residues in human age-related nuclear cataract lenses

(2008) Peter G. Hains et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Genetics of crystallins: Cataract and beyond

(2008) Jochen Graw   EXPERIMENTAL EYE RESEARCH

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY