Emergence of Circulating MicroRNAs in Breast Cancer as Diagnostic and Therapeutic Efficacy Biomarkers

MicroRNA-based biosensors for early detection of cancers

(2019) Majid Rezayi et al.   CURRENT PHARMACEUTICAL DESIGN

Circulating miRNAs as a marker of metastatic disease and prognostic factor in metastatic breast cancer

(2019) Chara Papadaki et al.   Oncotarget

Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer– A Comparison

(2019) Vahid Arabkari et al.   PATHOLOGY & ONCOLOGY RESEARCH

Potential value of circulatory microRNA122 gene expression as a prognostic and metastatic prediction marker for breast cancer

(2019) Amany A. Saleh et al.   MOLECULAR BIOLOGY REPORTS

Plasma microRNA levels for predicting therapeutic response to neoadjuvant treatment in HER2-positive breast cancer: Results from the NeoALTTO trial

(2019) Serena Di Cosimo et al.   CLINICAL CANCER RESEARCH

Circulating microRNAs miR-331 and miR-195 differentiate local luminal a from metastatic breast cancer

(2019) Peter McAnena et al.   BMC CANCER

Serum MiRNA-27a as potential diagnostic nucleic marker for breast cancer

(2019) Menha Swellam et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Circulating MicroRNAs in Cancer: Potential and Challenge

(2019) Mengying Cui et al.   Frontiers in Genetics

Clinical Translatability of “Identified” Circulating miRNAs for Diagnosing Breast Cancer: Overview and Update

(2019) Grimaldi et al.   Cancers

Circulating miRNAs in Untreated Breast Cancer: An Exploratory Multimodality Morpho-Functional Study

(2019) Mariarosaria Incoronato et al.   Cancers

Circulating miRNAs as Diagnostic and Prognostic Biomarkers in Common Solid Tumors: Focus on Lung, Breast, Prostate Cancers, and Osteosarcoma

(2019) Michela Bottani et al.   Journal of Clinical Medicine

Whole blood microRNAs as potential biomarkers in post-operative early breast cancer patients

(2018) Marianna Alunni-Fabbroni et al.   BMC CANCER

Circulating microRNAs from the miR-106a–363 cluster on chromosome X as novel diagnostic biomarkers for breast cancer

(2018) Minghui Li et al.   BREAST CANCER RESEARCH AND TREATMENT

Branched rolling circle amplification method for measuring serum circulating microRNA levels for early breast cancer detection

(2018) Tingting Fan et al.   CANCER SCIENCE

Potential diagnostic role of circulating MiRNAs in breast cancer: Implications on clinicopathological characters

(2018) Menha Swellam et al.   CLINICAL BIOCHEMISTRY

Evaluation of miRNA-21 and miRNA Let-7 as Prognostic Markers in Patients With Breast Cancer

(2018) Eman A. Elghoroury et al.   Clinical Breast Cancer

Potential of Protein-based Anti-metastatic Therapy with Serpins and Inter α-Trypsin Inhibitors

(2018) ULRICH H. WEIDLE et al.   Cancer Genomics & Proteomics

Role of some circulating MiRNAs on breast cancer diagnosis

(2018) Menha Swellam et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Breast cancer identification via modeling of peripherally circulating miRNAs

(2018) Xiaomeng Cui et al.   PeerJ

Single-molecule catalytic hairpin assembly for rapid and direct quantification of circulating miRNA biomarkers

(2018) Xiuxue Hu et al.   ANALYTICA CHIMICA ACTA

Circulating Pre-microRNA-488 in Peripheral Blood Is a Potential Biomarker for Predicting Recurrence in Breast Cancer

(2018) TAKAAKI MASUDA et al.   ANTICANCER RESEARCH

MicroRNAs 182 and 375 Sera Expression as Prognostic Biochemical Markers in Breast Cancer

(2018) Ola S. Ali et al.   Clinical Breast Cancer

Serum levels of circulating miRNA-21, miRNA-10b and miRNA-200c in triple-negative breast cancer patients

(2018) Sebastian Niedźwiecki et al.   Ginekologia Polska

GLOBOCAN 2018: counting the toll of cancer

(2018) The Lancet   LANCET

Identification of serum miR-1915-3p and miR-455-3p as biomarkers for breast cancer

(2018) Jian Guo et al.   PLoS One

Dynamics of circulating microRNAs as a novel indicator of clinical response to neoadjuvant chemotherapy in breast cancer

(2018) Wenjie Zhu et al.   Cancer Medicine

In Situ Detection of Plasma Exosomal MicroRNA-1246 for Breast Cancer Diagnostics by a Au Nanoflare Probe

(2018) Ling-Yan Zhai et al.   ACS Applied Materials & Interfaces

Serum miRNA-based distinct clusters define three groups of breast cancer patients with different clinicopathological and immune characteristics

(2018) Sotirios P. Fortis et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Evaluation of miR-16 as an internal control in the patients with breast cancer

(2018) Soheil Madadi et al.   HUMAN PATHOLOGY

Clinical aspects of circulating miRNA-335 in breast cancer patients: A prospective study

(2018) Menha Swellam et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Expression of circulating miR-17, miR-25, and miR-133 in breast cancer patients

(2018) AmirReza Hesari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

The roles of oncogenic miRNAs and their therapeutic importance in breast cancer

(2017) Samia O'Bryan et al.   EUROPEAN JOURNAL OF CANCER

Identification of microRNA biomarkers in the blood of breast cancer patients based on microRNA profiling

(2017) Kai Zhang et al.   GENE

Comparison of isolation methods of exosomes and exosomal RNA from cell culture medium and serum

(2017) Yue-Ting Tang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The prognostic and therapeutic application of microRNAs in breast cancer: Tissue and circulating microRNAs

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular heterogeneity in breast cancer: State of the science and implications for patient care

(2017) Rachel E. Ellsworth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Targeting human breast cancer cells by an oncolytic adenovirus using microRNA-targeting strategy

(2017) Mohammad Shayestehpour et al.   VIRUS RESEARCH

Low Expression of Circulating MicroRNA-34c is Associated with Poor Prognosis in Triple-Negative Breast Cancer

(2017) Zhihao Zeng et al.   YONSEI MEDICAL JOURNAL

Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers

(2017) Rimi Hamam et al.   Cell Death & Disease

Development of a predictive miRNA signature for breast cancer risk among high-risk women

(2017) Nicholas H. Farina et al.   Oncotarget

Down-regulation of traditional oncomiRs in plasma of breast cancer patients

(2017) Dana Jurkovicova et al.   Oncotarget

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

(2017) Aiko Sueta et al.   Oncotarget

A novel panel of serum miR-21/miR-155/miR-365 as a potential diagnostic biomarker for breast cancer

(2017) Ji-Guang Han et al.   Annals of Surgical Treatment and Research

Circulating Cell-free miRNA Expression and its Association with Clinicopathologic Features in Inflammatory and Non-Inflammatory Breast Cancer

(2016) K Hamdi et al.   Asian Pacific Journal of Cancer Prevention

Novel combination of serum microRNA for detecting breast cancer in the early stage

(2016) Akihiko Shimomura et al.   CANCER SCIENCE

Direct Comparison of Metastasis-Related miRNAs Expression Levels in Circulating Tumor Cells, Corresponding Plasma, and Primary Tumors of Breast Cancer Patients

(2016) A. Markou et al.   CLINICAL CHEMISTRY

Identification of Circulating MicroRNA Signatures in Crohnʼs Disease Using the Nanostring nCounter Technology

(2016) Angelos Oikonomopoulos et al.   INFLAMMATORY BOWEL DISEASES

Prospective validation of a blood-based 9-miRNA profile for early detection of breast cancer in a cohort of women examined by clinical mammography

(2016) Maria B. Lyng et al.   Molecular Oncology

miR-182, of the miR-183 cluster family, is packaged in exosomes and is detected in human exosomes from serum, breast cells and prostate cells

(2016) Brittany L. Mihelich et al.   Oncology Letters

Elevated microRNA-125b levels predict a worse prognosis in HER2-positive breast cancer patients

(2016) Yanwei Luo et al.   Oncology Letters

Prognostic value of circulating microRNA-21 for breast cancer: a systematic review and meta-analysis

(2016) Wang Jinling et al.   Artificial Cells Nanomedicine and Biotechnology

Identification of Specific miRNA Signature in Paired Sera and Tissue Samples of Indian Women with Triple Negative Breast Cancer

(2016) Seema Thakur et al.   PLoS One

Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material

(2016) Victoria El-Khoury et al.   Scientific Reports

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection

(2016) Rimi Hamam et al.   Scientific Reports

Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease

(2015) Joseph Inns et al.   BREAST

A circulating miRNA signature as a diagnostic biomarker for non-invasive early detection of breast cancer

(2015) Lei Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor MicroRNA Expression Profiling Identifies Circulating MicroRNAs for Early Breast Cancer Detection

(2015) N. Matamala et al.   CLINICAL CHEMISTRY

Role of microRNAs -29b-2, −155, −197 and −205 as diagnostic biomarkers in serum of breast cancer females

(2015) Olfat Shaker et al.   GENE

Pilot Study of Serum MicroRNA-21 as a Diagnostic and Prognostic Biomarker in Egyptian Breast Cancer Patients

(2015) Eman A. Toraih et al.   Molecular Diagnosis & Therapy

Reduced expression levels of let-7c in human breast cancer patients

(2015) XIN-XIN LI et al.   Oncology Letters

Circulating microRNA-based screening tool for breast cancer

(2015) Pierre Frères et al.   Oncotarget

Absolute quantification of cell-free microRNAs in cancer patients

(2015) Manuela Ferracin et al.   Oncotarget

Lin28b Promotes Head and Neck Cancer Progression via Modulation of the Insulin-Like Growth Factor Survival Pathway

(2015) Nehad M Alajez et al.   Oncotarget

MicroRNA-484 is more highly expressed in serum of early breast cancer patients compared to healthy volunteers

(2014) Silvia Zearo et al.   BMC CANCER

Oncogenic MicroRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum

(2014) Marek Sochor et al.   BMC CANCER

Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases

(2014) S A Joosse et al.   BRITISH JOURNAL OF CANCER

A Serum MicroRNA Signature Predicts Tumor Relapse and Survival in Triple-Negative Breast Cancer Patients

(2014) K. Kleivi Sahlberg et al.   CLINICAL CANCER RESEARCH

The validity of circulating microRNAs in oncology: Five years of challenges and contradictions

(2014) J. Jarry et al.   Molecular Oncology

Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: A case control study

(2014) Annette R. Kodahl et al.   Molecular Oncology

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High Serum miR-19a Levels Are Associated with Inflammatory Breast Cancer and Are Predictive of Favorable Clinical Outcome in Patients with Metastatic HER2+ Inflammatory Breast Cancer

(2014) Simone Anfossi et al.   PLoS One

Impact of Tumour Epithelial Subtype on Circulating microRNAs in Breast Cancer Patients

(2014) Peadar S. Waters et al.   PLoS One

Identification and Validation of Oncologic miRNA Biomarkers for Luminal A-like Breast Cancer

(2014) Ailbhe M. McDermott et al.   PLoS One

Circulating MicroRNAs as Easy-to-Measure Aging Biomarkers in Older Breast Cancer Patients: Correlation with Chronological Age but Not with Fitness/Frailty Status

(2014) Sigrid Hatse et al.   PLoS One

miRNAs in Sera of Tunisian patients discriminate between inflammatory breast cancer and non-inflammatory breast cancer

(2014) Khouloud Hamdi et al.   SpringerPlus

microRNAs in breast cancer development and treatment

(2013) Danila Serpico et al.   CANCER TREATMENT REVIEWS

Identification of Circulating MicroRNA Signatures for Breast Cancer Detection

(2013) M. Chan et al.   CLINICAL CANCER RESEARCH

Deregulated Serum Concentrations of Circulating Cell-Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression

(2013) C. Eichelser et al.   CLINICAL CHEMISTRY

Serum Circulating microRNA Profiling for Identification of Potential Breast Cancer Biomarkers

(2013) Fermín Mar-Aguilar et al.   DISEASE MARKERS

Serum Overexpression of MicroRNA-10b in Patients with Bone Metastatic Primary Breast Cancer

(2013) F-L Zhao et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Down-regulation of miRNA-30a in human plasma is a novel marker for breast cancer

(2013) Rui-chao Zeng et al.   MEDICAL ONCOLOGY

MicroRNA-30a suppresses breast tumor growth and metastasis by targeting metadherin

