Training the trainable cells of the immune system and beyond

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host’s Response to Pathogens

(2019) Mihai G. Netea et al.   Cell Host & Microbe

Anti-inflammatory Trained Immunity Mediated by Helminth Products Attenuates the Induction of T Cell-Mediated Autoimmune Disease

(2019) Shauna M. Quinn et al.   Frontiers in Immunology

Disparate Tuberculosis Disease Development in Macaque Species Is Associated With Innate Immunity

(2019) Karin Dijkman et al.   Frontiers in Immunology

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

(2018) Ioannis Mitroulis et al.   CELL

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

(2018) Eva Kaufmann et al.   CELL

Interferon stimulation creates chromatin marks and establishes transcriptional memory

(2018) Rui Kamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes

(2018) Nicole C. Howard et al.   Nature Microbiology

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance

(2018) Mounia S. Braza et al.   IMMUNITY

Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection

(2018) Paula Saz-Leal et al.   Cell Reports

Sepsis Induces a Long-Lasting State of Trained Immunity in Bone Marrow Monocytes

(2018) Katharina Bomans et al.   Frontiers in Immunology

Redefining Memory: Building the Case for Adaptive NK Cells

(2017) Silke Paust et al.   JOURNAL OF VIROLOGY

Inflammasome-Dependent Induction of Adaptive NK Cell Memory

(2016) Jasper G. van den Boorn et al.   IMMUNITY

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Molecular Mechanisms That Underlie the Dynamic Adaptation of Innate Monocyte Memory to Varying Stimulant Strength of TLR Ligands

(2016) Ruoxi Yuan et al.   Frontiers in Immunology

Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function

(2015) Heinrich Schlums et al.   IMMUNITY

Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses

(2010) Silke Paust et al.   NATURE IMMUNOLOGY

Stimulation of dendritic cells via the dectin-1/Syk pathway allows priming of cytotoxic T-cell responses

(2008) S. LeibundGut-Landmann et al.   BLOOD