A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions

Humanized Mice as Unique Tools for Human-Specific Studies

(2018) Kylie Su Mei Yong et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

In silico design of novel probes for the atypical opioid receptor MRGPRX2

(2017) Katherine Lansu et al.   Nature Chemical Biology

A Novel Human Systemic Lupus Erythematosus Model in Humanised Mice

(2017) Merry Gunawan et al.   Scientific Reports

Epidemiology, Mechanisms, and Diagnosis of Drug-Induced Anaphylaxis

(2017) Maria Isabel Montañez et al.   Frontiers in Immunology

Humanized mouse model of mast cell–mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis

(2016) Paul J. Bryce et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Roles of Mas-related G protein–coupled receptor X2 on mast cell–mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases

(2016) Hariharan Subramanian et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hospitalization in older patients due to adverse drug reactions – the need for a prediction tool

(2016) Nibu Parameswaran Nair et al.   Clinical Interventions in Aging

Use of Humanized Mice to Study the Pathogenesis of Autoimmune and Inflammatory Diseases

(2015) Iurii Koboziev et al.   INFLAMMATORY BOWEL DISEASES

Potential effector and immunoregulatory functions of mast cells in mucosal immunity

(2015) L L Reber et al.   Mucosal Immunology

Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria

(2014) Daisuke Fujisawa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

(2014) Benjamin D. McNeil et al.   NATURE

Establishment of a Human Allergy Model Using Human IL-3/GM-CSF-Transgenic NOG Mice

(2013) R. Ito et al.   JOURNAL OF IMMUNOLOGY

Developmental Origin and Functional Specialization of Mast Cell Subsets

(2012) Michael F. Gurish et al.   IMMUNITY

Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice

(2012) Beatrix Schäfer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Studies of a ubiquitous receptor family

(2012) Bryan L. Roth et al.   NATURE

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis

(2011) Brady K Atwood et al.   BMC GENOMICS

Drug Allergy: An Updated Practice Parameter

(2010)   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Skin manifestations of drug allergy

(2010) Michael R. Ardern-Jones et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

(2009) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Are animal models predictive for humans?

(2009) Niall Shanks et al.   Philosophy Ethics and Humanities in Medicine

Immune-Mediated Adverse Drug Reactions

(2008) Jack Uetrecht   CHEMICAL RESEARCH IN TOXICOLOGY