(2013) N Zhang et al.   ONCOGENE

Circulating microRNAs as Specific Biomarkers for Breast Cancer Detection

(2013) Enders K. O. Ng et al.   PLoS One

Plasma MicroRNA Panel for Minimally Invasive Detection of Breast Cancer

(2013) Katarina Cuk et al.   PLoS One

Higher expression of circulating miR-182 as a novel biomarker for breast cancer

(2013) PING-YU WANG et al.   Oncology Letters

Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients

(2012) Heidi Schwarzenbach et al.   BREAST CANCER RESEARCH AND TREATMENT

The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality

(2012) Danny R. Youlden et al.   Cancer Epidemiology

Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls

(2012) Zhibin Hu et al.   CARCINOGENESIS

Analysis of serum genome-wide microRNAs for breast cancer detection

(2012) Qian Wu et al.   CLINICA CHIMICA ACTA

MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1

(2012) Laisheng Li et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer

(2012) D. Madhavan et al.   CLINICAL CANCER RESEARCH

Decreased serum miR-181a is a potential new tool for breast cancer screening

(2012) LI-JUAN GUO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

High Expression of MicroRNA-210 is an Independent Factor Indicating a Poor Prognosis in Japanese Triple-negative Breast Cancer Patients

(2012) T. Toyama et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer

(2012) Haiyan Si et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

(2012) Xiwei Wu et al.   Journal of Translational Medicine

Genome-wide screen for aberrantly expressed miRNAs reveals miRNA profile signature in breast cancer

(2012) Li Guo et al.   MOLECULAR BIOLOGY REPORTS

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection

(2012) Michael G. Schrauder et al.   PLoS One

Circulating MiR-125b as a Marker Predicting Chemoresistance in Breast Cancer

(2012) Hongjiang Wang et al.   PLoS One

Serum MicroRNA-155 as a Potential Biomarker to Track Disease in Breast Cancer

(2012) Yu Sun et al.   PLoS One

The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers

(2012) Weijie Chen et al.   TUMOR BIOLOGY

Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients

(2011) Eun-Jung Jung et al.   CANCER

miR-218 Suppresses Nasopharyngeal Cancer Progression through Downregulation of Survivin and the SLIT2-ROBO1 Pathway

(2011) N. M. Alajez et al.   CANCER RESEARCH

MicroRNA-301 Mediates Proliferation and Invasion in Human Breast Cancer

(2011) W. Shi et al.   CANCER RESEARCH

Analysis of Circulating MicroRNA: Preanalytical and Analytical Challenges

(2011) J. S. McDonald et al.   CLINICAL CHEMISTRY

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer

(2011) K. J. Png et al.   GENES & DEVELOPMENT

MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development

(2011) Holger Heyn et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-200c Represses Migration and Invasion of Breast Cancer Cells by Targeting Actin-Regulatory Proteins FHOD1 and PPM1F

(2011) S. Jurmeister et al.   MOLECULAR AND CELLULAR BIOLOGY

Haemolysis during Sample Preparation Alters microRNA Content of Plasma

(2011) Michaela B. Kirschner et al.   PLoS One

Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype

(2010) I Van der Auwera et al.   BRITISH JOURNAL OF CANCER

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

(2010) P. J. O'Donovan et al.   CARCINOGENESIS

Direct Serum Assay for MicroRNA-21 Concentrations in Early and Advanced Breast Cancer

(2010) S. Asaga et al.   CLINICAL CHEMISTRY

Correlation and quantitation of microRNA aberrant expression in tissues and sera from patients with breast tumor

(2010) Fengjun Wang et al.   GYNECOLOGIC ONCOLOGY

Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR)

(2010) Evan M. Kroh et al.   METHODS

Systemic miRNA-195 Differentiates Breast Cancer from Other Malignancies and Is a Potential Biomarker for Detecting Noninvasive and Early Stage Disease

(2010) H. M. Heneghan et al.   ONCOLOGIST

A Pilot Study of Circulating miRNAs as Potential Biomarkers of Early Stage Breast Cancer

(2010) Hua Zhao et al.   PLoS One

miR-155 gene: A typical multifunctional microRNA

(2009) Isabella Faraoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

microRNA-205 Regulates HER3 in Human Breast Cancer

(2009) M. V. Iorio et al.   CANCER RESEARCH

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

Suppression of cell growth and invasion by miR-205 in breast cancer

(2009) Hailong Wu et al.   CELL RESEARCH

Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets

(2009) J. Hausser et al.   GENOME RESEARCH

MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets

(2009) Raffaele Baffa et al.   JOURNAL OF PATHOLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells

(2009) Nalinie S. Wickramasinghe et al.   NUCLEIC ACIDS RESEARCH

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY

High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1

(2008) Biyun Qian et al.   BREAST CANCER RESEARCH AND TREATMENT

A truth serum for cancer — microRNAs have major potential as cancer biomarkers

(2008) Lena J Chin et al.   CELL RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

(2008) J. J. Forman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA