Dysregulation of BDNF/TrkB signaling mediated by NMDAR/Ca2+/calpain might contribute to postoperative cognitive dysfunction in aging mice

NLRP3 inflammasome in NMDA-induced retinal excitotoxicity

(2019) Pavlina Tsoka et al.   EXPERIMENTAL EYE RESEARCH

Prevention of excitotoxicity‐induced processing of BDNF receptor TrkB‐FL leads to stroke neuroprotection

(2019) Gonzalo S Tejeda et al.   EMBO Molecular Medicine

Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer’s Disease

(2019) Zhi-Hao Wang et al.   Cell Reports

Memantine Mitigates Oligodendrocyte Damage after Repetitive Mild Traumatic Brain Injury

(2019) Guixian Ma et al.   NEUROSCIENCE

N-methyl-D-aspartate receptor–mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease

(2018) Erin J. Kodis et al.   Alzheimers & Dementia

TEMPORARY REMOVAL: Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018

(2018) L. Evered et al.   BRITISH JOURNAL OF ANAESTHESIA

Protection against TBI-Induced Neuronal Death with Post-Treatment with a Selective Calpain-2 Inhibitor in Mice

(2018) Yubin Wang et al.   JOURNAL OF NEUROTRAUMA

Deletion of the endogenous TrkB.T1 receptor isoform restores the number of hippocampal CA1 parvalbumin-positive neurons and rescues long-term potentiation in pre-symptomatic mSOD1(G93A) ALS mice

(2018) Eros Quarta et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals

(2018) Ashok Kumar et al.   NEUROBIOLOGY OF AGING

Calpastatin ablation aggravates the molecular phenotype in cell and animal models of Huntington disease

(2018) Jonasz Jeremiasz Weber et al.   NEUROPHARMACOLOGY

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

(2018) Sara R. Tanqueiro et al.   Frontiers in Pharmacology

Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018

(2018) Lis Evered et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Recommendations for the Nomenclature of Cognitive Change Associated With Anaesthesia and Surgery—2018

(2018) L. Evered et al.   ANESTHESIA AND ANALGESIA

Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery—2018

(2018) L. Evered et al.   ANESTHESIOLOGY

Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery—2018

(2018) L. Evered et al.   Canadian Journal of Anesthesia-Journal canadien d anesthesie

Recommendations for the Nomenclature of Cognitive Change Associated with Anaesthesia and Surgery—20181

(2018) L. Evered et al.   JOURNAL OF ALZHEIMERS DISEASE

Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury

(2017) Jessica J. Matyas et al.   JOURNAL OF NEUROSCIENCE

Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery

(2017) Teresa Femenía et al.   JOURNAL OF NEUROSCIENCE

Calpain-Dependent Degradation of Nucleoporins Contributes to Motor Neuron Death in a Mouse Model of Chronic Excitotoxicity

(2017) Kaori Sugiyama et al.   JOURNAL OF NEUROSCIENCE

NADPH oxidase 2-derived reactive oxygen species in the hippocampus might contribute to microglial activation in postoperative cognitive dysfunction in aged mice

(2016) Li-Li Qiu et al.   BRAIN BEHAVIOR AND IMMUNITY

Brain ischaemia induces shedding of a BDNF-scavenger ectodomain from TrkB receptors by excitotoxicity activation of metalloproteinases and γ-secretases

(2016) Gonzalo S Tejeda et al.   JOURNAL OF PATHOLOGY

Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes

(2016) Víctor Danelon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

MPTP-induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF-TrkB pathway

(2015) Guoqi Zhu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, attenuates postoperative cognitive dysfunction in aging mice

(2015) Min Jia et al.   Frontiers in Molecular Neuroscience

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

(2014) André Jerónimo-Santos et al.   CEREBRAL CORTEX

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

(2014) Joshua L. Plotkin et al.   NEURON

Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus

(2014) Jinhua Ma et al.   Molecular Brain

Alteration in BDNF and its receptors, full-length and truncated TrkB and p75NTR following penetrating traumatic brain injury

(2013) Elham Rostami et al.   BRAIN RESEARCH

Critical role of calpain in spinal cord degeneration in Parkinson's disease

(2013) Supriti Samantaray et al.   JOURNAL OF NEUROCHEMISTRY

NMDA Receptor Activation and Calpain Contribute to Disruption of Dendritic Spines by the Stress Neuropeptide CRH

(2013) Adrienne L. Andres et al.   JOURNAL OF NEUROSCIENCE

Postoperative pain impairs subsequent performance on a spatial memory task via effects on N-methyl-d-aspartate receptor in aged rats

(2013) Haidong Chi et al.   LIFE SCIENCES

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Class I Histone Deacetylase Inhibitor Valproic Acid Reverses Cognitive Deficits in a Mouse Model of Septic Encephalopathy

(2013) Jing Wu et al.   NEUROCHEMICAL RESEARCH

Thinking through postoperative cognitive dysfunction: How to bridge the gap between clinical and pre-clinical perspectives

(2012) Iris B. Hovens et al.   BRAIN BEHAVIOR AND IMMUNITY

Calpain and STriatal-Enriched protein tyrosine Phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model

(2012) C. M. Gladding et al.   HUMAN MOLECULAR GENETICS

Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons

(2012) J. R. Gomes et al.   JOURNAL OF NEUROSCIENCE

Developmental traumatic brain injury decreased brain derived neurotrophic factor expression late after injury

(2012) Michelle Elena Schober et al.   METABOLIC BRAIN DISEASE

Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity

(2012) Ó G Vidaurre et al.   Cell Death & Disease

Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

(2011) I.L. Ferreira et al.   CELL CALCIUM

Perioperative Cognitive Decline in the Aging Population

(2011) Niccolò Terrando et al.   MAYO CLINIC PROCEEDINGS

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

A Pharmacological Analysis of the Neuroprotective Efficacy of the Brain- and Cell-Permeable Calpain Inhibitor MDL-28170 in the Mouse Controlled Cortical Impact Traumatic Brain Injury Model

(2010) Stephanie N. Thompson et al.   JOURNAL OF NEUROTRAUMA

The prevalence of cognitive dysfunction after conventional and computer-assisted total knee replacement

(2010) H. Deo et al.   KNEE

Endogenous Truncated TrkB.T1 Receptor Regulates Neuronal Complexity and TrkB Kinase Receptor Function In Vivo

(2009) L. Carim-Todd et al.   JOURNAL OF NEUROSCIENCE

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS

Isoflurane-Induced Caspase-3 Activation Is Dependent on Cytosolic Calcium and Can Be Attenuated by Memantine

(2008) G. Zhang et al.   JOURNAL OF NEUROSCIENCE