Efficient, continuous mutagenesis in human cells using a pseudo-random DNA editor

A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo

(2018) Christopher L. Moore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CasPER, a method for directed evolution in genomic contexts using mutagenesis and CRISPR/Cas9

(2018) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Simultaneous lineage tracing and cell-type identification using CRISPR–Cas9-induced genetic scars

(2018) Bastiaan Spanjaard et al.   NATURE BIOTECHNOLOGY

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

(2018) Shakked O. Halperin et al.   NATURE

Emerging applications for DNA writers and molecular recorders

(2018) Fahim Farzadfard et al.   SCIENCE

Scalable, Continuous Evolution of Genes at Mutation Rates above Genomic Error Thresholds

(2018) Arjun Ravikumar et al.   CELL

CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming

(2018) Yanxia Liu et al.   Cell Stem Cell

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Automatic thresholding from the gradients of region boundaries

(2016) G. LANDINI et al.   JOURNAL OF MICROSCOPY

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

(2016) Gaelen T Hess et al.   NATURE METHODS

GFP to BFP Conversion: A Versatile Assay for the Quantification of CRISPR/Cas9-mediated Genome Editing

(2016) Astrid Glaser et al.   Molecular Therapy-Nucleic Acids

A CRISPR-Cas9 Assisted Non-Homologous End-Joining Strategy for One-step Engineering of Bacterial Genome

(2016) Tianyuan Su et al.   Scientific Reports

Insight into biases and sequencing errors for amplicon sequencing with the Illumina MiSeq platform

(2015) Melanie Schirmer et al.   NUCLEIC ACIDS RESEARCH

A Novel Trafficking Signal within the HLA-C Cytoplasmic Tail Allows Regulated Expression upon Differentiation of Macrophages

(2014) M. R. Schaefer et al.   JOURNAL OF IMMUNOLOGY

Mutants with higher stability and specific activity from a single thermosensitive variant of T7 RNA polymerase

(2013) J.-C. Boulain et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

A system for the continuous directed evolution of biomolecules

(2011) Kevin M. Esvelt et al.   NATURE