Effects of Manganese Porphyrins on Cellular Sulfur Metabolism

Thiol regulation by Mn porphyrins, commonly known as SOD mimics

(2019) Ines Batinic-Haberle et al.   Redox Biology

Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism

(2019) Kenneth R. Olson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inorganic Polysulfides and Related Reactive Sulfur–Selenium Species from the Perspective of Chemistry

(2019) Ammar Kharma et al.   MOLECULES

Extended hypoxia‐mediated H 2 S production provides for long‐term oxygen sensing

(2019) Kenneth R. Olson et al.   Acta Physiologica

Are the beneficial effects of ‘antioxidant’ lipoic acid mediated through metabolism of reactive sulfur species?

(2019) Kenneth R. Olson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide

(2019) Kenneth R. Olson et al.   Antioxidants

Mn porphyrin-based redox-active drugs – Differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury

(2018) Ines Batinic-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate

(2018) Artak Tovmasyan et al.   ANTIOXIDANTS & REDOX SIGNALING

Alternative pathway of H 2 S and polysulfides production from sulfurated catalytic-cysteine of reaction intermediates of 3-mercaptopyruvate sulfurtransferase

(2018) Noriyuki Nagahara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

H 2 S and polysulfide metabolism: Conventional and unconventional pathways

(2018) Kenneth R. Olson   BIOCHEMICAL PHARMACOLOGY

Persulfide synthases that are functionally coupled with translation mediate sulfur respiration in mammalian cells

(2018) Shigemoto Fujii et al.   BRITISH JOURNAL OF PHARMACOLOGY

The reaction of hydrogen sulfide with disulfides: formation of a stable trisulfide and implications for biological systems

(2018) Christopher L Bianco et al.   BRITISH JOURNAL OF PHARMACOLOGY

Goodbye to S2− in aqueous solution

(2018) P. M. May et al.   CHEMICAL COMMUNICATIONS

Biological hydropersulfides and related polysulfides - a new concept and perspective in redox biology

(2018) Jon M. Fukuto et al.   FEBS LETTERS

Metabolism of hydrogen sulfide (H 2 S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase

(2018) Kenneth R. Olson et al.   Redox Biology

A selective and sensitive method for quantification of endogenous polysulfide production in biological samples

(2018) Sofia-Iris Bibli et al.   Redox Biology

Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans

(2018) Thomas P. Keeley et al.   PHYSIOLOGICAL REVIEWS

Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues

(2017) Zrinka Rajic et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cysteine persulfides and polysulfides produced by exchange reactions with H 2 S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

(2017) Shin Koike et al.   Redox Biology

Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

(2017) Helmut Sies   Redox Biology

Neglected role of hydrogen sulfide in sulfur mustard poisoning: Keap1 S-sulfhydration and subsequent Nrf2 pathway activation

(2017) Wenqi Meng et al.   Scientific Reports

Garlic oil polysulfides: H2S- and O2-independent prooxidants in buffer and antioxidants in cells

(2016) Eric R. DeLeon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen Sulfide as an Oxygen Sensor

(2015) Kenneth R. Olson   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen sulphide induces HIF-1α and Nrf2 in THP-1 macrophages

(2015) Lilian Lohninger et al.   BIOCHIMIE

Anticancer therapeutic potential of Mn porphyrin/ascorbate system

(2015) Artak Tovmasyan et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Bright Fluorescent Probe for H2S Enables Analyte-Responsive, 3D Imaging in Live Zebrafish Using Light Sheet Fluorescence Microscopy

(2015) Matthew D. Hammers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins – From superoxide dismutation to H 2 O 2 -driven pathways

(2015) Ines Batinic-Haberle et al.   Redox Biology

Hydrogen sulfide protected gastric epithelial cell from ischemia/reperfusion injury by Keap1 s-sulfhydration, MAPK dependent anti-apoptosis and NF-κB dependent anti-inflammation pathway

(2014) Cheng Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: Implications of their possible biological activity and utility

(2014) Katsuhiko Ono et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology

(2014) John Toohey et al.   MOLECULES

Controversies and conundrums in hydrogen sulfide biology

(2014) Kenneth R. Olson et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen peroxide sensing, signaling and regulation of transcription factors

(2014) H. Susana Marinho et al.   Redox Biology

Thiosulfate: a readily accessible source of hydrogen sulfide in oxygen sensing

(2013) Kenneth R. Olson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Polysulfide exerts a protective effect against cytotoxicity caused byt-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells

(2013) Shin Koike et al.   FEBS LETTERS

Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death

(2013) Myron K. Evans et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rapid Measurement of Intracellular Unbound Drug Concentrations

(2013) André Mateus et al.   MOLECULAR PHARMACEUTICS

New fluorescent probes for sulfane sulfurs and the application in bioimaging

(2013) Wei Chen et al.   Chemical Science

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

(2012) Guangdong Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

The Gasotransmitter Hydrogen Sulfide Induces Nrf2-Target Genes by Inactivating the Keap1 Ubiquitin Ligase Substrate Adaptor Through Formation of a Disulfide Bond Between Cys-226 and Cys-613

(2012) John M. Hourihan et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide

(2011) Yoshinori Mikami et al.   BIOCHEMICAL JOURNAL

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING