Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency

Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistence

(2018) Javier Martinez-Picado et al.   Retrovirology

Assays for precise quantification of total (including short) and elongated HIV-1 transcripts

(2017) Philipp Kaiser et al.   JOURNAL OF VIROLOGICAL METHODS

Sensitive quantification of the HIV-1 reservoir in gut-associated lymphoid tissue

(2017) Sara Morón-López et al.   PLoS One

Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication

(2016) Stephanie L. Kohler et al.   JOURNAL OF IMMUNOLOGY

Defective proviruses rapidly accumulate during acute HIV-1 infection

(2016) Katherine M Bruner et al.   NATURE MEDICINE

Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries

(2016) Daniela Toro-Ascuy et al.   Viruses-Basel

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

(2016) Rémi Fromentin et al.   PLoS Pathogens

CDK11 in TREX/THOC Regulates HIV mRNA 3′ End Processing

(2015) Vladimir Pak et al.   Cell Host & Microbe

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency

(2015) Guillaume Mousseau et al.   mBio

HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells

(2015) Leonard Chavez et al.   PLoS Pathogens

Site-Specific Differences in T Cell Frequencies and Phenotypes in the Blood and Gut of HIV-Uninfected and ART-Treated HIV+ Adults

(2015) Steven A. Yukl et al.   PLoS One

TFH cells accumulate in mucosal tissues of humanized-DRAG mice and are highly permissive to HIV-1

(2015) Atef Allam et al.   Scientific Reports

Microbial exposure alters HIV-1-induced mucosal CD4+ T cell death pathways Ex vivo

(2014) Amanda K Steele et al.   Retrovirology

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

(2014) Julian H. Elliott et al.   PLoS Pathogens

Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model

(2014) Pejman Mohammadi et al.   PLoS Pathogens

A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells

(2013) Steven A. Yukl et al.   AIDS

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

(2013) Ya-Chi Ho et al.   CELL

The Distribution of HIV DNA and RNA in Cell Subsets Differs in Gut and Blood of HIV-Positive Patients on ART: Implications for Viral Persistence

(2013) Steven A. Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

Simian Immunodeficiency Virus Infects Follicular Helper CD4 T Cells in Lymphoid Tissues during Pathogenic Infection of Pigtail Macaques

(2013) Y. Xu et al.   JOURNAL OF VIROLOGY

Remodeling of the Enhancer Landscape during Macrophage Activation Is Coupled to Enhancer Transcription

(2013) Minna U. Kaikkonen et al.   MOLECULAR CELL

Highly Precise Measurement of HIV DNA by Droplet Digital PCR

(2013) Matthew C. Strain et al.   PLoS One

Transcriptional and Posttranscriptional Regulation of HIV-1 Gene Expression

(2013) J. Karn et al.   Cold Spring Harbor Perspectives in Medicine

An Analog of the Natural Steroidal Alkaloid Cortistatin A Potently Suppresses Tat-Dependent HIV Transcription

(2012) Guillaume Mousseau et al.   Cell Host & Microbe

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

(2012) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantification of Unintegrated HIV-1 DNA at the Single Cell Level In Vivo

(2012) Rodolphe Suspène et al.   PLoS One

Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency

(2012) Matthew J. Pace et al.   PLoS Pathogens

Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART

(2011) Véronique Avettand-Fenoel et al.   JOURNAL OF MEDICAL VIROLOGY

Triptolide (TPL) Inhibits Global Transcription by Inducing Proteasome-Dependent Degradation of RNA Polymerase II (Pol II)

(2011) Ying Wang et al.   PLoS One

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

(2010) Gilad Doitsh et al.   CELL

Differences in HIV Burden and Immune Activation within the Gut of HIV‐Positive Patients Receiving Suppressive Antiretroviral Therapy

(2010) Steven A. Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 mRNA 3′ End Processing Is Distinctively Regulated by eIF3f, CDK11, and Splice Factor 9G8

(2009) Susana T. Valente et al.   MOLECULAR CELL

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Transcriptional Interference Antagonizes Proviral Gene Expression to Promote HIV Latency

(2008) Tina Lenasi et al.   Cell Host & Microbe

Blood and Guts and HIV: Preferential HIV Persistence in GI Mucosa

(2008) Steven Yukl et al.   JOURNAL OF INFECTIOUS DISEASES

Persistence of HIV in Gut‐Associated Lymphoid Tissue despite Long‐Term Antiretroviral Therapy

(2008) Tae‐Wook Chun et al.   JOURNAL OF INFECTIOUS DISEASES