Human Immunodeficiency Virus (HIV)–Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

(2019) Marion Pardons et al.   PLoS Pathogens

Blood CXCR3+ CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals

(2018) Riddhima Banga et al.   Frontiers in Immunology

Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency

(2018) Sushama Telwatte et al.   PLoS Pathogens

CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

(2017) Colleen S. McGary et al.   IMMUNITY

Proliferation of latently infected CD4+T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

(2017) Nina N. Hosmane et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus–Infected Individuals Receiving Suppressive Antiretroviral Therapy

(2017) Gabriela Khoury et al.   JOURNAL OF INFECTIOUS DISEASES

Defining total-body AIDS-virus burden with implications for curative strategies

(2017) Jacob D Estes et al.   NATURE MEDICINE

Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy

(2016) Gabriela Khoury et al.   AIDS

Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques

(2016) Daniel J. Stieh et al.   Cell Host & Microbe

Impairment of CCR6+and CXCR3+Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization

(2016) Valentina Cecchinato et al.   JOURNAL OF IMMUNOLOGY

CCR6− regulatory T cells blunt the restoration of gut Th17 cells along the CCR6–CCL20 axis in treated HIV-1-infected individuals

(2016) C Loiseau et al.   Mucosal Immunology

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals

(2016) Riddhima Banga et al.   NATURE MEDICINE

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

(2016) Rémi Fromentin et al.   PLoS Pathogens

CXCR3 ligands in disease and therapy

(2015) Katrien Van Raemdonck et al.   CYTOKINE & GROWTH FACTOR REVIEWS

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

(2015) Yoshinori Fukazawa et al.   NATURE MEDICINE

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

(2015) Julian H Elliott et al.   Lancet HIV

Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

(2014) A Kök et al.   Mucosal Immunology

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

(2014) Courtney V. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells

(2013) Steven A. Yukl et al.   AIDS

Quasispecies tropism and compartmentalization in gut and peripheral blood during early and chronic phases of HIV-1 infection: possible correlation with immune activation markers

(2013) G. Rozera et al.   CLINICAL MICROBIOLOGY AND INFECTION

A myriad of functions and complex regulation of the CCR7/CCL19/CCL21 chemokine axis in the adaptive immune system

(2013) Iain Comerford et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands

(2013) Y. Alvarez et al.   JOURNAL OF VIROLOGY

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

(2012) T. Duhen et al.   BLOOD

A Plasma Biomarker Signature of Immune Activation in HIV Patients on Antiretroviral Therapy

(2012) Anupa Kamat et al.   PLoS One

CCR6 as a mediator of immunity in the lung and gut

(2011) Toshihiro Ito et al.   EXPERIMENTAL CELL RESEARCH

Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin  7

(2011) P. Monteiro et al.   JOURNAL OF IMMUNOLOGY

Lack of Compartmentalization of HIV-1 Quasispecies Between the Gut and Peripheral Blood Compartments

(2011) Hiromi Imamichi et al.   JOURNAL OF INFECTIOUS DISEASES

HIV reservoirs and latency models

(2011) Matthew J. Pace et al.   VIROLOGY

Short Communication: Persistence of High Blood Levels of the Chemokines CCL2, CCL19, and CCL20 During the Course of HIV Infection

(2010) Julie Fontaine et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

(2010) Aimee El Hed et al.   JOURNAL OF INFECTIOUS DISEASES

Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy

(2010) Steven A. Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

Phylogeny and resistance profiles of HIV-1 POL sequences from rectal biopsies and blood

(2010) T.L. Katzenstein et al.   JOURNAL OF MEDICAL VIROLOGY

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton

(2010) P. U. Cameron et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy

(2008) Tae‐Wook Chun et al.   JOURNAL OF INFECTIOUS DISEASES

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

(2008) V Cecchinato et al.   Mucosal Immunology