Visualization of AMPA receptors in living human brain with positron emission tomography

Hyperexcitability of the local cortical circuit in mouse models of tuberous sclerosis complex

(2019) Jian-Ping Zhao et al.   Molecular Brain

Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8

(2019) Beatriz Herguedas et al.   SCIENCE

Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM

(2019) Yan Zhao et al.   SCIENCE

Lower synaptic density is associated with depression severity and network alterations

(2019) Sophie E. Holmes et al.   Nature Communications

CRMP2-binding compound, edonerpic maleate, accelerates motor function recovery from brain damage

(2018) Hiroki Abe et al.   SCIENCE

Multi-Target Approach for Drug Discovery against Schizophrenia

(2018) Magda Kondej et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The AMPA Receptor Code of Synaptic Plasticity

(2018) Graham H. Diering et al.   NEURON

A human PET study of [11C]HMS011, a potential radioligand for AMPA receptors

(2017) Keisuke Takahata et al.   EJNMMI Research

Radiosynthesis and preliminary PET evaluation of 18 F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors

(2016) Gengyang Yuan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

Optical inactivation of synaptic AMPA receptors erases fear memory

(2016) Kiwamu Takemoto et al.   NATURE BIOTECHNOLOGY

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors

(2016) Kazumi Koga et al.   EJNMMI Research

Development of Novel PET Probes for Central 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid Receptors

(2015) Norihito Oi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Virtually Instantaneous, Room-Temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes

(2015) Hong Geun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors in epilepsy

(2014) Rita Citraro et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

AMPA receptors as drug targets in neurological disease - advantages, caveats, and future outlook

(2012) Philip K.-Y. Chang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Randomized phase III study 306: Adjunctive perampanel for refractory partial-onset seizures

(2012) G. L. Krauss et al.   NEUROLOGY

Acute knockdown of AMPA receptors reveals a trans-synaptic signal for presynaptic maturation

(2011) Tara E Tracy et al.   EMBO JOURNAL

Serotonin Mediates Cross-Modal Reorganization of Cortical Circuits

(2011) Susumu Jitsuki et al.   NEURON

Developing a complete pharmacology for AMPA receptors: A perspective on subtype-selective ligands

(2010) James J. Fleming et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Challenges for and current status of research into positive modulators of AMPA receptors

(2010) Simon E Ward et al.   BRITISH JOURNAL OF PHARMACOLOGY

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON