A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles

The role of lysosomes and autophagosomes in frontotemporal lobar degeneration

(2018) H. D. C. Bain et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Reactive astrocytes in Alzheimer’s disease: A double-edged sword

(2018) Heejung Chun et al.   NEUROSCIENCE RESEARCH

An Alzheimer's Disease-Linked Loss-of-Function CLN5 Variant Impairs Cathepsin D Maturation, Consistent with a Retromer Trafficking Defect

(2018) Yasir H. Qureshi et al.   MOLECULAR AND CELLULAR BIOLOGY

Endosomal sorting and trafficking, the retromer complex and neurodegeneration

(2018) Alana N. Vagnozzi et al.   MOLECULAR PSYCHIATRY

Brain mechanisms controlling Pavlovian fear conditioning.

(2018) Joanna O. Y. Yau et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology

(2017) Jian-Guo Li et al.   HUMAN MOLECULAR GENETICS

The retromer complex system in a transgenic mouse model of AD: influence of age

(2017) Jin Chu et al.   NEUROBIOLOGY OF AGING

The direct role of 5-lipoxygenase on tau pathology, synaptic integrity and cognition in a mouse model of tauopathy

(2017) Alana N. Vagnozzi et al.   Translational Psychiatry

Extra-virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy

(2017) Elisabetta Lauretti et al.   Annals of Clinical and Translational Neurology

Synaptic pathology: A shared mechanism in neurological disease

(2016) Christopher M. Henstridge et al.   AGEING RESEARCH REVIEWS

Retromer-Mediated Protein Sorting and Vesicular Trafficking

(2016) Jia-Jia Liu   Journal of Genetics and Genomics

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein

(2016) Timothy Y. Huang et al.   JOURNAL OF NEUROSCIENCE

Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy

(2015) Phillip F. Giannopoulos et al.   BIOLOGICAL PSYCHIATRY

Maternal dexamethasone exposure ameliorates cognition and tau pathology in the offspring of triple transgenic AD mice

(2015) A Di Meco et al.   MOLECULAR PSYCHIATRY

Behavioral assays with mouse models of Alzheimer's disease: Practical considerations and guidelines

(2014) Daniela Puzzo et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacological chaperones stabilize retromer to limit APP processing

(2014) Vincent J Mecozzi et al.   Nature Chemical Biology

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

(2012) A. W. Fjorback et al.   JOURNAL OF NEUROSCIENCE

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production

(2012) Jeremy H. Herskowitz et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of Alzheimer disease-associated variants in genes that regulate retromer function

(2012) Badri N. Vardarajan et al.   NEUROBIOLOGY OF AGING

The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

(2012) Akhil Bhalla et al.   NEUROBIOLOGY OF DISEASE

Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in thetrans-Golgi network

(2012) Regina Wai-Yan Choy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

(2011) Lei Wen et al.   JOURNAL OF CELL BIOLOGY

Retromer disruption promotes amyloidogenic APP processing

(2011) Christopher P. Sullivan et al.   NEUROBIOLOGY OF DISEASE

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA