Early postnatal manganese exposure causes arousal dysregulation and lasting hypofunctioning of the prefrontal cortex catecholaminergic systems

Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells

(2019) Souvarish Sarkar et al.   Science Signaling

PET imaging of dopamine release in the frontal cortex of manganese‐exposed non‐human primates

(2019) Tomas R. Guilarte et al.   JOURNAL OF NEUROCHEMISTRY

Astrocytes, neurons, synapses: a tripartite view on cortical circuit development

(2018) Isabella Farhy-Tselnicker et al.   Neural Development

DARPP-32 in the orchestration of responses to positive natural stimuli

(2018) Simona Scheggi et al.   JOURNAL OF NEUROCHEMISTRY

Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese

(2018) Katriana A. Popichak et al.   Journal of Neuroinflammation

Versatile control of synaptic circuits by astrocytes: where, when and how?

(2018) Glenn Dallérac et al.   NATURE REVIEWS NEUROSCIENCE

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Manganese-Mediated Decrease in Levels of c-RET and Tyrosine Hydroxylase Expression In Vitro

(2017) Mayuko Y. Kumasaka et al.   NEUROTOXICITY RESEARCH

Methylphenidate alleviates manganese-induced impulsivity but not distractibility

(2017) Stephane A. Beaudin et al.   NEUROTOXICOLOGY AND TERATOLOGY

Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes

(2016) Prashant Tarale et al.   ARCHIVES OF TOXICOLOGY

Early Postnatal Manganese Exposure Causes Lasting Impairment of Selective and Focused Attention and Arousal Regulation in Adult Rats

(2016) Stephane A. Beaudin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

(2016) Tanara V. Peres et al.   Metallomics

Manganese Exposure and Neurocognitive Outcomes in Rural School-Age Children: The Communities Actively Researching Exposure Study (Ohio, USA)

(2015) Erin N. Haynes et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Impact of ferromanganese alloy plants on household dust manganese levels: Implications for childhood exposure

(2015) E.L. Lucas et al.   ENVIRONMENTAL RESEARCH

Oral Methylphenidate Alleviates the Fine Motor Dysfunction Caused by Chronic Postnatal Manganese Exposure in Adult Rats

(2015) Stéphane A. Beaudin et al.   TOXICOLOGICAL SCIENCES

Neurobehavioral Function in School-Age Children Exposed to Manganese in Drinking Water

(2014) Youssef Oulhote et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Biomarkers of Manganese Exposure in Pregnant Women and Children Living in an Agricultural Community in California

(2014) Robert B. Gunier et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of acute and chronic administration of venlafaxine and desipramine on extracellular monoamine levels in the mouse prefrontal cortex and striatum

(2014) Kosuke Higashino et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

Attention Deficit–Hyperactivity Disorder in Children and Adolescents

(2014) Heidi M. Feldman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Determinants of manganese levels in house dust samples from the CHAMACOS cohort

(2014) R.B. Gunier et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

(2013) Fabiano M. Cordova et al.   ARCHIVES OF TOXICOLOGY

Modeling Transformations of Neurodevelopmental Sequences across Mammalian Species

(2013) A. D. Workman et al.   JOURNAL OF NEUROSCIENCE

Methylation of the dopamine D2 receptor (DRD2) gene promoter in women with a bulimia-spectrum disorder: Associations with borderline personality disorder and exposure to childhood abuse

(2013) Patricia Groleau et al.   JOURNAL OF PSYCHIATRIC RESEARCH

DNA methylation regulates associative reward learning

(2013) Jeremy J Day et al.   NATURE NEUROSCIENCE

Neurocircuitry Underlying the Preferential Sensitivity of Prefrontal Catecholamines to Low-Dose Psychostimulants

(2013) Brooke E Schmeichel et al.   NEUROPSYCHOPHARMACOLOGY

Early life versus lifelong oral manganese exposure differently impairs skilled forelimb performance in adult rats

(2013) Stephane A. Beaudin et al.   NEUROTOXICOLOGY AND TERATOLOGY

The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition

(2013) Sheree F. Logue et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Neural Network Model to Translate Brain Developmental Events across Mammalian Species

(2013) Radhakrishnan Nagarajan et al.   PLoS One

Does soy-based infant formula cause ADHD? Update and public policy considerations

(2012) Francis M Crinella   Expert Review of Neurotherapeutics

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

The Prevalence of DSM-IV Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review

(2012) Erik G. Willcutt   Neurotherapeutics

Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission

(2012) Roberto G. Lucchini et al.   NEUROTOXICOLOGY

Effects of dorsal or ventral medial prefrontal cortical lesions on five-choice serial reaction time performance in rats

(2011) Jean-Marie Maddux et al.   BEHAVIOURAL BRAIN RESEARCH

Catecholamine influences on prefrontal cortical function: Relevance to treatment of attention deficit/hyperactivity disorder and related disorders

(2011) Amy F.T. Arnsten et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Intellectual Impairment in School-Age Children Exposed to Manganese from Drinking Water

(2010) Maryse F. Bouchard et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Preweaning Mn exposure leads to prolonged astrocyte activation and lasting effects on the dopaminergic system in adult male rats

(2010) Cynthia H. Kern et al.   SYNAPSE

Postnatal manganese exposure alters the expression of D2L and D2S receptor isoforms: Relationship to PKA activity and Akt levels

(2010) Sanders A. Mcdougall et al.   SYNAPSE

Extracellular norepinephrine, norepinephrine receptor and transporter protein and mRNA levels are differentially altered in the developing rat brain due to dietary iron deficiency and manganese exposure

(2009) Joel G. Anderson et al.   BRAIN RESEARCH

Toward a New Understanding of Attention-Deficit Hyperactivity Disorder Pathophysiology

(2009) Amy F.T. Arnsten   CNS DRUGS

Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels

(2009) Cynthia H. Kern et al.   SYNAPSE

Developmental Exposure to Manganese Increases Adult Susceptibility to Inflammatory Activation of Glia and Neuronal Protein Nitration

(2009) Julie A. Moreno et al.   TOXICOLOGICAL SCIENCES

Abnormal Motor Function and the Expression of Striatal Dopamine D2 Receptors in Manganese-Treated Mice

(2008) Jungmin Nam et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Double Dissociation of the Effects of Medial and Orbital Prefrontal Cortical Lesions on Attentional and Affective Shifts in Mice

(2008) G. B. Bissonette et al.   JOURNAL OF NEUROSCIENCE

Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving

(2008) Thomas Hillemacher et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Postnatal manganese exposure alters dopamine transporter function in adult rats: Potential impact on nonassociative and associative processes

(2008) S.A. McDougall et al.   NEUROSCIENCE

Manganese Induces Dopaminergic Neurodegeneration via Microglial Activation in a Rat Model of Manganism

(2008) Fang Zhao et al.   TOXICOLOGICAL SCIENCES