Anti-inflammatory Trained Immunity Mediated by Helminth Products Attenuates the Induction of T Cell-Mediated Autoimmune Disease

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

(2018) Eva Kaufmann et al.   CELL

Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis

(2018) Aoife M. McGinley et al.   JOURNAL OF AUTOIMMUNITY

Cutting Edge:Plasmodium falciparumInduces Trained Innate Immunity

(2018) Jacob E. Schrum et al.   JOURNAL OF IMMUNOLOGY

Innate immune memory in the brain shapes neurological disease hallmarks

(2018) Ann-Christin Wendeln et al.   NATURE

Schistosoma japonicum soluble egg antigen inhibits TNF-α-induced IL-34 expression in hepatic stellate cells

(2018) Liuting Chen et al.   PARASITOLOGY RESEARCH

Soluble Egg Antigen Activates M2 Macrophages via the STAT6 and PI3K Pathways, and Schistosoma Japonicum Alternatively Activates Macrophage Polarization to Improve the Survival Rate of Septic Mice

(2017) Hao Tang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver

(2017) Carlos M. Minutti et al.   SCIENCE

Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease

(2017) Caroline E. Sutton et al.   Nature Communications

Helminth-induced Ly6Chi monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis

(2017) Cesar Terrazas et al.   Scientific Reports

In VitroExperimental Model of Trained Innate Immunity in Human Primary Monocytes

(2016) Siroon Bekkering et al.   Clinical and Vaccine Immunology

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

The cells that mediate innate immune memory and their functional significance in inflammatory and infectious diseases

(2016) Clair M. Gardiner et al.   SEMINARS IN IMMUNOLOGY

Immunometabolic Pathways in BCG-Induced Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Reports

Alternatively Activated Mononuclear Phagocytes from the Skin Site of Infection and the Impact of IL-4Rα Signalling on CD4+T Cell Survival in Draining Lymph Nodes after Repeated Exposure to Schistosoma mansoni Cercariae

(2016) Catriona T. Prendergast et al.   PLoS Neglected Tropical Diseases

The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ

(2016) Russell J. Eason et al.   Scientific Reports

Human helminth therapy to treat inflammatory disorders- where do we stand?

(2015) Helena Helmby   BMC IMMUNOLOGY

Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease

(2015) John Croese et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Helminth Products Protect against Autoimmunity via Innate Type 2 Cytokines IL-5 and IL-33, Which Promote Eosinophilia

(2015) Conor M. Finlay et al.   JOURNAL OF IMMUNOLOGY

Innate immune memory: a paradigm shift in understanding host defense

(2015) Mihai G Netea et al.   NATURE IMMUNOLOGY

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct

(2014) U. M. Gundra et al.   BLOOD

Innate IFN-γ promotes development of experimental autoimmune encephalomyelitis: A role for NK cells and M1 macrophages

(2014) Lara S. Dungan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of regulatory cells by helminth parasites: exploitation for the treatment of inflammatory diseases

(2014) Conor M. Finlay et al.   IMMUNOLOGICAL REVIEWS

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Evolutionary Roots of Arginase Expression and Regulation

(2014) Jolanta Maria Dzik   Frontiers in Immunology

Systemic signaling during plant defense

(2013) Aardra Kachroo et al.   CURRENT OPINION IN PLANT BIOLOGY

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Helminth Infections and Host Immune Regulation

(2012) H. J. McSorley et al.   CLINICAL MICROBIOLOGY REVIEWS

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

(2012) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Helminth Antigens Enable CpG-Activated Dendritic Cells to Inhibit the Symptoms of Collagen-induced Arthritis through Foxp3+ Regulatory T Cells

(2012) Franco Carranza et al.   PLoS One

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probiotic helminth administration in relapsing–remitting multiple sclerosis: a phase 1 study

(2011) JO Fleming et al.   Multiple Sclerosis Journal

Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

(2010) E. E. B. Ghosn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemocyte Differentiation Mediates Innate Immune Memory in Anopheles gambiae Mosquitoes

(2010) Janneth Rodrigues et al.   SCIENCE

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

The Fasciola hepatica Tegumental Antigen Suppresses Dendritic Cell Maturation and Function

(2009) C. M. Hamilton et al.   INFECTION AND IMMUNITY

Omega-1, a glycoprotein secreted bySchistosoma mansonieggs, drives Th2 responses

(2009) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Infection with a Helminth Parasite Attenuates Autoimmunity through TGF- -Mediated Suppression of Th17 and Th1 Responses

(2009) K. P. Walsh et al.   JOURNAL OF IMMUNOLOGY

Retnla (Relmα/Fizz1) Suppresses Helminth-Induced Th2-Type Immunity

(2009) John T. Pesce et al.   PLoS Pathogens

Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators

(2008) Yoshio Osada et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response

(2008) Xueping Zheng et al.   JOURNAL OF NEUROIMMUNOLOGY