Macrophage polarization is linked to Ca2+-independent phospholipase A2β-derived lipids and cross-cell signaling in mice

Leukotriene Involvement in the Insulin Receptor Pathway and Macrophage Profiles in Muscles from Type 1 Diabetic Mice

(2019) João Pedro Tôrres Guimarães et al.   MEDIATORS OF INFLAMMATION

Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid

(2018) Naveen K.V. Gundala et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stress, inflammation, and eicosanoids: an emerging perspective

(2018) Sujanitha Umamaheswaran et al.   CANCER AND METASTASIS REVIEWS

Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators

(2018) Charles N. Serhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Membrane Allostery and Unique Hydrophobic Sites Promote Enzyme Substrate Specificity

(2018) Varnavas D. Mouchlis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synopsis of arachidonic acid metabolism: A review

(2018) Violette Said Hanna et al.   Journal of Advanced Research

iPLA2β and its role in male fertility, neurological disorders, metabolic disorders, and inflammation

(2018) John Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Prostaglandin E 2 restrains human Treg cell differentiation via E prostanoid receptor 2-protein kinase A signaling

(2017) Hui Li et al.   IMMUNOLOGY LETTERS

Prostaglandin E2Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1

(2017) Kirsten M. Hooper et al.   JOURNAL OF IMMUNOLOGY

Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic Cells

(2017) Anca-Laura Amati et al.   MEDIATORS OF INFLAMMATION

Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf

(2017) Kirsten Mary Hooper et al.   PLoS One

Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

(2017) Tomohiro Aoki et al.   Science Signaling

Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

(2017) Tomohiro Aoki et al.   Science Signaling

Lipids and immunoinflammatory pathways of beta cell destruction

(2016) Yumi Imai et al.   DIABETOLOGIA

Prostaglandin-E 1 has a protective effect on renal ischemia/reperfusion-induced oxidative stress and inflammation mediated gastric damage in rats

(2016) Selda Gezginci-Oktayoglu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2)

(2016) Jason W. Ashley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EETs/sEH in diabetes and obesity-induced cardiovascular diseases

(2016) Hui Huang et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Epoxyeicosatrienoic acids and glucose homeostasis in mice and men

(2016) James M. Luther et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Lipid Mediators Are Critical in Resolving Inflammation: A Review of the Emerging Roles of Eicosanoids in Diabetes Mellitus

(2015) Fernando H. G. Tessaro et al.   Biomed Research International

Group VIA Phospholipase A 2 Mediates Enhanced Macrophage Migration in Diabetes Mellitus by Increasing Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4

(2014) Chunyan Tan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice

(2014) Robert N. Bone et al.   DIABETES

Evidence of Contribution of iPLA2β-Mediated Events During Islet β-Cell Apoptosis Due to Proinflammatory Cytokines Suggests a Role for iPLA2β in T1D Development

(2014) Xiaoyong Lei et al.   ENDOCRINOLOGY

The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

(2013) Lindsey E. Padgett et al.   Annals of the New York Academy of Sciences

Role of Soluble Epoxide Hydrolase in Exacerbation of Stroke by Streptozotocin-Induced Type 1 Diabetes Mellitus

(2013) Sari A Jouihan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s Act on Distinct Phospholipid Pools in Zymosan-Stimulated Mouse Peritoneal Macrophages

(2013) L. Gil-de-Gomez et al.   JOURNAL OF IMMUNOLOGY

Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

(2013) Dhirendra K. Simanshu et al.   NATURE

Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer

(2013) Guodong Zhang et al.   PROGRESS IN LIPID RESEARCH

Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia

(2013) Yossi Issan et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Genetic modulation of islet β-cell iPLA2β expression provides evidence for its impact on β-cell apoptosis and autophagy

(2013) Xiaoyong Lei et al.   Islets

Endoplasmic Reticulum Stress, Pancreatic  -Cell Degeneration, and Diabetes

(2013) F. R. Papa   Cold Spring Harbor Perspectives in Medicine

Role of calcium-independent phospholipase A2β in human pancreatic islet β-cell apoptosis

(2012) Xiaoyong Lei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A2-VIA (iPLA2β)-knockout mice

(2012) Yewon Cheon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

(2012) R. Parsa et al.   DIABETES

Smooth Muscle-specific Expression of Calcium-independent Phospholipase A2β (iPLA2β) Participates in the Initiation and Early Progression of Vascular Inflammation and Neointima Formation

(2012) Shu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combination Therapy of an Inhibitor of Group VIA Phospholipase A 2 with Paclitaxel Is Highly Effective in Blocking Ovarian Cancer Development

(2011) Hui Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Platelet-activating factor and metastasis: calcium-independent phospholipase A2β deficiency protects against breast cancer metastasis to the lung

(2011) Jane McHowat et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Eicosanoids, β-cell function, and diabetes

(2011) Pengcheng Luo et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Reduced conduction reserve in the diabetic rat heart: role of iPLA2 activation in the response to ischemia

(2010) Parisa Rahnema et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

iPLA2, a novel determinant in Ca2+- and phosphorylation-dependent S100A8/A9 regulated NOX2 activity

(2010) Véronique Schenten et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

A link between endoplasmic reticulum stress-induced β-cell apoptosis and the group VIA Ca2+-independent phospholipase A2 (iPLA2β)

(2010) X. Lei et al.   DIABETES OBESITY & METABOLISM

Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes

(2010) R. Boizel et al.   DIABETOLOGIA

Diabetes-Induced Oxidative Stress Is Mediated by Ca2+-Independent Phospholipase A2 in Neutrophils

(2010) S. Ayilavarapu et al.   JOURNAL OF IMMUNOLOGY

Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA2β (VIA)-deficient mice

(2010) Mireille Basselin et al.   JOURNAL OF LIPID RESEARCH

Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis

(2009) Athena Kalyvas et al.   BRAIN

Lipidomic Analysis of Dynamic Eicosanoid Responses during the Induction and Resolution of Lyme Arthritis

(2009) Victoria A. Blaho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spontaneous Development of Endoplasmic Reticulum Stress That Can Lead to Diabetes Mellitus Is Associated with Higher Calcium-independent Phospholipase A2Expression

(2009) Xiaoyong Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-Independent Phospholipase A2 -Akt Signaling Is Involved in Lipopolysaccharide-Induced NADPH Oxidase 1 Expression and Foam Cell Formation

(2009) S.-H. Lee et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

(2009) Swarup K. Chakrabarti et al.   Obesity

Regulation of PSA secretion and survival signaling by calcium-independent phopholipase A2β in prostate cancer cells

(2009) Thomas M. Nicotera et al.   PROSTATE

Expression of Ca2+-independent and Ca2+-dependent phospholipases A2 and cyclooxygenases in human melanocytes and malignant melanoma cell lines

(2008) Mariagrazia Rita Scuderi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation

(2008) Jin-Gu Lee et al.   CELLULAR SIGNALLING

Calcium-independent Phospholipase A2(iPLA2β)-mediated Ceramide Generation Plays a Key Role in the Cross-talk between the Endoplasmic Reticulum (ER) and Mitochondria during ER Stress-induced Insulin-secreting Cell Apoptosis

(2008) Xiaoyong Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

iPLA2β: front and center in human monocyte chemotaxis to MCP-1

(2008) Ravi S. Mishra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2β in pancreatic β-cells and in iPLA2β-null mice

(2007) Shunzhong Bao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM