R2‐P2 rapid‐robotic phosphoproteomics enables multidimensional cell signaling studies

Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation.

(2019) Tanveer Singh Batth et al.   MOLECULAR & CELLULAR PROTEOMICS

Thesaurus: quantifying phosphopeptide positional isomers

(2019) Brian C. Searle et al.   NATURE METHODS

Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics

(2018) Sophie Moggridge et al.   JOURNAL OF PROTEOME RESEARCH

Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC)

(2018) Katarzyna Buczak et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

(2018) Roberta Cagnetta et al.   NEURON

High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform

(2018) Sean J. Humphrey et al.   Nature Protocols

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry

(2018) Brian C. Searle et al.   Nature Communications

Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range

(2017) Malte Sielaff et al.   JOURNAL OF PROTEOME RESEARCH

Identification of Maturation-Specific Proteins by Single-Cell Proteomics of Human Oocytes

(2016) Irma Virant-Klun et al.   MOLECULAR & CELLULAR PROTEOMICS

Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes

(2016) Jennifer G. Abelin et al.   MOLECULAR & CELLULAR PROTEOMICS

Plug-and-play analysis of the human phosphoproteome by targeted high-resolution mass spectrometry

(2016) Robert T Lawrence et al.   NATURE METHODS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics

(2015) Sean J Humphrey et al.   NATURE BIOTECHNOLOGY

Dynamic phosphoproteomics reveals TORC1-dependent regulation of yeast nucleotide and amino acid biosynthesis

(2015) A. P. Oliveira et al.   Science Signaling

A Cell-Signaling Network Temporally Resolves Specific versus Promiscuous Phosphorylation

(2015) Evgeny Kanshin et al.   Cell Reports

Dynamic phosphoproteomics reveals TORC1-dependent regulation of yeast nucleotide and amino acid biosynthesis

(2015) A. P. Oliveira et al.   Science Signaling

Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC

(2014) Christopher J. Tape et al.   ANALYTICAL CHEMISTRY

Comprehensive and Reproducible Phosphopeptide Enrichment Using Iron Immobilized Metal Ion Affinity Chromatography (Fe-IMAC) Columns

(2014) Benjamin Ruprecht et al.   MOLECULAR & CELLULAR PROTEOMICS

Phosphoproteomic analyses reveal novel cross-modulation mechanisms between two signaling pathways in yeast

(2014) S. Vaga et al.   Molecular Systems Biology

Ultrasensitive proteome analysis using paramagnetic bead technology

(2014) C. S. Hughes et al.   Molecular Systems Biology

A sentinel protein assay for simultaneously quantifying cellular processes

(2014) Martin Soste et al.   NATURE METHODS

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

The Regulation of Filamentous Growth in Yeast

(2012) Paul J. Cullen et al.   GENETICS

A cross-platform toolkit for mass spectrometry and proteomics

(2012) Matthew C Chambers et al.   NATURE BIOTECHNOLOGY

Comet: An open-source MS/MS sequence database search tool

(2012) Jimmy K. Eng et al.   PROTEOMICS

Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L

(2011) Alexandre Huber et al.   EMBO JOURNAL

The TEA Transcription Factor Tec1 Links TOR and MAPK Pathways to Coordinate Yeast Development

(2011) Stefan Brückner et al.   GENETICS

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

The TEA Transcription Factor Tec1 Confers Promoter-Specific Gene Regulation by Ste12-Dependent and -Independent Mechanisms

(2010) Barbara Heise et al.   EUKARYOTIC CELL

Magnetic Bead Processor for Rapid Evaluation and Optimization of Parameters for Phosphopeptide Enrichment

(2009) Scott B. Ficarro et al.   ANALYTICAL CHEMISTRY

Multisite Phosphorylation of theSaccharomyces cerevisiaeFilamentous Growth Regulator Tec1 Is Required for its Recognition by the E3 Ubiquitin Ligase Adaptor Cdc4 and Its Subsequent Destruction In Vivo

(2009) Marie Z. Bao et al.   EUKARYOTIC CELL

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

(2009) A. Huber et al.   GENES & DEVELOPMENT