CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CD13/Aminopeptidase N Is a Potential Therapeutic Target for Inflammatory Disorders
Authors
Keywords
-
Journal
JOURNAL OF IMMUNOLOGY
Volume 204, Issue 1, Pages 3-11
Publisher
The American Association of Immunologists
Online
2019-12-18
DOI
10.4049/jimmunol.1900868
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration
- (2019) Mallika Ghosh et al. Science Signaling
- Angiogenic and Arthritogenic Properties of the Soluble Form of CD13
- (2019) Yuxuan Du et al. JOURNAL OF IMMUNOLOGY
- Multiple Sclerosis
- (2018) Daniel S. Reich et al. NEW ENGLAND JOURNAL OF MEDICINE
- Distinct Epitopes on CD13 Mediate Opposite Consequences for Cell Adhesion
- (2018) Claudia A. Garay-Canales et al. Biomed Research International
- APN/CD13 is over-expressed by Psoriatic fibroblasts and is modulated by CGRP and IL-4 but not by retinoic acid treatment
- (2017) Pascale Gerbaud et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Systemic Administration of Sialorphin Attenuates Experimental Colitis in Mice via Interaction With Mu and Kappa Opioid Receptors
- (2017) M Sałaga et al. Journal of Crohns & Colitis
- Clinical Significance of Tissue Factor and CD13 Double-Positive Microparticles in Sirs Patients with Trauma and Severe Sepsis
- (2017) Hisatake Matsumoto et al. SHOCK
- Anticancer Activity of Curcumin and Its Analogues: Preclinical and Clinical Studies
- (2016) Alessandro Allegra et al. CANCER INVESTIGATION
- CD13/aminopeptidase N is a negative regulator of mast cell activation
- (2016) Julia S. Zotz et al. FASEB JOURNAL
- Anti-inflammatory effect of novel analogs of natural enkephalinase inhibitors in a mouse model of experimental colitis
- (2016) Elżbieta Kamysz et al. Future Medicinal Chemistry
- The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion
- (2016) Christine A. Fiddler et al. PLoS One
- The pro-inflammatory cytokine 14-3-3 is a ligand of CD13 in cartilage
- (2015) M. Nefla et al. JOURNAL OF CELL SCIENCE
- CD13 Restricts TLR4 Endocytic Signal Transduction in Inflammation
- (2015) Mallika Ghosh et al. JOURNAL OF IMMUNOLOGY
- Psoriasis
- (2015) Wolf-Henning Boehncke et al. LANCET
- Osteoarthritis
- (2015) S Glyn-Jones et al. LANCET
- Bone Marrow Cells in Acute Lymphoblastic Leukemia Create a Proinflammatory Microenvironment Influencing Normal Hematopoietic Differentiation Fates
- (2015) Armando Vilchis-Ordoñez et al. Biomed Research International
- Molecular mechanisms regulating CD13-mediated adhesion
- (2014) Mallika Ghosh et al. IMMUNOLOGY
- Expression and Function of Aminopeptidase N/CD13 Produced by Fibroblast-like Synoviocytes in Rheumatoid Arthritis: Role of CD13 in Chemotaxis of Cytokine-Activated T Cells Independent of Enzymatic Activity
- (2014) Rachel Morgan et al. Arthritis & Rheumatology
- CD13 is essential for inflammatory trafficking and infarct healing following permanent coronary artery occlusion in mice
- (2013) Flavia E. Pereira et al. CARDIOVASCULAR RESEARCH
- A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets
- (2013) Sophia Adamia et al. CLINICAL CANCER RESEARCH
- Tyrosine Phosphorylation of CD13 Regulates Inflammatory Cell-Cell Adhesion and Monocyte Trafficking
- (2013) J. Subramani et al. JOURNAL OF IMMUNOLOGY
- The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing
- (2012) Alan H. M. Wong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake
- (2012) M. Ghosh et al. JOURNAL OF IMMUNOLOGY
- Evaluation of Th17-related cytokines and receptors in multiple sclerosis patients under interferon beta-1 therapy
- (2012) Gunes Esendagli et al. JOURNAL OF NEUROIMMUNOLOGY
- Structural basis for multifunctional roles of mammalian aminopeptidase N
- (2012) L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Psoriasis
- (2011) Gayathri K. Perera et al. Annual Review of Pathology-Mechanisms of Disease
- PETIR-001, a dual inhibitor of dipeptidyl peptidase IV (DP IV) and aminopeptidase N (APN), ameliorates experimental autoimmune encephalomyelitis in SJL/J mice
- (2011) Dirk Reinhold et al. BIOLOGICAL CHEMISTRY
- CD13+CD4+CD25hiregulatory T cells exhibit higher suppressive function and increase with tumor stage in non-small cell lung cancer patients
- (2011) Songwen Ju et al. CELL CYCLE
- IQGAP1 and its binding proteins control diverse biological functions
- (2011) Colin D. White et al. CELLULAR SIGNALLING
- Aminopeptidase N (EC 3.4.11.2) inhibitors (2006 – 2010): a patent review
- (2011) Li Su et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Divergent actions by inhibitors of DP IV and APN family enzymes on CD4+ Teff cell motility and functions
- (2011) Aliza Biton et al. IMMUNOBIOLOGY
- Systemic Lupus Erythematosus
- (2011) George C. Tsokos NEW ENGLAND JOURNAL OF MEDICINE
- Aminopeptidase N (CD13) as a target for cancer chemotherapy
- (2010) Malin Wickström et al. CANCER SCIENCE
- LYP, a novel bestatin derivative, inhibits cell growth and suppresses APN/CD13 activity in human ovarian carcinoma cells more potently than bestatin
- (2010) Jian-Jun Gao et al. INVESTIGATIONAL NEW DRUGS
- 14-3-3 associates with cell surface aminopeptidase N in the regulation of matrix metalloproteinase-1
- (2010) A. Ghaffari et al. JOURNAL OF CELL SCIENCE
- Neutrophil Apoptosis: Relevance to the Innate Immune Response and Inflammatory Disease
- (2010) Sarah Fox et al. Journal of Innate Immunity
- CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse
- (2010) B. Winnicka et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Inhibitory effect of anti-aminopeptidase N/CD13 antibodies on fibroblast migration
- (2010) Amy Lai et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Rheumatoid arthritis progression mediated by activated synovial fibroblasts
- (2010) Elena Neumann et al. TRENDS IN MOLECULAR MEDICINE
- CXCR3, Inflammation, and Autoimmune Diseases
- (2009) Stéphanie Lacotte et al. Annals of the New York Academy of Sciences
- Inflammatory Bowel Disease
- (2009) Clara Abraham et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD13 is a novel mediator of monocytic/endothelial cell adhesion
- (2008) Paola Mina-Osorio et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Diagnostic Value of the Aminopeptidase N, N-Acetyl-β-D-Glucosaminidase and Dipeptidylpeptidase IV in Evaluating Tubular Dysfunction in Patients with Glomerulopathies
- (2008) Branka Mitic et al. RENAL FAILURE
- The moonlighting enzyme CD13: old and new functions to target
- (2008) Paola Mina-Osorio TRENDS IN MOLECULAR MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now