Comprehensive molecular characterization of mitochondrial genomes in human cancers

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

(2020) Esther Rheinbay et al.   NATURE

Pan-cancer analysis of whole genomes

(2020)   NATURE

Patterns of somatic structural variation in human cancer genomes

(2020) Yilong Li et al.   NATURE

Mitochondrial mutations drive prostate cancer aggression

(2017) Julia F. Hopkins et al.   Nature Communications

Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma

(2017) Vinodh Srinivasainagendra et al.   Genome Medicine

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

(2016) Nicholas J. Haradhvala et al.   CELL

Mitochondria and Cancer

(2016) Wei-Xing Zong et al.   MOLECULAR CELL

Mitochondrial DNA copy number variation across human cancers

(2016) Ed Reznik et al.   eLife

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

(2015) Young Seok Ju et al.   GENOME RESEARCH

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis

(2015) Shilpy Joshi et al.   Cell Reports

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

(2015) James B. Stewart et al.   PLoS Genetics

The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

(2014) Caleb F. Davis et al.   CANCER CELL

Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine

(2014) Eliezer M Van Allen et al.   NATURE MEDICINE

The genomic landscape of polymorphic human nuclear mitochondrial insertions

(2014) Gargi Dayama et al.   NUCLEIC ACIDS RESEARCH

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

(2014) Young Seok Ju et al.   eLife

The regulation of mitochondrial DNA copy number in glioblastoma cells

(2013) A Dickinson et al.   CELL DEATH AND DIFFERENTIATION

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation

(2013) Maura Costello et al.   NUCLEIC ACIDS RESEARCH

Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage

(2013) Scott R. Kennedy et al.   PLoS Genetics

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Human mitochondrial DNA: roles of inherited and somatic mutations

(2012) Eric A. Schon et al.   NATURE REVIEWS GENETICS

Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans

(2012) Amanda S. Bess et al.   NUCLEIC ACIDS RESEARCH

Spectrum of somatic mitochondrial mutations in five cancers

(2012) T. C. Larman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The reference human nuclear mitochondrial sequences compilation validated and implemented on the UCSC genome browser

(2011) Domenico Simone et al.   BMC GENOMICS

The Human Mitochondrial Transcriptome

(2011) Tim R. Mercer et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Learning from oncocytic tumors: Why choose inefficient mitochondria?

(2010) Giuseppe Gasparre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial DNA sequences are present inside nuclear DNA in rat tissues and increase with age

(2010) Pilar Caro et al.   MITOCHONDRION

Allele-specific copy number analysis of tumors

(2010) P. Van Loo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial DNA Damage Initiates a Cell Cycle Arrest by a Chk2-associated Mechanism in Mammalian Cells

(2009) Christopher A. Koczor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

The intra-nucleus integration of mitochondrial DNA (mtDNA)in cervical mucosa cells and its relation with c-myc expression

(2008) Daozhen Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH